Doctor insights on:
Rnp Antibody (Overview)
My serum test is negative for endomysial antibody iga, ttg tissue transglutasminase iga, gliadin antibody igg. But positive for gliadin antibody iga?
Rnp Antibody (Overview)
Does it matter what the titre of rnp antibodies are when it is the only single one identified in diagnosing mixed connective tisseue disease?
No: The diagnosis of mctd must first be made if the history and physical examination are indicative of a possible connective tissue disease. If those elements are present and the disease seems to overlap between conditions such as lupus and polymyositis and others, it is reasonable to do laboratory testing. Only then, if the rnp is above the reference lab normal, it will confirm mctd. Rnp alone: no dx. ...Read more
Sm/rnp antibody- ANA choice- positive, speckled/titer: 1:1280; sm & rnp (done alone) negative; sm/rnp antibody (together?) positive 3.0 guessing mctd?
Heads up: One of the things that's frustrating about these antibody tests looking for different connective tissue diseases is that they are difficult to do and are fraught with pitfalls. I suspect you've had at least one lab error to complicate your workup. Have you have a tube test for u1-rnp? Your clinical symptoms and signs actually tell more about your diagnosis ; best direction for treatment. ...Read more
Ebv panel. Ebv nuc antigen igg=157, early ag igg=12.7, EBV VCA igg=112, EBV VCA igm=10.6. Please explain. Concerned about spleen. Symp=fatigue/fog?
? Active infection: It's impossible for me to answer with certainty since i don't know the normal ranges your lab uses. If early ag & vca igm are elevated above normal this indicates active ebv infection.I don't know if it is acute or chronic without knowing your history. If chronic i see that as a sign of poor immune function.Immune-boosting herbs/supplements & IV vit c drips may help, but find why immunity is poor. ...Read more
Pls interpret: HBsAG w/Titer 4548.07 Reactive. Anti HBS NONREACTIVE, HBeAG NONREACTIVE, Anti HBe REACTive, Anti HBc IgM NONREACTIVE?
Ebv capsid ab IgG 1:580. Positive ccp antibody igg, sed rate, high RDW and mpv on cbc.Liiver alt, AST elevated. Any ideas?
ANA 1:80 speckled, SM, RNP, SCL-70 detected.Leukocyte, urate, alkaline phosphate,creatinine low. Albumin, triglycerides high. Pos HAV, HBV. Rhem. Neg?
Not enough info: Lab tests need to be evaluated in the context of the clinical symptoms. You need this issue evaluated by a rheumatologist ...Read more
How about it?: Up to a quarter of women your age have an ANA (immunofluorescent antibody) at a low titer like yours with a speckled pattern. If there's a question of whether you have lupus or one of its relatives, it's a piece of information to note and file for future reference. A negative ANA would rule several things out. Your result proves nothing positive. Best wishes. ...Read more
I'm having negative DNA ,Sm and Rnp antibodies, but positive sm/rnp antibody,and high ANA titre speckled,so what is the diagnosis ?
Lupus: These serologies are rather non specific. The speckled ANA is non specific. In Systemic Lupus Erythematosis (SLE) it is usually homogeneous in its staining. Anti-Sm and Anti RNP can be see in mixed connective-tissue diseases and overlaps with SLE, scleroderma and myositis. As often is the case a specific diagnosis cannot be made. You need to see a Rheumatologist. ...Read more
Hiv ab,1/2, eia with relx result repeatedly reactive. HIV 1/2ab differentiation w/refl hiv1 antibody negative hiv2 antibody negative. pos or neg hiv?
It depends: In a situation like this you have one positive test and one negative test. The lab should run a tie-breaker test (HIV RNA) to give you a real answer. Also, the first test may be an older test 2nd or 3rd generation) instead of the latest 4th generation) test. It also depends on if you have flu-Like symptoms. Seek help from a specialist in HIV who can help you understand. ...Read more
Ebvab VCA IgM <36 (range 0-35.9), ebvearly antigenab IgG 37 (0-8.9), ebvab VCA IgG >600 (0-17.9), EBV nuclearantigenab IgG 409 (0-17.9) mono? No mono?
You had mono...: Your mono-like symptoms likely prompted the testing- i hope you are starting to feel a little better. Testing for different antibodies (igm and igg) against ebv, requires careful interpretation. In early phases of infection, the igm level peaks first followed by a decline; levels of igg peak afterwards, and may remain elevated for quite a while. ...Read more
Elevated EBV ab VCA IgG <8 and EBV nucleaer antigen ab IgG test 4.2. & anti-dna(ss)igg ab qn ( 119)& c react protien(5.6) what are implications?
Nothing.: Ebv antibodies indicate you had a previous infection, but not active. The c-reactive protein needs a units indicator - that is either normal or somewhat elevated. The anti ss dna is extremely nonspecific and very rarely indicated; I have no idea why that was ordered, discuss with your doctor. ...Read more
Monotest (target values <1.0=negativ). Values: EBV VCA IgG-Ak 39.9; EBV VCA IgM-Ak 1.1; EBNA-1 IgG-Ak 14.7; EBV DNA (PCR) negativ. What does it mean?
What would cause a high positive ANA (1:640) speckled, nucleolar with a low positive smooth muscle antibody (1:40) but negative SS-A, SS-B, anti-Smith, RNP, SCL-70, Anti Jo antibodies? Liver disease?
Probably normal: Many people have a positive ANA without being sick. If you also have elevated liver enzymes, a workup for autoimmune hepatitis may be continued, but if there's nothing to suggest a liver problem biochemically, I'd not be in a hurry to diagnose despite anti-smooth-muscle. ANA means nothing apart from the clinical picture. Best wishes. ...Read more
Rubella IgG: This means that you have been vaccinated for this infection. And, you are fully immune to it. There is nothing to worry about in regards to being pregnant. ...Read more
Reactivated EBV 9 months after first infection. Could i be immunodeficient? Antibody count: 65 ab VCA igm; 53 ea ab igg; 431 ab VCA igg; 289 ebna igg.
No: Unfortunately ebv stays alive forever in one's lymphocytes and can get activated easily in susceptible people without known immunodeficiency. However you may call that an immunodeficiency given that all people have been infected with it yet only few would have recurrent ebv problem. ...Read more