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Doctor insights on: Rnp Ena

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Rnp Antibody (Definition)

http://www.mayomedicallaboratories.com/test-catalog/clinical+and+interpretive/81357. ...Read more


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Ana test results 1:320 mean? Speckled homogeneous

Ana test results 1:320 mean? Speckled homogeneous

Not necessarily: The ANA is a screening test for lupus but is not specific. It can be positive in numerous other diseases and in normal people. It has to be evaluated in the context of the clinical picture and the results of other autoantibody tests. ...Read more

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Sm/rnp antibody- ANA choice- positive, speckled/titer: 1:1280; sm & rnp (done alone) negative; sm/rnp antibody (together?) positive 3.0 guessing mctd?

Sm/rnp antibody- ANA choice- positive, speckled/titer: 1:1280; sm & rnp (done alone) negative; sm/rnp antibody (together?) positive 3.0 guessing mctd?

Heads up: One of the things that's frustrating about these antibody tests looking for different connective tissue diseases is that they are difficult to do and are fraught with pitfalls. I suspect you've had at least one lab error to complicate your workup. Have you have a tube test for u1-rnp? Your clinical symptoms and signs actually tell more about your diagnosis ; best direction for treatment. ...Read more

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ANA 1:80 speckled, SM, RNP, SCL-70 detected.Leukocyte, urate, alkaline phosphate,creatinine low. Albumin, triglycerides high. Pos HAV, HBV. Rhem. Neg?

ANA 1:80 speckled, SM, RNP, SCL-70 detected.Leukocyte, urate, alkaline phosphate,creatinine low. Albumin, triglycerides high. Pos HAV, HBV. Rhem. Neg?

Not enough info: Lab tests need to be evaluated in the context of the clinical symptoms. You need this issue evaluated by a rheumatologist ...Read more

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How about Ana screen positive, Ana titer (ifa) 1:80 Hi, and pattern speckled?

How about it?: Up to a quarter of women your age have an ANA (immunofluorescent antibody) at a low titer like yours with a speckled pattern. If there's a question of whether you have lupus or one of its relatives, it's a piece of information to note and file for future reference. A negative ANA would rule several things out. Your result proves nothing positive. Best wishes. ...Read more

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Ana 12 profile it came back positive 1:40 speckled cardiolipin IgM 18.6?

See below: Both of these are low values and should not be used for a specific diagnosis. However, the most important feature is why were these labs drawn. For example what symptoms you were having to have the labs drawn and in that case they may mean slightly more, but just looking at the labs they are low values and dont point to one specific disease. ...Read more

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What does this mean ? SSB(La)IGG Positive 85 SSA(Ro)AB IGG Neg. ANA NEG. SED RATE Neg. CRP Neg. RF NEG.

Depends: All lab results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that antibodies to SSA suggest auto-immune disorder, however, if that is the only abnormal test and you do not have any symptoms, I would leave it alone and re-evaluate in six months. ...Read more

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(Biopsy DLE Inconclusive)ds-DNA Normal.Weak Positive ANA,ENA R Positive ANT RNP positive FBC &Urine Ok.Photosen,Rash face&Ears blister fingers... SLE?

(Biopsy DLE Inconclusive)ds-DNA Normal.Weak Positive ANA,ENA R Positive ANT RNP positive FBC &Urine Ok.Photosen,Rash face&Ears blister fingers... SLE?

No: DLE , even if you have it, does not necessarily translate into SLE in the absence of other system involvement. True blisters are not usually found with DLE. Have you been checked for porphyria? ...Read more

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Ana screen, ifa positive a (negative) means?

Ana screen, ifa positive a  (negative)   means?

Nothing by itself: One person in four tests positive. The vast majority of these people have no problems. The clinical picture is key, and how high the titer is may be helpful. ...Read more

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Ana screen positive, ANA titer 320, rash very often on face, nucleolar pattern. Any significance?

Yes: The pattern is not important but a facial rash and a positive ANA suggest the possibility of some form of lupus. ...Read more

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ENA test screened for SS-A, SS-B, RNP, Sm, Scl-70 & Jo-1. Negative result. I'm ok?

ENA test screened for SS-A, SS-B, RNP, Sm, Scl-70 & Jo-1. Negative result. I'm ok?

May be: Why were these tests done? You must have had some symptoms for your doctor to order these tests. Negative results on blood tests are not an assurance that there is no disease. Please follow your doctor's advice for follow-up care. ...Read more

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I'm having negative DNA ,Sm and Rnp antibodies, but positive sm/rnp antibody,and high ANA titre speckled,so what is the diagnosis ?

Lupus: These serologies are rather non specific. The speckled ANA is non specific. In Systemic Lupus Erythematosis (SLE) it is usually homogeneous in its staining. Anti-Sm and Anti RNP can be see in mixed connective-tissue diseases and overlaps with SLE, scleroderma and myositis. As often is the case a specific diagnosis cannot be made. You need to see a Rheumatologist. ...Read more

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ANA positive SSA SSB weekly positive SCL weekly positive RNP SM weekly positive. Any implications? What are the differential diagnosis? WaDoes it mean

ANA positive SSA SSB weekly positive SCL weekly positive RNP SM weekly positive. Any implications? What are the differential diagnosis? WaDoes it mean

Pos auto ab tests: You are describing positive tests for auto antibodies. The differential diagnosis can be extensive. I am assuming a rheumatologist has ordered these tests? You need f/u with them to educate you what they mean, what further tests may need to be done and review your symptoms. Proper rheum DX is not based only on test results, but exam findings and symptoms of patient. Good luck. ...Read more

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What would cause a high positive ANA (1:640) speckled, nucleolar with a low positive smooth muscle antibody (1:40) but negative SS-A, SS-B, anti-Smith, RNP, SCL-70, Anti Jo antibodies? Liver disease?

Probably normal: Many people have a positive ANA without being sick. If you also have elevated liver enzymes, a workup for autoimmune hepatitis may be continued, but if there's nothing to suggest a liver problem biochemically, I'd not be in a hurry to diagnose despite anti-smooth-muscle. ANA means nothing apart from the clinical picture. Best wishes. ...Read more