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Doctor insights on: Rosiglitazone And Glimepiride Medication

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What happens if a nondiabetic person takes 3 avandaryl (rosiglitazone and glimepiride)?

What happens if a nondiabetic person takes 3 avandaryl (rosiglitazone and glimepiride)?

Low blood sugar: The Amaryl (glimepiride) in this medication stimulates the pancreas to release Insulin and would likely cause an abnormally low blood sugar if taken by a non diabetic person. ...Read more

Dr. Lee Peter Bee
19 Doctors shared insights

Rosiglitazone (Definition)

Rosiglitazone is a thiazolidinedione, a class of diabetic medication that acts as a Insulin sensitizer by binding to the ppar receptors of the fat cells. The trade name is avandia (rosiglitazone). As a class effect of the medication, it can cause fluid retention and leads to worsening ...Read more


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What is the definition or description of: avandaryl (rosiglitazone and glimepiride)?

What is the definition or description of: avandaryl (rosiglitazone and glimepiride)?

Combination drug: Of Avandia (rosiglitazone) and a sulfonylurea
2 drugs for diabetes

avandia now severly restricted by fda- should be removed from market- had increased adverse cardiovascular outcomes

sulfonylureas, as a separate pill, are still on market, but have high risk of low blood sugar and weight gain, so we avopid using them

much better meds available. ...Read more

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What will happen if a non-diabetic takes 3 avandaryl (rosiglitazone and glimepiride)?

What will happen if a non-diabetic takes 3 avandaryl (rosiglitazone and glimepiride)?

Your blood: Sugar will go down. It's unlikely there will be any significant consequences, as your body will respond with an increase in blood sugar -- but it should be avoided. ...Read more

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What to do if I have no idea what avandaryl (rosiglitazone and glimepiride) does, but I need something to make me go to sleep so I popped three, what does it do?

What to do if I have no idea what avandaryl (rosiglitazone and glimepiride) does, but I need something to make me go to sleep so I popped three, what does it do?

Who gave it to you?: "Popping" three pills whose effect you do not know is generally a bad idea. Avandaryl (rosiglitazone and glimepiride) is a medicine for DIABETES. It has nothing to do with sleep. It causes a drop in your blood sugar. If this happens when you are asleep, you could be in real trouble (i.e., permanent brain damage). In this case, what you would get is not sleep, but a coma. ...Read more

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Is it safe to take avandaryl (rosiglitazone and glimepiride) while pregnant or breastfeeding?

Is it safe to take avandaryl (rosiglitazone and glimepiride) while pregnant or breastfeeding?

No: Avandia, a component in Avandaryl (rosiglitazone and glimepiride) generally isn't recommended during pregnancy or nursing. Talk to your doctor about alternative medications like metformin or insulin. ...Read more

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I am a type 2 diabetic and am taking avandia (rosiglitazone) and amaryl can they make you gain weight as a side effect?

I am a type 2 diabetic and am taking avandia (rosiglitazone) and amaryl can they make you gain weight as a side effect?

Avandia (rosiglitazone) and Amaryl: Avandia (rosiglitazone) can cause fluid retention, however, Insulin levels in type 2 diabetics is usally high. The sulfonoureas like ameryl, increase the level of insulin. This causes weight gain. All drugs of this class carry an fda black box warning on increased mortality and morbidity. Metformin is the first drug that should be tried. Period. ...Read more

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Please describe the medication: amaryl (glimepiride)?

Glimepiride for DIAB: Amaryl (glimepiride) is brand name for glemipiride, a long acting sulphonylurea used to treat diabetes mellitus. ...Read more

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Please describe the medication: avandia (rosiglitazone)?

Please describe the medication: avandia (rosiglitazone)?

Avandia (rosiglitazone): Is an anti-diabetic drug that works as an Insulin sensitizer. Some side-effects are heart disease & liver toxicity. ...Read more

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Side effects of diabetic medication glimepiride?

Side effects of diabetic medication glimepiride?

Extremely low blood: Sugar levels, just like any other medicine that forces your pancreas to make more insulin. ...Read more

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Please describe the medication: glimepiride?

Please describe the medication: glimepiride?

Diabetes medication: Treats type 2 diabetes. Used together with a proper diet and exercise to help control high blood sugar. This medicine is a sulfonylurea. ...Read more

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Please describe the medication: rosiglitazone?

Please describe the medication: rosiglitazone?

Thiazolindinedione: Rosiglitazone is a thiazolidinedione, a class of diabetic medication that acts as a Insulin sensitizer by binding to the ppar receptors of the fat cells. The trade name is avandia (rosiglitazone). As a class effect of the medication, it can cause fluid retention and leads to worsening of congestive heart failure. ...Read more

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What difference is there between glyburide and glimepiride medications?

What difference is there between glyburide and glimepiride medications?

Same family: Hi. Glyburide is a second generation sulfonylurea and glimepiride is a 3rd generation. They work at the same receptors on the beta cell (the pancreatic cells that make insulin) and stimulate insulin release. Glimepiride is preferable because of less metabolite build up in kidney disease, but they're VERY similar. I never use them. In my opinion, based on good science, we have much better drugs. ...Read more

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What difference is there between glyburide and glimepiride medications?

Diabetes: Either glyburide or glimepiride can be prescribed for management of diabetes. There may be a cost difference in your favor or you doctor may have a good reason to prescribe one or the other.
More important - you need to take control of your eating habits, your weight (if overweight), and your exercise.
Also please remember to measure your blood sugar regularly. Your doctor will advise you on dose ...Read more

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Please explain what are the differences between glyburide and glimepiride medications?

Please explain what are the differences between glyburide and glimepiride medications?

Similar mechanisms: Hi. Glyburide & glimepiride (& glipizide & others in the sulfonylurea class, for that matter) all work by the same mechanism to stimulate endogenous insulin release. They differ in duration of action, metabolites, accumulation in kidney disease, etc. They're archaic drugs that I never use anymore. There are much better type 2 drugs out there. Their one benefit - they're cheap. ...Read more

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What are the contents or ingredients of avandia (rosiglitazone) diabetes drug?

Rosilitazone: I have to have a special license to continue to give it from a central pharmacy. I have only 1 patient still taking it. ...Read more

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Avandia (rosiglitazone) is a miracle drug for my diabetes, is it safe to take?

Avandia (rosiglitazone) is a miracle drug for my diabetes, is it safe to take?

Causes heart problem: Avandia (rosiglitazone) is a type of oral medication used to lower blood sugar in type 2 diabetes, however in large studies patients taking Avandia (rosiglitazone) had an increased risk of heart attack and heart failure compared to other diabetes drugs, therefore it is only to be used by patients who can't take other anti diabetes medications. Excercise and keeping weight normal is extremely important to decrease need for drugs. ...Read more

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I use 4 mg amaryl (glimepiride) morn and night, added 100 mg invokana, sugar 150-165 at night, can I increase either drug, 61 yr male, 189 lbs, a runner.

Yes: Invokana can be increased up to 300mg/day in patients that tolerate the drug. It appears that you are already at the max daily dose of amaryl, (glimepiride) and likely wouldn't add an additional benefit to increase the dose. You should talk with your doctor before increasing any drug. ...Read more

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Are Glimepiride & glipizide the same drug?

No, but same class: Both are 2nd generation sulfonylurea drugs for treatment of Type 2 Diabetes. According to a review by the Utah gov't, they conclude: "Overall ranges of HbA1c reduction seen w/glimepiride, glipizide & glyburide treatment in current literature are similar & choice of antidiabetes therapy should be based on individual patient characteristics, including: efficacy, cost, (see below) ...Read more

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Avandia (rosiglitazone) is a miracle drug for my diabetes, but heard it is not safe to take?

Avandia (rosiglitazone) is a miracle drug for my diabetes, but heard it is not safe to take?

Not known for sure.: Some evidence from medical studies suggests that patients who take this medication have higher rates of heart disease and heart failure. This evidence is by no means complete, but it has led to the fda to limit strictly how this medication is prescribed. If your doctor is willing to prescribe the medication and you are doing well with it, it can be continued after careful consideration. ...Read more

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Are glimepiride&metformin safe drugs for a diabetic of12yrs. Cretanine now 1.2.Are these drugs safe or they shud be changed. Any advice to change meds.

Are glimepiride&metformin safe drugs for a diabetic of12yrs. Cretanine now 1.2.Are these drugs safe or they shud be changed. Any advice to change meds.

Yes.: Metformin is considered first line therapy for type II diabetics. It should be stopped if your creatinine goes over 1.3-1.4 or for certain procedures using contrast dye for a couple days. The advantage for both is that they are cheap. Are there better choices than glimipiride? Yes. It pushes the pancreas to secrete more insulin and can "wear out" cells. Newer options exist but expensive. ...Read more

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Glimepiride and metformin hydrochloride, which group of drug and what is it used for?

Both type 2 drugs: Hi. Metformin and glimepiride are both type 2 drugs. Metformin is an insulin sensitizer - makes tissues (predominantly liver but also muscle) more sensitive to insulin. Glimepiride is an insulin secretogogue - makes your own pancreas secrete more insulin. They are synergistic used in combination. To your good diabetes control! ...Read more

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Glimepiride and metformin hydrochloride, what group of drug and what purpose does it used?

Type 2 drugs: Hi. Metformin is an insulin sensitizer and predominantly works at the liver to increase sensitivity to your own insulin (or exogenous insulin) to reduce the release of sugar from your liver into the blood. Glimepiride stimulates the release of insulin from your pancreas (insulin secretogogue). The 2 drugs are synergistic together. They may or may not control your diabetes. Good control is the goal ...Read more

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Glimepiride and metformin hydrochloride which group of drug are they in and what are their purposes?

Treat Diabetes: Diabetes is a condition where Insulin does not work well and there is insufficient insulin. Metformin works to overcome some of the Insulin resistance and reduce excessive glucose production from the liver.
Glimepiride works on the cells that make Insulin to augment Insulin deficiency and both together lower blood sugar. ...Read more

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Is rosiglitazone a safe drug for diabetes if heart disease?

Is rosiglitazone a safe drug for diabetes if heart disease?

No: Whether you believe the data or not, I do not recommend using rosiglitazone in patients with heart disease. There are many other alternatives for this drug. The best one depends on the individual patient's characteristics and degree of control. ...Read more

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If you have had a heart attack and are a diabetic and have taken avandia (rosiglitazone) how do you know if its from the drug?

If you have had a heart attack and are a diabetic and have taken avandia (rosiglitazone) how do you know if its from the drug?

You don't: Avandia (rosiglitazone) has been linked to increased risk of cardiovascular events, but you cannot tell a heart attack due to Avandia (rosiglitazone) versus a heart attack due to something else, such as your diabetes. ...Read more

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Hyperglycemic patient, a sudden hyperglycemia to more than 430 ml/dl, what type of emergency drug can be used in home? Pt use glimepiride & metformin

Hyperglycemic patient, a sudden hyperglycemia to more than 430 ml/dl, what type of emergency drug can be used in home? Pt use glimepiride & metformin

Insulin: The only way to address rapid rise in blood glucose is with a sliding scale of regular Insulin (or its equivalent injectable). The pills take too long and are too broad-acting to use for this purpose. If happens more than once every several months, talk to dr about having an Insulin option to help 'reset' blood glucose when climbing too high. ...Read more

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Are there many recalls on avandia (rosiglitazone)?

Are there many recalls on avandia (rosiglitazone)?

Rosiglitazone has: Been linked to heart problems. The suits are beginning. I do not know if it remains on the market. ...Read more

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Are there any safe substitutions for avandia (rosiglitazone)?

Are there any safe substitutions for avandia (rosiglitazone)?

Pioglitazone: Or actos, (pioglitazone) but there are reports of bladder cancer with it. The class is decreasing in use. I quit not out of cancer fear, but co-pay. ...Read more

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What should you do if you missed a dose of glimepiride?

What should you do if you missed a dose of glimepiride?

Depends: Generally if you miss a dose, you take it as soon as you remember unless it’s almost time to take your next dose, then you would skip the missed dose. ...Read more

Dr. Mark Pack
72 Doctors shared insights

Glimepiride (Definition)

Treats type 2 diabetes. Used together with a proper diet and exercise to help control high blood sugar. This ...Read more


Dr. Ana Adelstein
58 Doctors shared insights

Amaryl (Definition)

Amaryl is a second generation sulfonylurea which is a kind of diabetes-related drug ...Read more