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Doctor insights on: Renal Cell Carcinoma Metastatic Sites

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Dr. Barry Rosen
4,298 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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How will be RBC count, pcv, hb in metastatic renal cell carcinoma?

How will be RBC count, pcv, hb in metastatic renal cell carcinoma?

Unpredictable: Most patients will have a drop in red count due to the cancer itself. Some will be normal, but a small percentage of renal cancers produce excess epo and will have a high rbc. ...Read more

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My brother has metastatic renal cell carcinoma and it's spread the doctor said he could pass anytime y r they still giving him chemotherapy?

My brother has metastatic renal cell carcinoma  and it's spread the doctor said he could pass anytime y r they still giving him chemotherapy?

So sorry : Once cancer metastasizes, it is no longer curable. However, individuals can live for some time especially if they are being treated by chemo or targeted therapies. I don't know your brother's exact situation nor dx. If treatment is too toxic for him, he can elect to stop. Drs may be giving him palliative tx which can help with pain and other symptoms. When time comes, consider hospice to help all. ...Read more

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I had nephrectomy in feb. After that i was diagnosed as metastatic renal cell carcinoma (lung cancer). But i don't have any symptoms as doc said.Why?

I had nephrectomy in feb. After that i was diagnosed as metastatic renal cell carcinoma (lung cancer). But i don't have any symptoms as doc said.Why?

Congratulations: Renal cell carcinoma is notoriously capricious and unpredictable. It's common for a lung metastasis to vanish or stay stable for many years, especially after removal fo the primary tumor. I'm going to assume the diagnosis is accurate. Cherish being alive and be thankful for whatever time you have left -- fill it with love and good things. ...Read more

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Any advice for renal cell carcinoma?

Any advice for renal cell carcinoma?

Get a good md: Find a doctor you can trust. Get a second opinion if you feel the need to either confirm the treatment course or find a different path. Consider removal of tumor in kidney if possible. Treat sites of metastatic disease aggressively if possible. ...Read more

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What is done for renal cell carcinoma?

What is done for renal cell carcinoma?

Treat or observe: Renal carcinoma is a primarily surgical disease. Most patients likely benefit from excision of tumors with the option of partial kidney removal allowing preservation of renal function compared to total removal. Newer options for small tumors include thermal ablation where cold or heat destroys the tumor. In some patients with small tumors and poor health or old age, surveillance can be pursued. ...Read more

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How deadly is renal cell carcinoma?

How deadly is renal cell carcinoma?

Varies with stage: Fortunately many renal cell carcinomas are now being diagnosed at an early stage (when the tumor is small and doesn't invade any other structures) thanks to improvements in imaging (ct scan etc). If early stage, many patients do very well after the tumor is removed. However, as the stage of the tumor increases, the risk of the cancer behaving aggressively increases. So stage helps to predict. ...Read more

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Is there cure for renal cell carcinoma?

Is there cure for renal cell carcinoma?

Yes: If it is removable with surgery cure is very likely. Most patients do well with this cancer. ...Read more

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Can renal cell carcinoma spread to somebody's skin?

Can renal cell carcinoma spread to somebody's skin?

Unusual but possible: Metastasis (spread) to the skin is uncommon for renal cell carcinoma. Lung is a much moe common site of spread. However, skin metastasis has been described. In fact, there are patients who were originally diagnosed solely through the biopsy of a suspicious skin lesion. Fortunately, unusual skin lesions are often accessible for biopsy which should decrease the uncertainty of diagnosis. ...Read more

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Can renal cell carcinoma eventually spread to the skin?

Can renal cell carcinoma eventually spread to the skin?

Yes: Usually expands locally, then in veins, then lung is common.But when metastasis occurs it can end up secondarily anywhere. ...Read more

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What is the prognosis for stage 4 renal cell carcinoma?

What is the prognosis for stage 4 renal cell carcinoma?

Poor: Unfortunately even with chemo, stage IV renal cell has a short survival time. Some reasonably good chemo agents are coming available but present therapies may work for a while, then quit working. ...Read more

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What is papillary renal cell carcinoma? Can it be treated?

What is papillary renal cell carcinoma? Can it be treated?

Yes: Papillary renal cell carcinoma is a type of kidney cancer. Surgery is the best option, if feasible. ...Read more

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How long would someone with stage 4 renal cell carcinoma have?

How long would someone with stage 4 renal cell carcinoma have?

Varies: Even within stage 4, there are varying severities of disease. Survival can occasionally go beyond five years though most people will succumb in two or less years. ...Read more

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Diagnosed with renal cell carcinoma last week said I was stage 1?

Diagnosed with renal cell carcinoma last week said I was stage 1?

Good prognosis: Stage 1: the cancer is only within the kidney, and has not spread. This stage has the best long-term survival and is most likely to be cured with surgery. The five year survival rate is almost 90%. ...Read more

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Is it possible to have renal cell carcinoma and have a normal egfr?

Is it possible to have renal cell carcinoma and have a normal egfr?

?egfr??: Please avoid using abbreviations...they may have different meaning to different folks. Is this epidermal growth factor receptor(EGFR) that you are talking about? or is this something related to GFR(glomerular filtration rate) which is a test for Kidney function???. Please clarify so that we can address your question properly. ...Read more

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How long does someone with stage 4 renal cell carcinoma have? Weeks? Months? A year?

How long does someone with stage 4 renal cell carcinoma have?  Weeks?  Months?  A year?

It depends: I know that's what we always say. But stage 4 renal cancer prognosis depends on many factors. Someone who is very ill with an elevated ldh, elevated calcium, and anemia has months to a year. Someone who responded to immunotherapy and has normal labs may have several years or more. Your doctor knows, and if he/she is not saying, ask. And say you want the truth. ...Read more

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What exactly does grade 1, 2, 3, 4 of the tumor mean in clear cell renal cell carcinoma?

What exactly does grade 1, 2, 3, 4 of the tumor mean in clear cell renal cell carcinoma?

How cells look: Grading refers to how closely the cancer cells resemble normal kidney cells. Cells that are more abnormal (ie higher grade) are associated with a worse prognosis. ...Read more

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Could you please tell me where is the best medical center for treating renal cell carcinoma?

Could you please tell me where is the best medical center for treating renal cell carcinoma?

Please: Consult your urologist or the md who diagnosed the disease. Blindly my advise would be if you have a medical school in your proximity, even if many miles away, i would make an appointment with them immediately. Do not neglect the problem every day should count! ...Read more

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What stage is a 7 mm renal cell carcinoma?

What stage is a 7 mm renal cell carcinoma?

Most likely Stage I: All tumors are staged by the tumor, nodes, metastasis (staging system). Stage i kidney tumors are less than 7 CM in size and have no evidence of lymph node as well as distant metastasis. Stage ii tumors are larger than 7 CM and have no lymph node or distant metastasis. Stage iii tumors are locally advanced. Stage IV tumors have spread to lymph nodes or other organs. ...Read more

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Dr. Terence Chapman
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