Doctor insights on:
Decrease pressure: Mannitol is used to manipulate osmotic (or oncotic) forces to shift water from the tissue into the blood vessels. In the kidney, mannitol increases water excretion. So, in patients with increased intracranial pressure, the intent is to decrease the pressure by using mannitol to "pull" fluid out of the brain and then excrete it via the kidneys. ...Read more
No: Some will accelerate the GI tract motility causing diarrhea, but most sugar-alcohols are great diabetic substitute sweetener. They are less sweet than sugar, and artificial sweeteners are much sweeter. They do stimulate insulin, but less than glucose. Aspartmae is an artifical sweetener. ...Read more
Yes: Unfortunately erythritol, isomalt, sorbitol, and mannitol are recognized as a sugar source by the bacteria in our mouths and can cause cavities. Xylitol is the only sweetener that cannot be digested by oral bacteria. Chewed in small amounts (one or two pieces a day) xylitol can remineralize teeth. Gum with recaldent can also remineraize your teeth. ...Read more
Diuretic: Manitol is a sugar like substance which is filtered by the kidney and not reabsorved like glucose would so it remains in the kidney tubules and it acts as a urine volume enhancer by pulling water and electrolytes into the urine space and ultimately out in the urine so as to be an osmotic diuretic. It is used mainly to reduce brain edema acutely. ...Read more
Need special tests: This is a rather sophisticated question. One that I can only answer in a very simplistic way. Basically, mannitol, sorbitol, adonitol, and arabinose are sugar alcohols. Not all bacteria can process these reduced sugars. The only way to tell is to have special media, each containing only one sugar alcohol with an indicator. Hen the media would be inoculated individually with the bacterium. ...Read more
Can streptococcus epidermis be + or - in msa or mannitol fermentation result? Any answers appreciated!
Should be: There is somewhat limited literature, but it seems to be a reasonable test. However, "very accurate" is subjective; it appears to have about 90% sensitivity, only about 50% specificity though. ...Read more
Frnd is suffering from cerebral edema for last one month but doctors never used mannitol...Can it be cure with oral tablets only?
Doctors are not using mannitol to cure cerebral edema. Are there other ways too? My friend is semiconscious for last one month. Plz suggest
How long can cerebral edema take to be cured. Doctors aren't giving mannitol. But there is improvement in friends health. 60% conscious now.
Each case different: It depends how severe is the brain edema and what the cause is. Mannitol is temporary treatment and only a protective measure. It usually resolves after a few days while the medical team tries to minimize damage with the different treatment modalities. Being conscious is the best sign of improvement. ...Read more
Loose stool, etc: All artificial sweeteners do not cause cavities but the liquid or food that you consume may contain other compounds that could be bad for your teeth, such as acid. Some research also indicates that if you consume large quantities of any artificial sweetener it may be hazardous to your health. Another side effect is if you consume large quantities of an artifcial sweetener, you can get diarrhea. ...Read more
Dysnea + cough, negative mannitol test, high nitric oxide, normal FCV & FEV1, very low MEF 25, low DLCO, high PEmax & very low PImax. What disease?
See pulmonologist: If the corrected DLCO is low, I would suspect interstitial lng disease. However it is difficult to make a diagnosis based on test results alone and I would thus recommend that you consult a pulmonologist. If your FeNO is only slightly elevated (35 ppb range), it may mean nothing. But if highly elevated, then an eosinophilic inflammation should be considered. ...Read more
Can mannitol be used to reduce edema weeks after surgery, or only immediately after trauma? Patient suffers from aphasia after removal of glioblastoma
Because of negative mannitol test & heavy dysnea, Dr. Ordered methacholine challenge, but my dna shows pseudocholinesterase deficiency. Safe test?
Did you have PFTs? First do that, Rrare to use methacholine in the US as those with asthma can have a severe response. Discuss your deficiency and PFTs wtth your doctor. Methacholine is metabolized by acethycholinesterase and si resistent to inactivation by pseuodcholinesterase, so that should not be a factor.
See http://www. Rxlist. Com/provocholine-drug/clinical-pharmacology. Htm ...Read more
sorbitol, mannitol or xylitol and even splenda upset my stomach. Is there a chewable calcium citrate without artificial sweet? I've had roux en y.
Exhaled nitric oxide elevated, mannitol test negative. Nothing to see in CT. Severe dyspnea with normal lung function and cough. Any suggestion?
Other causes: Exhaled nitric oxide need to be over 35 ppb to be considered abnormal. Severe dyspnea may be from a cardiac issue and if the problem occurs with breathing air in, it may be from vocal cord dysfunction. An ENT doctor may be able to confirm the diagnosis. Let me know what turns out eventually ...Read more