Doctor insights on:
Ribavirin For Hepatitis C
Depends: That depends on which genotype of hcv you have. In general, it's easier to cure hepatitis c with a combination of interferon, ribavirin, and an hcv protease inhibitor than with interferon and Ribavirin alone. However, there are some hcv genotypes that have a high cure rate without the protease inhibitor. ...Read more
What are relapse symptoms after triple therapy(ribavirin, peg-interferon, incivek) for hepatitis c? Very worried about relapsing at the moment!
AVOID: Yes. Avoid anyone recommending such treatment in 2014. This is outdated, not very effective, and CURE is now possible in nearly 100% of the cases with the more appropriate medications available today. Please get to a Hep C treater/specialist for the best outcome. ...Read moreSee 1 more doctor answer
New medication, TTYD: According to Gilead (maker of Solvadi), in their POSITRON trial, 61% of all pts with Type 3 HepC had a sustained virologic response (SVR) (lower Hep C virus blood counts) at 24 wks. See the package insert (PI) approved by the FDA: https://www.gilead.com/~/media/Files/pdfs/medicines/liver-disease/sovaldi/sovaldi_pi.pdf. In the trial, those w/o cirrhosis were 68% likely to have SVR. TTYD about this. ...Read more
I'm hcv+ geno typ3, my weight is 54 kg, hb is 13.8, i'm taking ribavirin 400mg bid with sovaldi, is it ok or should I take 500mg bid.plz advise.Thanks?
Normal dose: 400 mg 2 times a day is the standard dose. It comes in 200 mg doses so would be hard to get 500 anyways. The best thing to do is ask your doctor. I would follow that advice myself. ...Read more
Five months into combo tx for hep c. Now I have a nasty ribavirin rash on my body. What can I do to relieve the incessant itching and weeping rash?
Treatment rash?: If you are taking a triple drug regimen for hepatitis c with interferon, ribavirin, and telaprevir then the rash is probably related to the third agent. However, what you are describing sounds generalized and severe, and at risk for secondary infection. Some rashes, like stevens-johnson eruptions, can even be life-threatening. Make sure you seek medical attention as soon as possible. ...Read more
Hep c: Do you have to be on treatment now? By the end of this year ribaviran will most likely no longer be used to treat hep vc. Treatments will be more effective and shorter in duration. Ribaviran is not directly active against hep c like sofosbuvir and the other amazing drugs coming this year. ...Read more
Sovaldi + ribavirin: Sovaldi (sofosbuvir) is a uridine nucleotide analog prodrug that is converted in liver to an active metabolite that inhibits the hcv ns5b rna-dependent RNA polymerase, which is essential for viral replication. The combination is fda-approved, forms an aasld/idsa recommended treatment arm for multiple genotypes, as well as for hcv/hiv coinfected patients, ; those with liver cancer pre-transplant. ...Read more
I have beta-thalassemia and HCV. I was on interferon with ribavirin in 2008. It didn't work. Now I want to try Sovaldi. What are my chances it works?
Worth the try: It's looking really good. I hope you are able to get it. The politics of availability are bizarre -- I feel the drug company needs to see a fair profit that will allow more work, and that the people whose taxes paid for the basic research aren't denied a great medicine. Keep reading the blogs and find out the best way for you to get access to the real stuff at reasonable cost. ...Read moreSee 1 more doctor answer
Hi,Can I start taking iberet folic after my sovaldi and ribavirin treatment or how long should I wait.I'm 38 F and started med at early stage of hcv.
Folic acid: This question is best answered by the specialist who put you on this combination. I also recommend that you consult your pharmacist who has access to such information. ...Read more
My boyfriend was on Salvadi and ribavirin for hep c and 1 month after he finished treatment I got pregnant. What do I need to know about side effects?
None,that we know of: The truth is we have no idea what effect it may have had on his sperm. But we do know that on average it takes sperm 105 or so days to come to maturity. That said, any sperm that would have gotten you pregnant were exposed to those drugs during their development. ...Read moreSee 2 more doctor answers