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Doctor insights on: Reticulocyte Count Sickle Cell

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Does high reticulocyte count mean sickle cell crisis?

Not necessarily....: Patients with sickle cell disease have elevated reticulocyte counts at baseline, as their red cells have significantly reduced half lives relative to normal rbcs. More rapid red cell synthesis, reflected by the high retic count, is needed to maintain steady state, albeit lower than normal. Are you having other symptoms suggesting vaso occlusive crisis? If so, you should seek medical attention. Read more

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Dr. Tipu Sultan
65 Doctors shared insights

Reticulocyte Count (Definition)

"young" red blood cells. They have just emerged from the bm into the circulation. They tend to be larger and slightly purple on the smear. A special stain can be done to make them stand out and the lab can count them. This is usually a sign of a robust production of rbcs and therefore good news. Especially if the patient is recovering from blood loss or ...Read more


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Is sickle cell anemia painful?

Is sickle cell anemia painful?

Pain crisis=painful: Sickle cell anemia itself is not painful. However sickle cell anemia can be complicated with crisis episode either in a form of sickle cell pain crisis (this is painful), or other episode such as acute chest syndrome, stroke etc. Read more

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Can I have sickle cell anemia?

Anyone can...: It would be unlikely that would could reach the age of 46 and not be diagnosed with sickle cell anemia. If you are truly concerned, testing is very easy. Read more

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Is sickle cell anemia hereditary?

Is sickle cell anemia hereditary?

Yes.: It is an autosomal recessive disorder, meaning that both parents must be carriers of the mutation. If they are, the chance of each child being affected is 1 in 4. Read more

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Why is sickle cell anemia painful?

Why is sickle cell anemia painful?

Poor circulation: In sickle cell disease red cell stick together and block circulation to extremity and other organ so it cause pain crisis. Read more

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How is sickle cell anemia detected?

Blood test: Every newborn baby undergoes "newborn screening" test before they are released from hospital. Most of abnormal hemoglobins, e.g. Hemoglobin s in sickle cell disease, are detected. Read more

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How dangerous is sickle cell anemia?

More info needed: Patients with sickle cell anemia have greater tendency for severe anemia and infection. Usually children have more difficulties. Sometimes frequent transfusion is needed to assist in crises, or to suppress sickle hemoglobin and decrease sickling issues which can be very painful. Hydroxyurea is used to help symptoms and to increase fetal hemoglobin, vaccinations, and antibiotics help. See MD. Read more

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What are the tests for sickle cell anemia?

What are the tests for sickle cell anemia?

Hb electrophoresis: CBC and hemoglobin electrophoresis have to be done -at least- to make a diagnosis of sickle cell anemia. Read more

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What is the symptoms of sickle cell anemia?

Anemia, pain, crises: The most frequent presenting signs/symptoms of sickle cell include anemia and typical sickle cell crises which include pain crises (severe pain in arms, legs, shoulders, back), acute chest crisis (shortness of breath, cough, fever, lung infiltrate), dactylitis (pain toes/fingers usually as a toddler) and others.
Most patients that have sickle cell trait are completely asymptomatic. Read more

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What kind of disorder is sickle cell anemia?

What kind of disorder is sickle cell anemia?

Genetic: With ss disease a genetic mutation changes the gene sequencing needed for normal hemoglobin production. The alteration changes the way the hemoglobin handles the oxygen molecule as it carries it in the blood. The blood cell then becomes distorted in the small capillaries and the spleen. The cell breaks down rapidly and or remains trapped.Anemia is a chronic problem. Read more

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What is the 'reverse' of sickle cell anemia?

What is the 'reverse' of sickle cell anemia?

None: Sicle cell anemia is an inherent disorder of the red blood cell. The reverse woould be normal blood cells. Read more

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What makes sickle cell anemia so significant?

Chronic disease: Sickle cell disease is so significant in that it is a chronic disease that affects almost every organ. Like diabetes, the effects of sickle cell, crises, and transfusions can permanently affect the heart, the kidneys, the liver, the lungs, and the brain. Read more

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What are the symptoms of sickle cell anemia like?

What are the symptoms of sickle cell anemia like?

Pain.: When red cells sickle, they become rigid and block the flow of blood. If this happens in muscle or bone, the result is pain. In the lung it's pain and shortness of breath. In the brain, it can cause a stroke. Any organ can be effected. A painful crisis happens when blood flow is interrupted. They are episodic and unpredictable. Read more

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What are the different types of sickle cell anemia?

What are the different types of sickle cell anemia?

Types os SIckle Cell: From nih, division of blood diseases and resources:

sickle cell disease-ss: 65% of us patients; genotype s/s

sickle cell disease-sc: 25% of us patients; genotype s/c

sickle cell disease-s beta + thalassemia: 8% of us patients; genotype betas/ beta + thalassemia

sickle cell disease-s beta 0 thalassemia: 2% of us patients; genotype betas/ beta 0 thalassemia. Read more

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What are the reasons for painful crises in sickle cell anemia?

What are the reasons for painful crises in sickle cell anemia?

Vasoocclusive event: Episodes of pain are the most common type of vasoocclusive event. Pain may be precipitated by events such as weather conditions, e, g, high wind speed, low humidity, dehydration, infection, stress, menses, alcohol consumption, and nocturnal hypoxemia. However, the majority of painful episodes have no identifiable cause. Read more

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Is sickle cell anemia contagious?

No: Sickle cell anemia is not an infection - thus it is not contagious. It is a genetic disease and so, it is hereditary. Read more

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Dr. James Ball
355 Doctors shared insights

Sickle Cell Disease (Definition)

A group of disorders that cause red blood cells to become ...Read more