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Doctor insights on: Renal Failure Lead To Metabolic Acidosis

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Can haemodialysis correct metabolic acidosis in renal failure patient?

Can haemodialysis correct metabolic acidosis in renal failure patient?

Renal Replacement Th: Dialysis is one of the treatments for metabolic acidosis. Depending on the cause as well as the other medical problems and type of the acidosis, correcting the inciting problem is the first step dialysis may or may not be needed. ...Read more

Dr. Fred McCurdy
62 doctors shared insights

Metabolic Acidosis (Definition)

Metabolic acidosis occurs either from primary acid retention, renal (kidney) dysfunction/failure or bicarbonate (sodium bicarbonate) losses. Primary acid retentions cause anion-gap metabolic acidosis from these etiologies (methanol, uremia, diabetic ketoacidosis, para-aldehyde, isoniazid, lactic acidosis, ethylene glycol, salicylates). Kidney's dysfunction leads to acidosis. Finally any loss ...Read more


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Can dehydration lead to metabolic acidosis?

Can dehydration lead to metabolic acidosis?

It usually does: The contraction of the fluid volume caused by dehydration routinely leads to a metabolic acidosis as the metabolism begins to shift to more fat breakdown & those byproducts add to the acidity of the blood.Fluid expansion through oral or IV re-hydration can correct this quickly by exposing the blood to buffer compounds in the tissues. ...Read more

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What is metabolic acidosis in chronic renal failure from?

What is metabolic acidosis in chronic renal failure from?

Unable to remove: Metabolic acidosis is a constituent of renal failure, arising mainly from the inability of kidney to remove excess acids in blood. ...Read more

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Hi, is the metabolic acidosis in chronic renal failure fatal ?

Hi, is the metabolic acidosis in chronic renal failure fatal ?

Acidosis: The simple answer is yes. However, the amount of acid has to be very high for that to happen. High amounts of acid in the blood interfere with many, if not all, biologic processes in the human body such as the effect of Insulin lowering blood sugar, the normal metabolism of proteins and fats that are essential for life, and even normal heart beat, just to name a few. ...Read more

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Why can hypovolemic shock lead to renal failure?

Why can hypovolemic shock lead to renal failure?

Shock: Hypovelemic shock can cause renal failure from either the body conserving free water due to severe dehydration and producing a low volume of highly concentrated urine or from a lack of blood flow and oxygen to the kidneys producing intrinsic kidney injury and renal failure. ...Read more

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Can heart failure cause renal failure?

Can heart failure cause renal failure?

Yes: Heart failure can cause decreased blood flow to the kidneys, causing decreased renal function. Renal failure can also exacerbate heart failure by increasing blood pressure and decreasing salt elimation, resulting in intravascular volume overload, resulting in increased pressure in the chambers of the left side of the heart. ...Read more

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Could liver failure lead to ards?

Could liver failure lead to ards?

Possibly: Liver failure may cause ARDS but many other things must be known to determine if this is the case or not. Fluid overload can present like ARDS but is not ards. ...Read more

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Does renal cell carcinoma lead to chronic renal failure?

Does renal cell carcinoma lead to chronic renal failure?

Not necessarily: Only if both the kidneys have to be removed if cancer on both sides. If only one kidney or a part of kidney only is removed and the remaining kidney is healthy dialysis is not required. ...Read more

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How can diabetic ketoacidosis (w/ metabolic acidosis) causes respiratory failure?

Due to acidosis.,,: The metabolic acidosis causes a respiratory compensation in an attempt by the body to keep the blood ph normal. The respiratory compensation is to increase minute ventilation (both respiratory rate and volume per breath!). So, the person with severe metabolic acidosis will be breathing fast and deeply. Doing this for an extended period of time can lead to fatigue resulting in respiratory failure. ...Read more

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Why does chronic glomerulonephritis lead to renal failure?

Complex: Chronic immune mediated inflammation of the glomeruli (filtering units), does them in over time and causes loss of ability to clear the daily toxin and water load. ...Read more

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Would renal failure result in hypo- or hyperkalemia? Why?

Would renal failure result in hypo- or hyperkalemia? Why?

Depends: Many factors contribute to serum potassium levels including residual kidney function, diuretic use, potassium intake, GI potassium loss (i.e. diarrhea), and acid/base status. It is possible to see high or low serum potassium levels in patients with renal failure but hyperkalemia (high potassium) is more commonly observed in patients with advanced renal dysfunction. ...Read more

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Can dehydration cause kidney failure?

Can dehydration cause kidney failure?

Absolutely!!!: Always stay well hydrated, especially during warm summer months... ...Read more

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How does the renal system compensates for metabolic acidosis and alkalosis?

How does the renal system compensates for metabolic acidosis and alkalosis?

Slowly & effectively: In response to acidosis, the kidney increases reabsorbtion of bicarbonate (sodium bicarbonate) from the tubular fluid, secretes more hydrogen ions, and generate more bicarbonate (sodium bicarbonate). Ammoniagenesis leads to increased formation of the buffering compounds. In responses to alkalosis, the kidney excretes more bicarbonate (sodium bicarbonate), decreases hydrogen ion secretion, and lowers rates of glutamine metabolism and ammonium excretion. ...Read more

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Does insulin resistance lead to kidney disease?

Does insulin resistance lead to kidney disease?

Not really: It is not Insulin resistance that causes kidney disease but instead poorly controlled diabetes. The most common causes of kidney failure in the us are diabetes, high blood pressure, and age. Many patients with Insulin resistance have difficult to control diabetes and thus are more likely to be poorly controlled and therefore more likely to develop kidney disease. ...Read more

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How frequently does rhabdomyolysis lead to kidney failure?

How frequently does rhabdomyolysis lead to kidney failure?

Variable: Depends on the degree of muscle injury/breakdown and whether the patient was adequately hydrated and acidosis was adequately treated in the acute episode. Mannitol is used as a diuretic to maintain maximal urinary flow to avoid injury to the kidney as well. ...Read more

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How can heart failure lead to chronic lung disease?

How can heart failure lead to chronic lung disease?

Yes: poorly optimized HF therapy, or long standing valvular heart disease can lead to pulmonary hypertension and damage to the lung blood vessels. ...Read more

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How can heart failure lead to cachexia?

How can heart failure lead to cachexia?

Hormonal: Severe and chronic heart failure can set into motion alterations of chemicals in the blood similar to other severe illnesses. Additional changes in appetite and psychological changes can affect diet as well as physical deconditioning. All of these factors can cumulatively lead to muscle wasting syndromes. Mild heart failure is usually not associated with these severe physiologic manifestations. ...Read more

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Can renal failiure leed to lung disesse?

Can renal failiure leed to lung disesse?

Yes: Acute renal failure can lead to increased volume ( salt& water) in the body . This can cause respiratory failure due to pulmonary edema( lungs become soggy, difficult to expand) . Treatment involves close observation, fluid management and in some cases dialysis. Sometimes kidney and lung can become involved by a disease process of blood vessels ( blood in the urine&sputum)- goodpasture' syndrom. ...Read more

Acidosis (Definition)

Normally our body chemistry is kept in a narrow range, and in particular the amount of acid in the body is kept within a narrow range. The amount of acid is measured by a value called the ph. It is normally a value between 7.35 and 7.45, values below 7.35 are considered to be "acidotic" a patient with this value of the blood chemistry ...Read more


Dr. Tarek Naguib
600 doctors shared insights

Kidney Failure (Definition)

A condition in which your kidneys suddenly stop working normally. Since your kidneys remove waste products and help balance water and salt and other minerals (electrolytes) in your blood, when your kidneys stop working, waste products, fluids, and electrolytes build up in your body. This can cause problems ...Read more