Rnp antibody levels - Doctor answers

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Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


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What is the definition or description of: rnp antibody?

What is the definition or description of: rnp antibody?

Anti-RNP: Http://www. Mayomedicallaboratories. Com/test-catalog/clinical+and+interpretive/81357.

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Given a positive RNP antibody test, what are the clinical diagnostic criteria for MCTD?

Given a positive RNP antibody test, what are the clinical diagnostic criteria for MCTD?

MCTD: Usually considered diagnostic if high RNP titer, and two or more of the following: Raynauds, myositis, synovitis and swollen fingers/hands. ...Read more

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Had lab test done. Sm/rnp antibody 2.5 pos. What does this mean?

Had lab test done. Sm/rnp antibody 2.5 pos. What does this mean?

Probably nothing: That low titer is not impressive, usually the RNP. Ask the doctor who ordered it. Why was the test ordered in the first place? ...Read more

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Can there be false positive rnp antibody tests even with a high titre of an ana?

Can there be false positive rnp antibody tests even with a high titre of an ana?

FALSE POSITIVE RNP: It is possible
we need to know what your symptoms and signs are, and why the tests have been ordered. The lab test apways have to be interpreted along with complete clinacal findings
if you have signs and symptoms of lupus, high ana, and doctor ordered rnp to confirm the diagnosis and it comes out positive. That in all probabilities is positive and not false positive. ...Read more

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I was just diagnosd with mctd...No symptoms just rnp antibody of 1.9 and anachoice screen-positive...What lies ahead for me?

I was just diagnosd with mctd...No symptoms just rnp antibody of 1.9 and anachoice screen-positive...What lies ahead for me?

Diagnosis?: Connective tissue diseases can only be diagnosed if a person has symptoms and physical signs of a disease. Mctd cannot be diagnosed by blood test alone as a percent of the normal population has a positive rnp without any disease. It is not like checking your blood type (a positive, o negative, etc.). Ask your doctor how the diagnosis of mctd was made. ...Read more

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I'm having negative DNA, Sm and Rnp antibodies, but positive sm/rnp antibody, and high ANA titre speckled, so what is the diagnosis?

I'm having negative DNA, Sm and Rnp antibodies, but positive sm/rnp antibody, and high ANA titre speckled, so what is the diagnosis?

Lupus: These serologies are rather non specific. The speckled ANA is non specific. In Systemic Lupus Erythematosis (SLE) it is usually homogeneous in its staining. Anti-Sm and Anti RNP can be see in mixed connective-tissue diseases and overlaps with SLE, scleroderma and myositis. As often is the case a specific diagnosis cannot be made. You need to see a Rheumatologist. ...Read more

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Sm/rnp antibody- ANA choice- positive, speckled/titer: 1:1280; sm & rnp (done alone) negative; sm/rnp antibody (together?) positive 3.0 guessing mctd?

Heads up: One of the things that's frustrating about these antibody tests looking for different connective tissue diseases is that they are difficult to do and are fraught with pitfalls. I suspect you've had at least one lab error to complicate your workup. Have you have a tube test for u1-rnp? Your clinical symptoms and signs actually tell more about your diagnosis ; best direction for treatment. ...Read more

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I was just diagnosd with mctd rnp antibody of 1.9 and anachoice screen-positive the only symptom is joint pain in my hand/wrist (i do have carpal tnl?

I was just diagnosd with mctd rnp antibody of 1.9 and anachoice screen-positive the only symptom is joint pain in my hand/wrist (i do have carpal tnl?

Positive Labs: Positive labs are meaningless unless you have symptoms. At this point, your doctor is aware of the positive results and will likely follow your symptoms. The positive simply means you are at a greater chance of developing symptoms though not everybody does. ...Read more

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Went to dr with hand, shoulder, hip joint pain. Ana reflex screen Ana positive 1.0 and rnp antibody positive 4.3. All others neg. Very scared!

Went to dr with hand, shoulder, hip joint pain. Ana reflex screen Ana positive 1.0 and rnp antibody positive 4.3. All others neg. Very scared!

Lab numbers: These numbers don't show changes at joints and with most auto immune disorders, you may have periods of pain and increased lab numbers, usually related to stress in your life, and once treated medically or with stress reduction, pain/lab should improve. May want xray of one of involved joints just inflamed which can return to baseline. ...Read more

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After sore throat, blood panel revealed infection and possible mono. Only other off number was rnp antibody of 5.8. Ana of 5. Could mono cause uprnp?

After sore throat, blood panel revealed infection and possible mono. Only other off number was rnp antibody of 5.8. Ana of 5. Could mono cause uprnp?

No.: Your serologies suggest mctd, or mixed connective tissue disease. This is much milder than systemic lupus erythematosis, and in 28 years, I have never had a dire situation with any patient with this DX alone. There is no relationship with mononucleosus. Most patients are treated with hydroxycholorquine or low dose prednisone. Aches and pains: aleve! Don't worry about it! ...Read more

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Got my test results online. Says ANA speckled is at 1250. And other antibodies are found like ssa, ssb, rnp, smith, but are low levels. This mean SLE?

Got my test results online. Says ANA speckled is at 1250. And other antibodies are found like ssa, ssb, rnp, smith, but are low levels. This mean SLE?

Not necesarily: While these tests point to a probability of a collagen vascular disease, this could be lupus, mixed connective tissue disease, etc. The doctor ordering these tests knows your history and physical examination findings and should be the one interpreting these tests. Should be a Rheumatologist. ...Read more

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Does it matter what the titre of rnp antibodies are when it is the only single one identified in diagnosing mixed connective tisseue disease?

Does it matter what the titre of rnp antibodies are when it is the only single one identified in diagnosing mixed connective tisseue disease?

No: The diagnosis of mctd must first be made if the history and physical examination are indicative of a possible connective tissue disease. If those elements are present and the disease seems to overlap between conditions such as lupus and polymyositis and others, it is reasonable to do laboratory testing. Only then, if the rnp is above the reference lab normal, it will confirm mctd. Rnp alone: no dx. ...Read more

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What does a weakly positive ANA with only rnp antibodies indicate?

Specific to patient: The test by itself is not diagnostic. It depends on your evaluation, examination, clinical factors are the most pertinent. The lab reports are guidelines but not diagnostic in themselves. ...Read more

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I had a ANA test done everything came back good beside rnp antibodies. Value 1.8 reference range 0.0-0.9. Everything else was good is this bad.

It is barely positiv: So results must be interpreted very carefully with all clinical symptoms taken into account. A test by itself is just a test. You might need a good rheumatologist ...Read more

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I have been reading online and have read that when the rnp is the only antibody that is positive that this indicated mixed connective tissue disease?

I have been reading online and have read that when the rnp is the only antibody that is positive that this indicated mixed connective tissue disease?

Labs can confuse.: The labs are just a fraction of what needed to get you better. Your history and physical exam will determine your treatment. Looking for which labs will delay and confuse. You need to develop a few paragraphs of all your issues and sit down with your doctor to put the pieces together.
Began a wellness program and add in magnesium and acupuncture. ...Read more

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What could a negative ANA and positive RNP antibodies mean? I have a history of chronic rheumatological symptoms, but my dr is not convinced its MCTD.

Lab problem: The ANA screening test is fraught with pitfalls, and if you have a way-high titer of U1-RNP on the tube test and symptoms / signs of mixed connective tissue disease (which is a rough thing) but ANA is negative, perhaps there's a problem with the substrate. Your physician will want to call the lab's pathologist -- he / she would be interested in knowing. Best wishes. ...Read more

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My lab tests came back with a positive ANA and positive rnp antibodies...Are these normal?

No.: Positive anas can be "false" positive. On the other hand an rnp antibody is not false. This combination would indicate mixed connective tissue disease. That having been said, I have many patients with a low titer rnp positivity and no signs of disease. ...Read more

Dr. Katharine Cox
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Rnp Antibody (Definition)

Http://www. Mayomedicallaboratories. Com/test-catalog/clinical+and+interpretive/81357. ...Read more