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Rh Induced Hemolytic Disease Of The Newborn
Different blood type: Hemolytic disease of newborn is caused by different blood types in mom and baby. Classically, mom is rh negative (a- or o-, etc). The baby is rh positive. Mom then make rh antibodies that cross over to the baby and cause breakdown of the red blood cells. This can make the baby very sick. ...Read moreSee 1 more doctor answer
Depends on form: Decades ago when i started rh hemolytic disease was often fatal during pregnancy & problamatic in newborns. Surviving infants often needed many exchange transfusions & had worrisome futures. Then a treatment called Rhogam came along & has ended that nightmare. In 26 yrs, I have transfused 1-2 ABO babies primarily for late stage anemia but had no fatalities. Rh disease is a problem without rx. ...Read more
Does the possibility of an unborn baby getting antibodies c&d, (hemolytic disease of the newborn) increase with each pregnancy?
Yes: Hemolytic disease of the newborn, causing yellow skin and eyes (jaundice) with anemia, is most commonly due to a "set-up"--a blood type difference between mother and child. Blood types are caused by genes at the ABO and other loci (rhesus being most damaging), with o type or rh negative moms making antibodies to red blood cells of a or b or rh+ fetuses (if mom is o and fetus ab, baby switched), . ...Read more
Test for mom/baby: The baby will get test like coombs testing, hemoglobin or cbc, bilirubin tests and reticule yet counts. The coombs tests shows that an antibody is cause the hemolysis. The antibody specificity can be determined by additional tests. These antibody levels can be measured in mom and baby. Most of these antibodies will cause hemolysis. Some can cause decreased RBC production in the baby. ...Read moreSee 1 more doctor answer
Jaundice and anemia: Hemolytic disease of the newborn (hdn) may develop when a mother and her unborn baby have different blood types. The mother produces substances called antibodies that attack the developing baby's red blood cells. The most common form of hdn is ABO incompatibility, which is usually not very severe. The least common form is rh incompatibility, which can be very severe, but can be prevented. ...Read moreSee 1 more doctor answer
HDN: The process of hemolytic disease of the newborn (HDN) starts soon after birth, however the symptoms (mainly jaundice) may not be detected if clinicians do not maintain a high index of suspicion. HDN due to Rh incompatibility is very rare in the US, but ABO incompatibility should be suspected whenever the mother has type O blood and the baby has either type A or B blood and there jaundice. ...Read moreSee 1 more doctor answer
Various: Hemolytc disease can be mild and treated with bili lights. In extreme cases, it may be picked up early in pregnancy from an antibody screen. If positive, the antibody is identified. If a concerning antibodies present, the blood counts of the baby will be followed closely. Intrauterine transfusions may be required in these rare instances. ...Read moreSee 1 more doctor answer
Bacterial in PLT: Transfusion is safer today than ever, but as any other intervention in medicine has risks associated with it. The infectious disease most commonly associated with transfusion is bacterial contamination in platelet components about 1 in 12, 000 transfusions. To put it in perspective HIV is about 1 in 2 million. The most common adverse event (1%) is fever and hives along with volume overload (taco). ...Read more
Depends: A screening test is a relatively simple & inexpensive test designed to narrow down the number of patients brought in for the more expensive specific tests. For every 10, 000 screened, 100 may show positive & secondary tests will show 2--3 with a real problem. The screen eliminated 99% that didn't need a specific test.The state notifies me of + screens & we get the tests.If a real pbm, rx is atarted. ...Read more
HgbE beta thal: Your infant may be developing hypersplenism. See a pediatric hemotologist for help. ...Read more
What are the long-term health effects of blood group incompatibility (rh or ABO problems) post transfusion?
Only Rh: If there is no immediate adverse reaction to ABO incompatible transfusion, there are no long term effects. For Rh mismatch, it could result in developing antibody to Rh that would cause transfusion reactions in the future if given Rh positive blood to a Rh negative person if s/he received Rh positive blood. It could also put the Rh positive fetus of the Rh negative woman at risk. ...Read more
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