Doctor insights on:
Renova Cancer Agent
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
New Treatments: Here are 3 recent medications used to fight metastatic prostate cancer. 1. Jevtana (cabazitaxel) - intravenous chemotherapy 2. Zytiga (abiraterone acetate) (abiraterone) - oral androgen biosynthesis inhibitor 3. Provenge (sipuleucel-t) - immunotherapy. ...Read moreSee 2 more doctor answers
Clinicaltrials.gov: Clinicaltrials.Gov is a comprehensive database of clinical trials in the United States and around the world. You may also find www.Researchmatch.Org useful, as it is geared specifically to patients. (note: researchmatch is an nih-funded project i learned about at vumc through the work of paul harris - I have no conflict of interest). ...Read more
Trade name: Trade name drugs are sold under a monopoly so the drug companies can recoup their investment in researching and developing a drug. Generic drugs are sold by competing companies once the original patent expires. The competition drives down prices and limits profits. ...Read moreSee 1 more doctor answer
Years: That is billion dollar question and also equally that expensive to release the drug . Safety and effectiveness is tested in phase iii for fda approval to go for phase IV to public rx may take may take long time, some times years and some times never drug disappears . Public safety is essential, look what happened to thalidamide , a tragedy. ...Read more
My dr. wants to try me on the cancer drug tamoxifen for infertility. I have never had cancer. Is this healthy?
Benefit/risk: Tamoxifen is a SEAM (selective estrogen receptor modulator). It inhibits estrogen receptor pathway in breast, but stimulates it in ovary and uterus. It may increase fertility for a time, but reduce later due to constant stimulating. Its stimulating effect can also increase risk of uterine cancer. Other side effects from tamoxifen include thrombosis, stroke, etc, esp at long-term use. ...Read moreSee 1 more doctor answer
What do you suggest if my dr. wants to try me on the cancer drug tamoxifen for infertility. I have never had cancer. is this ok?
Yes: Tamoxifen is used to prevent breast cancer where it suppresses estrogen binding, it can act as an estrogenic stimulus on ovarian tissue initiating ovulation induction by a mechanism similar to clomiphene citrate. This drug Clomid is able to bind to estrogen receptors in the hypothalamus. preventing the brain from seeing the negative signal from estrogen This stimulates production of FSH. ...Read more
Multidisciplinary: Developing a cancer drug is an involved process that need contributions of chemists, biochemists, molecular biologists, doctors, pharmacologists, and more. Nanotechnology has not played a major role, yet. ...Read more