Doctor insights on:
Retinol Birth Defects
It WILL cause defect: "The baseline population risk of malformations is 3-5%, but it increases to almost 30% in women exposed to isotretinoin during the first trimester of pregnancy." see http://www.ncbi.nlm.nih.gov/pubmed/19961047 Many are profound, horrible defects--absent ears, tiny brain, deafness and blindness. Effects may occur many months after a woman ceases taking it. ...Read moreSee 1 more doctor answer
Vitamin A helps form and maintain healthy teeth, skeletal and soft tissue, mucous membranes, and skin. It is also known as retinol because it produces the pigments in the retina of the eye. Vitamin A promotes good vision, especially in low light. It may also be needed ...Read more
Yes: Here is a primer on the terms congenital refers to being present at birth. Anomalies, abnormalities, defects are often used interchangeably. Not all are genetic or familial. Malformation and deformation mean different things. Malformation is an anomaly due to abnormal formation of a structure. Deformation is a change in a structure due to forces like pressure, eg, in cases of low amniotic fluid. ...Read moreSee 4 more doctor answers
Take vitamins: Folic acid is almost always included in prenatal vitamins because most pregnant women don't get enough of it from just what they eat. Taking folic acid for at least one month prior to conception lowers the risk of neural-tube defects, such as spina bifida, significantly. Recommended dose is 400 micrograms of folic acid every day prior to pregnancy and 600 micrograms when pregnant. ...Read moreSee 1 more doctor answer
Any drug causing: birth defects is separate from taking a supplement to support neurological development in pregnancy. Most supplements don't and aren't designed to prevent against birth defects. If you are concerned about this, discuss it with your OB/GYN doctor, and get a full evaluation of what you're taking, and what your concerns are. So, you can have piece of mind. Taking too much folic acid is not wise too. ...Read more
None: The hormones in birth control pills, or Progesterone shots ("depo provera") are not thought to cause birth defects. Many women inadvertently take birth control after they have already conceived and their children do not seem to have any increased risk of birth defects. ...Read moreSee 1 more doctor answer
Nope.: Genetic prenatal testing can detect many chromosomal or microscopic dna defects - but it cannot prevent birth defects! 2-4% of all newborns will have a minor or major birth defect and the vast majority of those have unknown genetic underpinnings at this time, although many of us are working to change that. Take Folic Acid 1-5 mg daily to prevent 75-95% of major neural/cardiac fetal anomalies! ...Read moreSee 2 more doctor answers
Possibly: It depends on multiple factors. There are different degrees of neural tube defects. Some people can have a mild defect and other may have a severe defect. It also depends on the location of the defect. Your doctor might be able to better answer this question with all of the relevant information. ...Read more
Yes: Some can, but not all. Taking Folic Acid supplements before conception can prevent spinal cord defects. Excellent sugar control for a diabetic, avoiding certain drugs or medications early in pregnancy, and being aware of higher risks with advancing maternal age are all important. ...Read moreSee 2 more doctor answers
Do Topical retinoids (Antiaging creams mostly retinoids) cause birth defects during pregnancy? Asking about topical not systemic?
No: External creams and lotions do not penetrate the skin deep enough to enter the blood. For any medication to affect the fetus, it must enter the blood that can go to the fetus. ...Read more
Several types: Major congenital malformations include: spina bifida or heart defects. Other important ones include cleft lip or cleft palate. More subtle, but still important ones include effects on learning and cognition during childhood. Not all anticonvulsants do theses things to the same degree. The total daily dose often helps to determine the frequency of these defects. ...Read moreSee 2 more doctor answers
Benzodiazepines cause birth defects according to research. Which specific birth defects do they cause?
Cleft lip/palate: A recent British medical Journal did an extensive meta-analysis of all the major studies in benzodiazepines and found a slightly increased risk, about 1.79 x greater risk of cleft lip and palate than the general population...no other major malformations reached clinical significance ...Read more