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Doctor insights on: Renal Failure Lead To Metabolic Acidosis

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What is metabolic acidosis in chronic renal failure from?

What is metabolic acidosis in chronic renal failure from?

Unable to remove: Metabolic acidosis is a constituent of renal failure, arising mainly from the inability of kidney to remove excess acids in blood. ...Read more

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Dr. Fred McCurdy
60 doctors shared insights

Metabolic Acidosis (Definition)

Metabolic acidosis occurs either from primary acid retention, renal (kidney) dysfunction/failure or bicarbonate (sodium bicarbonate) losses. Primary acid retentions cause anion-gap metabolic acidosis from these etiologies (methanol, uremia, diabetic ketoacidosis, para-aldehyde, isoniazid, lactic acidosis, ethylene glycol, salicylates). Kidney's dysfunction leads to acidosis. Finally any loss ...Read more


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Can haemodialysis correct metabolic acidosis in renal failure patient?

Can haemodialysis correct metabolic acidosis in renal failure patient?

Renal Replacement Th: Dialysis is one of the treatments for metabolic acidosis. Depending on the cause as well as the other medical problems and type of the acidosis, correcting the inciting problem is the first step dialysis may or may not be needed. ...Read more

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Hi, is the metabolic acidosis in chronic renal failure fatal ?

Hi, is the metabolic acidosis in chronic renal failure fatal ?

Acidosis: The simple answer is yes. However, the amount of acid has to be very high for that to happen. High amounts of acid in the blood interfere with many, if not all, biologic processes in the human body such as the effect of Insulin lowering blood sugar, the normal metabolism of proteins and fats that are essential for life, and even normal heart beat, just to name a few. ...Read more

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How does the renal system compensates for metabolic acidosis and alkalosis?

How does the renal system compensates for metabolic acidosis and alkalosis?

Slowly & effectively: In response to acidosis, the kidney increases reabsorbtion of bicarbonate (sodium bicarbonate) from the tubular fluid, secretes more hydrogen ions, and generate more bicarbonate (sodium bicarbonate). Ammoniagenesis leads to increased formation of the buffering compounds. In responses to alkalosis, the kidney excretes more bicarbonate (sodium bicarbonate), decreases hydrogen ion secretion, and lowers rates of glutamine metabolism and ammonium excretion. ...Read more

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Can you tell me how the renal system compensates for metabolic acidosis and alkalosis?

Can you tell me how the renal system compensates for metabolic acidosis and alkalosis?

Metabolic issues: The kidneys are very smart at keeping the body at the ph level. The kidneys are capable of getting rid of large amounts of acids (hydrogen ions) and reabsorbing bicarbonate (sodium bicarbonate) to keep the body in homeostasis. We excrete acid (h+) through titratable acidity and ammonium. ...Read more

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Diagnosed & hospitalized Apr-2 through Apr. 6 w/pyelonephritis, common bile duct dilation, dehydration, metabolic acidosis, renal cyst. Still in pain!

Diagnosed & hospitalized Apr-2 through Apr. 6 w/pyelonephritis, common bile duct dilation, dehydration, metabolic acidosis, renal cyst. Still in pain!

And pain: 55F DC from Hosp after pyelonephritis, bile duct dilation etc. notes still in pain. Sorry about the pain you are having. You were very ill I suspect. But do you have a question? Your health care team there knows more about you than you can tell us. Therefore recommend if you have a question.you ask them. ...Read more

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Can dehydration lead to metabolic acidosis?

It usually does: The contraction of the fluid volume caused by dehydration routinely leads to a metabolic acidosis as the metabolism begins to shift to more fat breakdown & those byproducts add to the acidity of the blood.Fluid expansion through oral or IV re-hydration can correct this quickly by exposing the blood to buffer compounds in the tissues. ...Read more

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How can diabetic ketoacidosis (w/ metabolic acidosis) causes respiratory failure?

Due to acidosis.,,: The metabolic acidosis causes a respiratory compensation in an attempt by the body to keep the blood ph normal. The respiratory compensation is to increase minute ventilation (both respiratory rate and volume per breath!). So, the person with severe metabolic acidosis will be breathing fast and deeply. Doing this for an extended period of time can lead to fatigue resulting in respiratory failure. ...Read more

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How does metabolic acidosis affect liver clearance of drugs? I.E. Should i stop my medications during metabolic acidosis

How does metabolic acidosis affect liver clearance of drugs? I.E. Should i stop my medications during metabolic acidosis

See below.: Patients with acidosis severe enough to affect drug metabolism are usually in the ICU with bigger problems. Mild degrees of acidosis are probably not sufficient to affect the clearance of many medications. ...Read more

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How can metabolic acidosis cause kussmaul breathing?

How can metabolic acidosis cause kussmaul breathing?

Yes.: Kussmaul breathing is a deep and labored breathing pattern often associated with severe metabolic acidosis, particularly diabetic ketoacidosis (DKA) but also renal failure. It is a form of hyperventilation, which is any breathing pattern that reduces carbon dioxide in the blood due to increased rate or depth of respiration. In metabolic acidosis, breathing is first rapid and shallow. ...Read more

Acidosis (Definition)

Normally our body chemistry is kept in a narrow range, and in particular the amount of acid in the body is kept within a narrow range. The amount of acid is measured by a value called the ph. It is normally a value between 7.35 and 7.45, values below 7.35 are considered to be "acidotic" a patient with this value of the blood chemistry ...Read more


Dr. Tarek Naguib
587 doctors shared insights

Kidney Failure (Definition)

The kidneys do several tasks. Dialysis is necessary when one or more of the following occur, that can't be remedied or palliated with medications: 1. Insufficient clearance of daily toxins in food and metabolic waste 2. Insufficient clearance of excess water 3. Dangerous electrolyte imbalance, ...Read more