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Doctor insights on: Safe Sulfasalazine Pregnant

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Is it safe to take sulfasalazine while pregnant or breastfeeding?

Is it safe to take sulfasalazine while pregnant or breastfeeding?

Probably, but ask OB: Adverse events have not been observed in animal reproduction studies.Sulfasalazine and sulfapyridine cross the placenta; a potential for kernicterus in the newborn exists.Based on available data, an increase in malformations in the developing fetus has not been observed following maternal use of sulfasalazine. As always, discuss this with both OB and your rheumatogist.Do not stop meds on your own. ...Read more

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Dr. Heidi Fowler
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Does the intake of folic acid needs to be increased while taking sulfasalazine during a pregnancy?

Does the intake of folic acid needs to be increased while taking sulfasalazine during a pregnancy?

YES!!!: Sulfasalazine increases need for folic acid. Because Folic Acid is most important in the first weeks of pregnancy those on sulfasalazine should take at least 1000 mcg/day prior to getting pregnant. About 1/3 of people have difficulty converting Folic Acid to the active form, l-5-mthf, so to be safe it is be best to take the l-5-mthf form. See http://www.Naturalnews.Com/drugwatch_sulfasalazine.Html. ...Read more

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Does anyone have problems with this drug, sulfasalazine?

Yes, sometimes: Up until the 80's we only had sulasalazine for uc. The main problems were headace and some rqshes usually due to the sulfapyridine moiety. Pure Mesalamine drugs such as asacol, lialda, Balsalazide and others do not contain the sulapyridine part and therefore don't have as many problems with the drug. However sulfasalazine is still cheap and useful and should not be ignored. ...Read more

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How long does sulfasalazine stay in your system?

How long does sulfasalazine stay in your system?

It depends: Sulfasalazine has a half life of 7.6 hr on avg. It's a short acting medication which is why it requires every 6-12 hour dosing. A drug is cleared from system entirely after 10 half lives so the drug should theoretically be cleared in 76 hrs or a little over 3 days. The metabolite of sulfasalazine, sulfapyridine has a half life of 10.4-14.8 h so it's cleared in 148 hrs from system ...Read more

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Will sulfasalazine make me lose any weight?

Will sulfasalazine make me lose any weight?

No.: Only if you had been on steroids and are now off of them. But sfz does not cause weight loss, unless the occasional GI quiziness that some patients get is making you eat less. ...Read more

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Is sulfasalazine an unhealthy drug?

Is sulfasalazine an unhealthy drug?

No.relatively safe!: Sfz is one drug I use the most in patients with many diseases. Aside from an occasional "sulfa rxn", the most common side effect is stomach "queazyness". All individuals taking this drug need to be monitored with blood work at defined intervals (2-3 mo) and they should receive Folic Acid supplements. ...Read more

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Has anyone prescribed sulfasalazine for costochondritis?

Has anyone prescribed sulfasalazine for costochondritis?

No: The use of sulfasalazine would be very unusual for this inflammatory condition. Local heat, anti-inflammatory rx, steroid injection ( with caution), some types of physical therapy are the usual treatments. ...Read more

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