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Doctor insights on: Safe Onglyza Pregnant

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Is it safe to take onglyza (saxagliptin) while pregnant?

Is it safe to take onglyza (saxagliptin) while pregnant?

Category B: It is considered a category b, which means no risk or adverse fetal effects have been shown but no controlled human first trimester studies are available to confirm. There does not appear to be a risk in the second or third trimester. ...Read more

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Dr. Jeffrey Satinover
4 doctors shared insights

Pregnancy (Definition)

When your due date arrives, you will be more than ready to have your baby! Most women deliver the baby somewhere between 37 and 42 weeks. According to the American College of Obstetricians and Gynecologists, only 5% of babies arrive on the exact due date. Approximately 7% of babies are not delivered by 42 weeks, and when that happens, it is referred to ...Read more


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I'm taking onglyza (saxagliptin) 2.5mg and metformin 500mg for a month now. Is this safe? I want to be off these medicines. Will I be cured if taking them?

I'm taking onglyza (saxagliptin) 2.5mg and metformin 500mg for a month now.  Is this safe?  I want to be off  these medicines.  Will I be cured if taking them?

No cures: Metformin, available for almost 50 years is very safe in people with good kidney function. The dpp4s - of which Onglyza (saxagliptin) is one - have been implicated in pancreatitis, and pancreas and thyroid cancers. Talk to your doctor if you are worried. ...Read more

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Is it safe to take onglyza (saxagliptin) and metformin at the same time?

Is it safe to take onglyza (saxagliptin) and metformin at the same time?

Yes: They are a good combination. There is also a pill that combined both of them together called kombiglyze that is fda-approved for the treatment of type 2 diabetes. ...Read more

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Is onglyza (saxagliptin) safe for long-term treatment? Has anyone gotten cancer or severe complications from it?

Is onglyza (saxagliptin) safe for long-term treatment?  Has anyone gotten cancer or severe complications from it?

Generally safe.: Onglyza (saxagliptin) is not associated with cancer. There are reports of pancreatitis with Onglyza (saxagliptin) and the other dpp-4 inhibitors but that is considered infrequent. Generally Onglyza (saxagliptin) is well tolerated and not associated with significant long term side effects. ...Read more

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I found onglyza (saxagliptin) may be bad for the pancreas (negative cell multiplication leading to pancreatitis or cancer). Is this drug safe to take?

I found onglyza (saxagliptin) may be bad for the pancreas (negative cell multiplication leading to pancreatitis or cancer). Is this drug safe to take?

yes if appropriate: There was a huge trial on this drug just got published and no increased risk of pancreatitis or cancer was found. The rate of pancreatitis was 0.3% for both placebo and Onglyza (saxagliptin) group. ...Read more

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Can luvox be used with vytoryn and onglyza (saxagliptin)?

Can luvox be used with vytoryn and onglyza (saxagliptin)?

Possibly: Luvox (fluxoxamine, an SSRI) is predominantly metabolized in the liver. it can inhibit (slow down) cytochromes in the liver, which r used 2 metabolize other drugs. This would have the effect of increasing the circulating levels of certain other meds. taking Luvox can increase the blood level of vytorin (ezetimibe and simvastatin) or onglaza. Discuss potential interactions with ur doc & determine the best treatment 4 u :) ...Read more