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Doctor insights on: Reticulin Antibody

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Discuss monoclonal antibody production?

Discuss monoclonal antibody production?

Monospecific Ab.: Monoclonal antibodies are those that are produced by the identical immune cells that are descended from the same parent cell. They produce anitibodies that bind to only one epitope or site on an antigen. This means that they are monospecific. This makes them useful in things like research because they can isolate a strain purely and completely. ...Read more

Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


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What are antibodies? 

What are antibodies? 

Part of immune syste: Antibodies are proteins made by your immune system to attach to things that the immune system is trying to eliminate from your body, such as bacteria and viruses. Normally they are made only against foreign substances (i.e. Those not naturally occurring in the body). Certain drugs, like Avastin (bevacizumab) for example, are also made as antibodies. ...Read more

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What exactly is an anti-streptococcal antibody titer?

What exactly is an anti-streptococcal antibody titer?

IgM or IgG anti stre: In general antibody titers are (blood or saliva or wherever the sample is )tests that measure the immunoglobulines associated to certain diseases (in this case streptococal)that indicate whether or not the body has developed defenses against. Igm elevated means a "recent" infection, IgG elevation means old or previous exposure. ...Read more

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Elevated EBV ab VCA IgG <8 and EBV nucleaer antigen ab IgG test 4.2. & anti-dna(ss)igg ab qn ( 119)& c react protien(5.6) what are implications?

Elevated EBV ab VCA IgG <8 and EBV nucleaer antigen  ab IgG test 4.2. & anti-dna(ss)igg ab qn ( 119)& c react protien(5.6)  what are implications?

Nothing.: Ebv antibodies indicate you had a previous infection, but not active. The c-reactive protein needs a units indicator - that is either normal or somewhat elevated. The anti ss dna is extremely nonspecific and very rarely indicated; I have no idea why that was ordered, discuss with your doctor. ...Read more

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Reactivated EBV 9 months after first infection. Could i be immunodeficient? Antibody count: 65 ab VCA igm; 53 ea ab igg; 431 ab VCA igg; 289 ebna igg.

Reactivated EBV 9 months after first infection. Could i be immunodeficient? Antibody count: 65 ab VCA igm; 53 ea ab igg; 431 ab VCA igg; 289 ebna igg.

No: Unfortunately ebv stays alive forever in one's lymphocytes and can get activated easily in susceptible people without known immunodeficiency. However you may call that an immunodeficiency given that all people have been infected with it yet only few would have recurrent ebv problem. ...Read more

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Is antithyroglobulin antibody test the same as thyroglobulin antibody test?

Is antithyroglobulin antibody test the same as thyroglobulin antibody test?

Yes: Both address presence of antibody to the rhyroglobulin molecule made by thyroid gland. See this site for more info. http://www.nlm.nih.gov/medlineplus/ency/article/003557.htm. ...Read more

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My serum test is negative for endomysial antibody iga, ttg tissue transglutasminase iga, gliadin antibody igg. But positive for gliadin antibody iga?

My serum test is negative for endomysial antibody  iga, ttg tissue transglutasminase iga, gliadin antibody igg. But positive for gliadin  antibody iga?

Treat the person: Lab tests mean nothing in isolation, and have many false positives and false negatives. The decision to make a trial of a gluten-free diet will be between you and your gastroenterologist or dermatologist based on the big picture. ...Read more

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Describe polyclonal and monoclonal antibody production?

Cells vs, animals: A monoclonal antibody is produced by in-vitro manipulation by expoanding a single cell making a desired antibody. Polyclonal antibodies are usually derived from immunizing an animal and colletcting its blood/serum containing the antibody. Polyclonal antibodies are a mixture of a large number of different cells. ...Read more

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What happens if "h. pylori IgG antibodies serum by ELISA positive"?

What happens if "h. pylori IgG antibodies serum by ELISA positive"?

H. pylori infection: .. which causes gastritis with symptoms of early satiety, abdominal pain, heartburn. If you are symptomatic, then you will need the treatment. If you are not symptomatic or have responded to treatment already, then your test result indicates ongoing antibody production (normal immune response to previous infection) and no treatment is required. Good luck! ...Read more

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Is a core positive antibody for hepetitis b is dangerous. Igm antibody negetive. Surface antigen negetive with surface antibody positive. Explain?

Is a core positive antibody for hepetitis b is dangerous. Igm antibody negetive. Surface antigen negetive with surface antibody positive. Explain?

Past infection: The results you described are consistent with a past infection with hepatitis b from which you have recovered. You body made antibodies to the constituents of the virus. These results are not a cause for concern. ...Read more

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HBV test results: Hepatitis B Surface Antigen: Nonreactive; Hepatitis B Core Antibodies: Reactive; HBV PCR: Negative. Need any medication or vaccine?

HBV test results: Hepatitis B Surface Antigen: Nonreactive; Hepatitis B Core Antibodies: Reactive; HBV PCR: Negative.  Need any medication or vaccine?

Excellent question: and your story stumps many a doctor, often! :) a lot of the recommendations depend on - are you someone with risk factors for HBV? is this the first time that it has been checked? are your liver enzymes normal? are you about to undergo any procedures/ treatments that could put you at risk for HBV? If you have no sig risk factors, yes, I'd vaccinate you if there's potential for exposure. ...Read more

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Does anyone have information on or personal experiences with antiphospholipid antibody syndrome?

Miscarriage: Apa, along with lupus anti-coagulant antibody, are two antibodies that attack the areas in the cell wall of growing tissue, especially the fast-growing placental tissue of an early pregnancy. These are newly-discovered causes for recurrent miscarriage, but also place the patient at higher risk for developing a blood clot, especially with hormone use, later in life. ...Read more

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What is the purpose of monoclonal antibodies?

What is the purpose of monoclonal antibodies?

Diagnosis and Rx: Monoclonal antibodies are used in many diagnostic tests. These are also used in the treatment of some tumors. However, monoclonal immunoglobulins in a person are markers of disease, especially multiple myeloma. ...Read more

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Cardiolipin antibodies IgM and urine protein 72mg/l ? Ana negative.

Cardiolipin antibodies IgM and urine protein 72mg/l ? Ana negative.

See details: The urine protein is within normal limits. How strongly positive is the igm cardiolipin. Only high levels of positivity have any clinical significance. Why were the tests ordered in the first place? ...Read more

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Ebv panel. Ebv nuc antigen igg=157, early ag igg=12.7, EBV VCA igg=112, EBV VCA igm=10.6. Please explain. Concerned about spleen. Symp=fatigue/fog?

Ebv panel. Ebv nuc antigen  igg=157, early ag igg=12.7, EBV VCA igg=112, EBV VCA igm=10.6.  Please explain.  Concerned about spleen. Symp=fatigue/fog?

? Active infection: It's impossible for me to answer with certainty since i don't know the normal ranges your lab uses. If early ag & vca igm are elevated above normal this indicates active ebv infection.I don't know if it is acute or chronic without knowing your history. If chronic i see that as a sign of poor immune function.Immune-boosting herbs/supplements & IV vit c drips may help, but find why immunity is poor. ...Read more

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How do antibodies work in the immune system?

How do antibodies work in the immune system?

Complicated: Antibodies basically surround infectious organisms (usually bacteria) and help either neutralize them or lead to their destruction. ...Read more

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Hiv ab,1/2, eia with relx result repeatedly reactive. HIV 1/2ab differentiation w/refl hiv1 antibody negative hiv2 antibody negative. pos or neg hiv?

Hiv ab,1/2, eia with relx result repeatedly reactive. HIV 1/2ab differentiation w/refl hiv1 antibody negative hiv2 antibody negative. pos or neg hiv?

It depends: In a situation like this you have one positive test and one negative test. The lab should run a tie-breaker test (HIV RNA) to give you a real answer. Also, the first test may be an older test 2nd or 3rd generation) instead of the latest 4th generation) test. It also depends on if you have flu-Like symptoms. Seek help from a specialist in HIV who can help you understand. ...Read more

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Husband works in health field had testing came back as having antibodies to herpes 1 what does that mean or me he has no signs of anything ?

Husband works in health field had testing came back as having antibodies to herpes 1 what does that mean or me he has no signs of anything ?

Past exposure: The vast majority of adults have IgG antibodies to Herpes 1. The odds are strong that you do as well. This just means that years ago, probably in childhood, he (like almost everyone) was exposed to that virus. He may (or may not) have gotten a cold sore. Most people with healthy immune systems keep it in in check & never get cold sores, but some do when under stress. If no symptoms not contagious. ...Read more

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