Doctor insights on:
Renal Cell Carcinoma Metastatic Sites
My brother has been diagnosed with metastatic renal cell carcinoma stage 4. Am i at risk of this disease . Is this cancer rare?
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
My brother has metastatic renal cell carcinoma and it's spread the doctor said he could pass anytime y r they still giving him chemotherapy?
So sorry : Once cancer metastasizes, it is no longer curable. However, individuals can live for some time especially if they are being treated by chemo or targeted therapies. I don't know your brother's exact situation nor dx. If treatment is too toxic for him, he can elect to stop. Drs may be giving him palliative tx which can help with pain and other symptoms. When time comes, consider hospice to help all. ...Read more
I had nephrectomy in feb. After that i was diagnosed as metastatic renal cell carcinoma (lung cancer). But i don't have any symptoms as doc said.Why?
Congratulations: Renal cell carcinoma is notoriously capricious and unpredictable. It's common for a lung metastasis to vanish or stay stable for many years, especially after removal fo the primary tumor. I'm going to assume the diagnosis is accurate. Cherish being alive and be thankful for whatever time you have left -- fill it with love and good things. ...Read more
Get a good md: Find a doctor you can trust. Get a second opinion if you feel the need to either confirm the treatment course or find a different path. Consider removal of tumor in kidney if possible. Treat sites of metastatic disease aggressively if possible. ...Read more
Treat or observe: Renal carcinoma is a primarily surgical disease. Most patients likely benefit from excision of tumors with the option of partial kidney removal allowing preservation of renal function compared to total removal. Newer options for small tumors include thermal ablation where cold or heat destroys the tumor. In some patients with small tumors and poor health or old age, surveillance can be pursued. ...Read moreSee 1 more doctor answer
Varies with stage: Fortunately many renal cell carcinomas are now being diagnosed at an early stage (when the tumor is small and doesn't invade any other structures) thanks to improvements in imaging (ct scan etc). If early stage, many patients do very well after the tumor is removed. However, as the stage of the tumor increases, the risk of the cancer behaving aggressively increases. So stage helps to predict. ...Read more
Unusual but possible: Metastasis (spread) to the skin is uncommon for renal cell carcinoma. Lung is a much moe common site of spread. However, skin metastasis has been described. In fact, there are patients who were originally diagnosed solely through the biopsy of a suspicious skin lesion. Fortunately, unusual skin lesions are often accessible for biopsy which should decrease the uncertainty of diagnosis. ...Read moreSee 1 more doctor answer
Poor: Unfortunately even with chemo, stage IV renal cell has a short survival time. Some reasonably good chemo agents are coming available but present therapies may work for a while, then quit working. ...Read more
Varies: Even within stage 4, there are varying severities of disease. Survival can occasionally go beyond five years though most people will succumb in two or less years. ...Read more
?egfr??: Please avoid using abbreviations...they may have different meaning to different folks. Is this epidermal growth factor receptor(EGFR) that you are talking about? or is this something related to GFR(glomerular filtration rate) which is a test for Kidney function???. Please clarify so that we can address your question properly. ...Read more
It depends: I know that's what we always say. But stage 4 renal cancer prognosis depends on many factors. Someone who is very ill with an elevated ldh, elevated calcium, and anemia has months to a year. Someone who responded to immunotherapy and has normal labs may have several years or more. Your doctor knows, and if he/she is not saying, ask. And say you want the truth. ...Read moreSee 2 more doctor answers
Please: Consult your urologist or the md who diagnosed the disease. Blindly my advise would be if you have a medical school in your proximity, even if many miles away, i would make an appointment with them immediately. Do not neglect the problem every day should count! ...Read more
Is polycythemia the cause of renal cell carcinoma or renalcell carcinoma the cause of polycythemia?
Polycythemia: Polycythemia is not the cause of renal cell carcinoma. ...Read more
Most likely Stage I: All tumors are staged by the tumor, nodes, metastasis (staging system). Stage i kidney tumors are less than 7 CM in size and have no evidence of lymph node as well as distant metastasis. Stage ii tumors are larger than 7 CM and have no lymph node or distant metastasis. Stage iii tumors are locally advanced. Stage IV tumors have spread to lymph nodes or other organs. ...Read moreSee 4 more doctor answers
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