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Doctor insights on: Rhogam Shot After Miscarriage

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What happens if I don't get a rhogam shot after miscarriage?

What happens if I don't get a rhogam shot after miscarriage?

RhoGAM: If your blood type is negative, and don't receive the rhogam, you may reject the next fetus, if you become pregnant with a blood type positive baby (if your partner is blood type positive). ...Read more

Dr. Seth Derman
512 Doctors shared insights

Miscarriage (Definition)

A "lay" term for early pregnancy loss usually prior to the second trimester. Physician's use the term "spontaneous abortion" to describe these events, but the word "abortion" in lay use has come to connote only ...Read more


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No rhogam shot after miscarriage in 2006. Just had a miscarriage at 13 weeks in nov. 2012. O neg. Bloodtype. Could this be related to not receiving shot?

No rhogam shot after miscarriage in 2006. Just had a miscarriage at 13 weeks in nov. 2012. O neg. Bloodtype. Could this be related to not receiving shot?

Unlikely: This is an unlikely cause. However, there are blood tests the doc can run on you to see if you have been sensitized in any way to the rh factor due to that earlier event. It is a test that is often performed early in pregnancy, so it may have been part of your 2nd pregnancy workup but never discussed (if it was negative). ...Read more

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I recieved rhogam shot after a miscarriage at 5 wks last tues because I am o-. Not ready to try and conceive. How soon can start birth control pills?

I recieved rhogam shot after a miscarriage at 5 wks last tues because I am o-. Not ready to try and conceive. How soon can start birth control pills?

Need a neg preg test: I'm sorry you miscarried.

you may start birth control as soon as you have a negative pregnancy test. That may be as soon as 2 weeks after a miscarriage. Ask your doctor for a blood test or a urine test. ...Read more

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I had a rhogam shot when I found out I was pregnant I miscarried, do I need another rhogam?

I had a rhogam shot when I found out I was pregnant I miscarried, do I need another rhogam?

Yes: You need another shot as you may have been exposed to significant blood from your baby and if that baby was rh+ you have a risk of developing rh antibodies. ...Read more

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Had 2 miscarriages since my last rhogam shot think I may be preg again do I need the shot or is it too late?

Had 2 miscarriages since my last rhogam shot think I may be preg again do I need the shot or is it too late?

Probably not: You should be evaluated for the need for Rhogam anytime you bleed during a pregnancy. At this time, you need to have a test for Rh antibodies that is standard with your first OB labs. If it is negative, you would only need Rhogam in early pregnancy if you bleed. You would then get a Rhogam shot at about 28 weeks routinely. See your OB. ...Read more

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Will getting the rhogam shot help with the next pregnancy if I've previously had two miscarriages?

Will getting the rhogam shot help with the next pregnancy if I've previously had two miscarriages?

Rhogam: If you are Rh Negative, then rhogam is indicated by 2nd trimester to decrease the risk of inducing red blood cells break down (hemolysis) in the fetus. Close follow up with maternal fetal medicine (high risk pregnancy) specialist will be needed. ...Read more

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Miscarriage in Jan. Now 6 months. Got the rhogam shot when I miscarried. Dr. said I will get 1 at 28w, birth. Is that fine or should've had 1 earlier?

Miscarriage in Jan. Now 6 months. Got the rhogam shot when I miscarried. Dr. said I will get 1 at 28w, birth. Is that fine or should've had 1 earlier?

That's fine: Your doctor is right, you would get one earlier if any other problem like bleeding or so, but otherwise with stable pregnancy that would be the routine, wish you a healthy pregnancy and a healthy baby ...Read more

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When is the latest I can get rhogam shot? I received one when I miscarried does that protect this baby too?

No it doesn't: Rhogam should be given to Rh negative ladies within 72 hours of any obstetric complication or fetomaternal hemorrhage risk, e.g. abortion, miscarriage, ectopic pregnancy, CVS, amniocentesis. Prophylactic at 28 weeks pregnancy, and within 72 hours of delivery. One shot doesn't provide long lasting immunity, this is kind of passive not active immunization, as there is no microbe to immunize against ...Read more

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If I suffered a miscarriage without a rhogam shot, what happens if I get pregnant again?

If I suffered a miscarriage without a rhogam shot, what happens if I get pregnant again?

Rhogam: If you are rh positive there is no problem and Rhogam is not indicated. If you are rh negative there is a potential chance that you will get sensitized depending on whether you get transfused a certain amount of blood from a rh positive miscarriage. ...Read more

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I am rh- and after my miscarriage I did not recieve the rhogam shot, will I ever be able to carry a baby to term?

I am rh- and after my miscarriage I did not recieve the rhogam shot, will I ever be able to carry a baby to term?

Get tested: Only a small percentage of rh negative women will develop antibodies to the rh protein after a miscarriage. Ask your doctor or midwife to test you with an antibody screen to see if you have any antibodies. Even if you did develop antibodies the chances would be very good that your next pregnancy would be relatively normal. ...Read more

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I'm rh-. Had miscarriage on Sat. Lots of bleeding. Took preg test it was negative. I took rhogam shot Monday. Not sure if past 72 hr mark. Too late?

Unclear: It is not clear what is going here. If you took a pregnancy test right after a miscarriage then the test would still be positive to some degree. The doctor treating your miscarriage can clarify what happened and clear up the timing of the Rhogam shot. ...Read more

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Rh- I Had a Miscarriage I got the rhogam shot then now I am 28w I haven't received it yet for this pregnancy Is it safe to get it after 28w? Scared

Strict time line: There is a strict time line for the administration of rhogam. If it is not given at 28 weeks, the potential beneficial effect may be diminished or there may be no benefit at all. ...Read more

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I had a miscarriage and received a RhogAm shot because I am rh negative. 12 days later I had a positive ANA (1:160). Could RhogAm cause a false +?

I had a miscarriage and received a RhogAm shot because I am rh negative. 12 days later I had a positive ANA (1:160). Could RhogAm cause a false +?

ANA titer: Since "Rhogam" contains antibodies in the gamma globulin administered in the Rhogam shot, it is possible for antibodies contained within to reflect a positive "ANA titer". This does not affect the potential for diseases associated with a positive titer for ANA. ...Read more

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I had miscarriage a year ago and never received a rhogam shot. I have A- blood and hubby is A+. Will I be able to conceive again or do I need the shot?

I had miscarriage a year ago and never received a rhogam shot. I have A- blood and hubby is A+. Will I be able to conceive again or do I need the shot?

OK to conceive again: If you were to have any problems after the miscarriage it would have already happened. When you get pregnant it will be necessary to receive the injection during the pregnancy and or after delivery to protect you from a blood reaction. You will be fine. The Rhogam is to protect you from the babies blood should you be exposed during delivery. Good luck with your new family. ...Read more

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Rhogam shot for miscarriage. Will this protect my future babies from harm until 28 weeks of pregnancy?

Rhogam shot for miscarriage. Will this protect my future babies from harm until 28 weeks of pregnancy?

Should do: Good that you took it after miscarriage, within the timeframe, once pregnant again, please have good prenatal care from day one, good luck ...Read more

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Had miscarriage at 6w3d. On 4/2/13. Have a neg. Blood. Er/urgent care docs did not give rhogam shot. Is it needed? Not sure of hubby's Rh factor.

Had miscarriage at 6w3d. On 4/2/13. Have a neg. Blood. Er/urgent care docs did not give rhogam shot. Is it needed? Not sure of hubby's Rh factor.

You need it soon: 85% of people have rh+ blood, so playing the laws of averages, there is a very strong likelihood that the father was rh+. There is always the chance that the baby would have been rh- and Rhogam wouldn't be necessary, but why take the chance. It's to prevent a problem with future pregnancies. ...Read more

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I have pcos, and I think I might be pregnant, if I am. Should I get another rhogam shot since I'm ab-. I had a miscarriage @ 6wks last year?

I have pcos, and I think I might be pregnant, if I am. Should I get another rhogam shot since I'm ab-. I had a miscarriage @ 6wks last year?

First take test: If you think you might be pregnant check then check a home pregnancy test. They are cheap, reliable and available at any pharmacy. This is the first step. Since you are rh negative you will need a Rhogam shot if you have bleeding and when you are 28 weeks pregnant. You do not need to do one simply because you in early pregnancy. Our office is near you and we would love to help you out if you need. ...Read more

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8weeks preg, Rh negative, red bleeding and cramp, could it be miscarriage, do I need anti d rhogam shot as b4 12 weeks?

8weeks preg, Rh negative, red bleeding and cramp, could it be miscarriage, do I need anti d rhogam shot as b4 12 weeks?

Yes: It could be a miscarriage, but it could just as well be associated with implantation/expansion of the placenta. You still need rhogam, but you can have mini-rhogam which is 50 micrograms (vs 300micrograms in standard dose). ...Read more

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I am o negative and had a miscarriage, but never went to the doctor or told anyone other than my husband. Now that I understand what it means to be Rh negative I am worried because I am 26 weeks pregnant. My doctor plans to give me the rhogam shot at 28 w

Please inform OB: You need to be up front with your OB in this matter so appropriate surveillance testing can be done during pregnancy. There is a possibility you were not sensitized during the first pregnancy but I wouldn't count on it. If testing shows the baby starting to have problems they can proceed with treatment. ...Read more

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I don't think I got my rhogam shot after last delivery of 3rd child (did w previous 2 births). Now pregnant again. Will I miscarry baby?!

I don't think I got my rhogam shot after last delivery of 3rd child (did w previous 2 births). Now pregnant again. Will I miscarry baby?!

Unlikely: If you miscarry, it is likely not related to the Rh problem. Usually the first pregnancy after a missed Rhogam results in fairly mildly hemolytic disease, but subsequent pregnancies have increased likelihood of hydrops. Be sure your OB is aware of your situation, and your baby will be monitored carefully. Your baby may need phototherapy or exchange transfusion after birth. ...Read more

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Rh neg. Had miscarriage got the rhogam. Pregnant now What will happen if I don't get the shot until after delivery as long as I have no bleeding?

Rh neg. Had miscarriage got the rhogam. Pregnant now What will happen if I don't get the shot until after delivery as long as I have no bleeding?

Not good: It is the standard of care to administer Rhogam at 28 weeks gestation. Unless you bleed, you will probably not be exposed to the baby's blood until you give birth. However, large amounts of the baby's blood often leak into the mother during delivery. If the baby is Rh +, that results in the formation of antibodies in the mother. This is dangerous for subsequent Rh + pregnancies. ...Read more

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If I don't get the rhogam shot what will happen?

Risk for future baby: Rhogam is supposed to prevent you from developing anti d antibodies that could cause serious problems for future babies/fetuses. Those problems include: anemia, jaundice, hydrops fetalis, death. This risk is greater if we know for sure that product of current pregnancy had blood type rh positive and there was significant transfer of fetal blood into your body. You should discuss it with your doc. ...Read more

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How much thimerosal is in the Rhogam shot?

No mercury in Rhogam: April 16, 2001, the FDA approved production of RhoGAM without thimerosal and the company agreed to distribute only product without the preservative. (source: FDA. Gov) ...Read more

Dr. Gerard Honore
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Pregnancy Loss (Definition)

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Dr. Robert Bates jr.
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Rho Immune Globulin (Definition)

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