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Doctor insights on: Rnp Antibody Test

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Had lab test done. Sm/rnp antibody 2.5 pos. What does this mean?

Had lab test done.  Sm/rnp antibody   2.5 pos.   What does this mean?

Probably nothing: That low titer is not impressive, usually the RNP. Ask the doctor who ordered it. Why was the test ordered in the first place? ...Read more

Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


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Can there be false positive rnp antibody tests even with a high titre of an ana?

Can there be false positive rnp antibody tests even with a high titre of an ana?

FALSE POSITIVE RNP: It is possible we need to know what your symptoms and signs are, and why the tests have been ordered.The lab test apways have to be interpreted along with complete clinacal findings if you have signs and symptoms of lupus, high ana, and doctor ordered rnp to confirm the diagnosis and it comes out positive.That in all probabilities is positive and not false positive. ...Read more

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What is the definition or description of: rnp antibody?

What is the definition or description of: rnp antibody?

Anti-RNP: http://www.mayomedicallaboratories.com/test-catalog/clinical+and+interpretive/81357.

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I was just diagnosd with mctd...No symptoms just rnp antibody of 1.9 and anachoice screen-positive...What lies ahead for me?

I was just diagnosd with mctd...No symptoms just rnp antibody of 1.9  and anachoice screen-positive...What lies ahead for me?

Diagnosis?: Connective tissue diseases can only be diagnosed if a person has symptoms and physical signs of a disease. Mctd cannot be diagnosed by blood test alone as a percent of the normal population has a positive rnp without any disease. It is not like checking your blood type (a positive, o negative, etc.). Ask your doctor how the diagnosis of mctd was made. ...Read more

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I'm having negative DNA ,Sm and Rnp antibodies, but positive sm/rnp antibody,and high ANA titre speckled,so what is the diagnosis ?

Lupus: These serologies are rather non specific. The speckled ANA is non specific. In Systemic Lupus Erythematosis (SLE) it is usually homogeneous in its staining. Anti-Sm and Anti RNP can be see in mixed connective-tissue diseases and overlaps with SLE, scleroderma and myositis. As often is the case a specific diagnosis cannot be made. You need to see a Rheumatologist. ...Read more

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Sm/rnp antibody- ANA choice- positive, speckled/titer: 1:1280; sm & rnp (done alone) negative; sm/rnp antibody (together?) positive 3.0 guessing mctd?

Heads up: One of the things that's frustrating about these antibody tests looking for different connective tissue diseases is that they are difficult to do and are fraught with pitfalls. I suspect you've had at least one lab error to complicate your workup. Have you have a tube test for u1-rnp? Your clinical symptoms and signs actually tell more about your diagnosis ; best direction for treatment. ...Read more

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I was just diagnosd with mctd rnp antibody of 1.9 and anachoice screen-positive the only symptom is joint pain in my hand/wrist (i do have carpal tnl?

I was just diagnosd with mctd rnp antibody of 1.9 and anachoice screen-positive the only symptom is joint pain in my hand/wrist (i do have carpal tnl?

Positive Labs: Positive labs are meaningless unless you have symptoms. At this point, your doctor is aware of the positive results and will likely follow your symptoms. The positive simply means you are at a greater chance of developing symptoms though not everybody does. ...Read more

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After sore throat, blood panel revealed infection and possible mono. Only other off number was rnp antibody of 5.8. Ana of 5. Could mono cause uprnp?

After sore throat, blood panel revealed infection and possible mono. Only other off number was rnp antibody of 5.8. Ana of 5. Could mono cause  uprnp?

No.: Your serologies suggest mctd, or mixed connective tissue disease. This is much milder than systemic lupus erythematosis, and in 28 years, I have never had a dire situation with any patient with this DX alone. There is no relationship with mononucleosus. Most patients are treated with hydroxycholorquine or low dose prednisone. Aches and pains: aleve! don't worry about it! ...Read more

Dr. Creighton Wright
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Rnp Antibody (Definition)

http://www.mayomedicallaboratories.com/test-catalog/clinical+and+interpretive/81357. ...Read more