Top
10
Doctor insights on: Rituxan Therapy

Share
1

1
Please tell me about rituxan (rituximab) therapy?

Please tell me about rituxan (rituximab) therapy?

Used for lymphoma: Rituxan (rituximab) was one of the first monoclonals to be used to treat lymphoma having failed chemo. Rituxan (rituximab) which is a mAb targeting CD20, a marker on lymphomas and normal WBC induces ADCC tumor kill on all cells with the markers. Patients manage since the normal WBC's are regenerated in the marrow from precursor cells so count remains normal. Marked improvement in survival of lymphoma now seen. ...Read more

Dr. Melissa Gowans
70 doctors shared insights

Rituxan (Definition)

Rituxan is an antibody based agent which is a kind of ...Read more


2

2
Any side effects from rituxan (rituximab) therapy?

Mostly infusion rxns: Rituxan is given intravenously slowly at first to look for common immediate reactions like chills, fever, shakes, itching, hives, headache all of which could be prevented or lessened by giving premedications like Benadryl (diphenhydramine) and steroids. Reactivation of hepatitis b, lowering resistance to infections, rapid destruction of tumor cells causing i'll effects to organs (tumor lysis) can also occur. ...Read more

3

3
Will doing mantainence therapy on rituxan, (rituximab) buy a little more time?

What disease?: Rituxan (rituximab) is a treatment for many diseases. Which disease are you referring to and what do you mean by buy you more time? ...Read more

4

4
Nhl grade 3a stage 1, 6 cycles of rchop-21 and igrt 30 gy taken. Is rituximab maintenace therapy required further?

Maintenance therapy: ...with rituximab is commonly given for follicular lymphoma, but not so much for other types of NHL (non-Hodgkins Lymphoma). Rituximab maintenance forestalls the the recurrence of the disease, but does not necessarily make patients live longer; because they could also wait and get rituximab a 2nd time when there disease relapses. ...Read more

See 2 more doctor answers
5

5
Chance of ttp relapse while having/had rituximab therapy?

TTP/rituximab: Twelve articles have reported 27 patients treated with Rituximab for ttp, with bene?t described in 25 (93%) of the patients. These observations from small uncontrolled case series is said to provide the background and rationale for a randomized clinical trial to establish the efficacy of Rituximab in this disease. ...Read more

See 1 more doctor answer
7

7
How long after treatment with rituxan (rituximab) will the effects go away?

How long after treatment with rituxan (rituximab) will the effects go away?

Median half life 32d: The median half life of Rituxan (rituximab) is 32 days. It takes approximately 5 half-lives before a drug is considered "gone" from the system. Therefore a median time-period would be 160 days from completion of treatment. Remember measurement of drug in the system is not the same as the side-effect of the drug or the length of time the lymphocyte population is affected. ...Read more

9

9
How effective is the 'rituximab' treatment for nephrotic syndrome?

Rituximab: In an article at this link: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358759/, the article suggests that Rituximab is not effective in forms of INS resistant to steroids and calcineurin inhibitors. Ask the physician treating the patient for more information. Good luck. ...Read more

10

10
How long after rituxan (rituximab) treatment will the side effects go away?

How long after rituxan (rituximab) treatment will the side effects go away?

Most likely.: What side effects do you speak of? Most side effects of Rituximab occur during the infusion itself; I have very few folks complain of anything afterwards except maybe fatigue (that is if they receive Rituximab by itself). It does suppress the b lymphocytes for months but usually that translates into nothing. Patients who have had heart pain or irregular heartbeats in the past may experience .Reed. ...Read more

See 1 more doctor answer
Dr. Robert Lowe
66 doctors shared insights

Rituximab (Definition)

Rituximab ...Read more