Doctor insights on:
Reticulocyte Count In Sickle Cell Crisis
Not necessarily....: Patients with sickle cell disease have elevated reticulocyte counts at baseline, as their red cells have significantly reduced half lives relative to normal rbcs. More rapid red cell synthesis, reflected by the high retic count, is needed to maintain steady state, albeit lower than normal. Are you having other symptoms suggesting vaso occlusive crisis? If so, you should seek medical attention. ...Read more
"young" red blood cells. They have just emerged from the bm into the circulation. They tend to be larger and slightly purple on the smear. A special stain can be done to make them stand out and the lab can count them. This is usually a sign of a robust production of rbcs and therefore good news. Especially if the patient is recovering from blood loss or ...Read more
Supportive care: It depends--sickle cell crisis can manifest as pain crisis, acute chest syndrome, stroke, priapism etc. But basically supportive care like- vigorous hydration, pain medication, adequate oxygenation, are needed. Exchange transfusion vs simple transfusion often times also has to be done depending on the level of hb. ...Read more
I recently was admitted for a sickle cell crisis and the pain in my shoulder has gotten worst. I have avn in that shoulder what are my options?
Ortho eval: Sickle crisis can certainly impact on pain levels. As the initial answer said you need an orthopedic evaluation. I am in the atlanta area, send me a private message and I will share some possible doctors for you to see. ...Read more
I don't think you can: Sickle cell crisis only happens if you have a diagnosis of sickle cell anemia. The degree of anemia sometimes is not that severe-however you will have anemia if you have sickle cell disease - not just a trait. If you only have a sickle cell trait -you will not have a sickle cell crisis. ...Read more
Usually pain.: There are several kinds of crises - pain or vaso-occlusive crisis (blood flow to an area is "clogged" by sickled cells leading to areas of cell death), splenic sequestration crisis (trapping of large volume of blood in the spleen), and aplastic crisis (life-threatening anemia caused by inability to make enough new red blood cells to keep up with the very short life span of sickled red cells). ...Read more
Not typically: If you have the sickle cell trait, it is possible to have an anemic crisis in the setting of severe dehydration or stress to the immune system, though this is rare. In most cases, individuals with the sickle cell trait live perfectly healthy lives. Remaining hydrated especially in the setting of physical activity and excessive heat should help to prevent any symptoms. ...Read more
PAIN WITH SICKLECELL: Sickle cell disese is a painful conditon and can have hemolytic crises, sequestration and thrombotic crises. The thrombotic crises is the one which causes the pain in any part of the body. They can be extremely painful requiring narcotics and some times have to be admitted to the hospital for IV fluids and pain medications. ...Read more
Do your homework: This site is not a shortcut for you to have your nursing school or health class assignments answered. If you plan to pursue these interests you need to review the course materials and answer in the phraseology and terms common to those sources. Otherwise the instructors will know you did not, and will treat your answers accordingly. ...Read more
Most less severe: Most are less severe in sickle cell thalassemia, but depends. HbS/B (0)thal: similar to HbSS in severity maybe slightly less severe. HbS/B (+)thal: has 60% HbSS and 30% HbA, thus less severe than HbSS (sickle cell alone). HbS/A-thal: less severe than HbSS due to decreased HbSS amount. ...Read more
Yes: There are different types of crisis in sickle cell. Untreated aplastic crises can cause death to to severe anemia. Untreated acute chest syndrome can cause death due to respiratory failure. Untreated splenic sequestration can cause death due to severe anemia. I would recommend not ignoring any crisis id sickle cell. ...Read more
How long does a sickle cell crisis last. In what is the best home remedies to keep her comfortable?
There are none!: This is one of the most painful things that can happen to a person, and it can result in lost/damaged organs and worse. If she is having a sickle crisis, get to a hospital for management. ...Read more
Can you have a sickle cell crisis in a tooth? My dentist states she does not see the cause of my pain in my lower back tooth on the right side.
Yes: Women with sickle cell disease who become pregnant are at higher risk for complications such as miscarriage, premature birth, and low birth weight. Sickle cell disease symptoms often worsen during pregnancy and pain crises become more frequent. However, with careful prenatal care and monitoring, serious problems can be avoided. ...Read more
I am curious as to the reticulocyte values obtained in patients with Sickle Cell Anemia. I am a laboratory worker so I see these quite often. Unfortun?
What about them?: They are always high as sickle cells do not last so long as normals. If low. Aplastic crisis. If vey high, hemolysis is increased. ...Read more
Pain.: When red cells sickle, they become rigid and block the flow of blood. If this happens in muscle or bone, the result is pain. In the lung it's pain and shortness of breath. In the brain, it can cause a stroke. Any organ can be effected. A painful crisis happens when blood flow is interrupted. They are episodic and unpredictable. ...Read more
Is anemia always present in sickle cell anemia? And for how long can I experience pain without this being a crisis for sickle cell?
They call it sickle: Cell anemia because, indeed, patients essentially all have anemia. The anemia actually improves the rheologic (flow) properties of blood in these patients, whose rbcs are otherwise rigid with reduced degrees of freedom for deformability. Sickle cell pain occurs due to microvascular occlusion and tissue compromise. Oral opiates/ nsaids may provide relief, but IV opiates may be needed (pain crisis). ...Read more
Sickle cell anemia: Good hydraion and good control/follow up wi your docor for your sickle cell are important. Your risk obviously will depend on the type of sickle cell anemia, the severity and your compliance to the therapy given for your sickle cell anemia. D/w your md and follow the recommendation. In general, need to keep good hydration, oxygenation. Take your Hydrea (hydroxyurea) as recommended and f/u with your doctor. ...Read more
Hello, I have sickle cell anemia, my hematologist recomended me to do splenectomy does it help to reduce pain crisis?
Puzzling: Most sickle cell patients have auto splenectomy. If you have scd then that is usual. Seek additional input ...Read more
In sickle cell crisis there is both reduced production of red cells and excessive destruction of red cells.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex, if you have sex. ...Read more