Doctor insights on:
Used for lymphoma: Rituxan (rituximab) was one of the first monoclonals to be used to treat lymphoma having failed chemo. Rituxan (rituximab) which is a mAb targeting CD20, a marker on lymphomas and normal WBC induces ADCC tumor kill on all cells with the markers. Patients manage since the normal WBC's are regenerated in the marrow from precursor cells so count remains normal. Marked improvement in survival of lymphoma now seen. ...Read more
Mostly infusion rxns: Rituxan is given intravenously slowly at first to look for common immediate reactions like chills, fever, shakes, itching, hives, headache all of which could be prevented or lessened by giving premedications like Benadryl (diphenhydramine) and steroids. Reactivation of hepatitis b, lowering resistance to infections, rapid destruction of tumor cells causing i'll effects to organs (tumor lysis) can also occur. ...Read more
Nhl grade 3a stage 1, 6 cycles of rchop-21 and igrt 30 gy taken. Is rituximab maintenace therapy required further?
Maintenance therapy: ...with rituximab is commonly given for follicular lymphoma, but not so much for other types of NHL (non-Hodgkins Lymphoma). Rituximab maintenance forestalls the the recurrence of the disease, but does not necessarily make patients live longer; because they could also wait and get rituximab a 2nd time when there disease relapses. ...Read moreSee 2 more doctor answers
TTP/rituximab: Twelve articles have reported 27 patients treated with Rituximab for ttp, with bene?t described in 25 (93%) of the patients. These observations from small uncontrolled case series is said to provide the background and rationale for a randomized clinical trial to establish the efficacy of Rituximab in this disease. ...Read moreSee 1 more doctor answer
Median half life 32d: The median half life of Rituxan (rituximab) is 32 days. It takes approximately 5 half-lives before a drug is considered "gone" from the system. Therefore a median time-period would be 160 days from completion of treatment. Remember measurement of drug in the system is not the same as the side-effect of the drug or the length of time the lymphocyte population is affected. ...Read more
Rituximab and obintzumab have been brought to my attention as medication that could be used in the treatment of my illness. Will they help me?
Need more info: Need to know what your illness is to comment on whether the treatment would help. ...Read more
Most likely.: What side effects do you speak of? Most side effects of Rituximab occur during the infusion itself; I have very few folks complain of anything afterwards except maybe fatigue (that is if they receive Rituximab by itself). It does suppress the b lymphocytes for months but usually that translates into nothing. Patients who have had heart pain or irregular heartbeats in the past may experience .Reed. ...Read moreSee 1 more doctor answer
- Talk to a doctor live online for free
- Rituxan allergy
- Is rituxan chemotherapy?
- Ask a doctor a question free online
- Rituxan rheumatisms medication
- Is hypersalivation a symptom with rituxan?
- Rituxan hemolytic anemia
- Side effects of rituxan
- Talk to an oncologist and hematologist online for free