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Doctor insights on: Remicade Resistance Ulcerative Colitis

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Tolerance (Definition)

When one takes a drug, such as heroin or alcohol, repeatedly, 'tolerance' develops because more of the drug is needed to give the same effect on the body/brain; e.g. Liver enzymes r stimulated to metabolize the drug faster and faster. There may be a strong genetic predisposition to addiction, some studies suggesting that 1 of 10 people will become dependent on alcohol or some ...Read more


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When do I decide that it is time for remicade (infliximab) for ulcerative colitis?

When do I decide that it is time for remicade (infliximab) for ulcerative colitis?

When it's bad enough: See your GI doc. Remicade (infliximab) recently ok'd for uc, as well as crohn's. Like steroids, can put people in remission quickly; unlike steroids can maintain it. If Mesalamine orally and rectally don't work, if immuno-suppressives like 6-meraptopurine or azathioprine don't work; if need to stay on steroids, or repeatedly go on steroids, or severe sx, consider remicade, (infliximab) cyclosporin, or even surgery. ...Read more

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I may be starting remicade (infliximab) treatment in few weeks for severe left sided ulcerative colitis. Can I use predinosone for temp relief?

Not on your own: Ulcerative colitis is a serious medical condition that need to be under constant medical supervision to achieve prolonged periods of remissions, and prevent complications like bleeding , colitis, perforations , systemic diseases and malignancy , if your physician prescribes predinosone (steroids) you should take. ...Read more

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Can the medications typically taken for ulcerative colitis (remicade, 6mp) effect male infertility?

Can the medications typically taken for ulcerative colitis (remicade, 6mp) effect male infertility?

Perhaps: Infliximab may decrease sperm motility and the number of normal oval forms. Whether these changes translate into impaired fertility is unknown. 6mp has been rarely associated with birth defects even when the father takes the medication. The benefits, however, often outweigh the risks and you need to discuss this with your doctor. ...Read more

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For 10 yrs I've been on 6mp for Ulcerative Colitis with ups and downs. How should I decide between 6mp, Entyvio, and Remicade/Humira moving forward?

For 10 yrs I've been on 6mp for Ulcerative Colitis with ups and downs. How should I decide between 6mp, Entyvio, and Remicade/Humira moving forward?

Ulcerative Colitis: By visiting a gastroenterology clinic that you feel takes excellent care of your UC, keeps you informed of any changes needed, makes you feel like you are important, and calls you back within 12-24 hours of a phone call to their office. Finding the right doctor(s) for your condition is essential. Excellent doctors can also provide excellent insight into which medication(s) would work best for you. ...Read more

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What tests (beside TB test) and vaccinations are needed before starting first time remicade (infliximab) fusion for left-sided ulcerative colitis? Mmr vaccine?

What tests (beside TB test) and vaccinations are needed before starting first time remicade (infliximab) fusion for left-sided ulcerative colitis? Mmr vaccine?

Check hepatitis B: The risk of reactivation of tuberculosis and hepatitis b when taking Remicade (infliximab) obligates pre-treatment testing. Live vaccines can not be accepted while on the drug. Your doctor will no doubt be candid when discussing all the risks of "biologic treatment"--please discuss these with him before initiating this very efficacious and generally well-tolerated drug class. ...Read more

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Is anyone suffering with ulcerative colitis and having infliximab treatment effect?

About 30% : Effective in about 30%. Effect may be short-lived or long term. Expensive, inconvenient therapy but may allow surgery in a healthier patient. A surgeon should always be part of the therapy team for a patient with uc who does not respond to the usual treat ment plan. ...Read more

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Is it safe for me to have botox facial injections whilst on infliximab, methotrexate and asacol (mesalamine) treatment for ulcerative colitis?

It is safe: Botox does not interact with these and almost all other medications. I have several patients with colitis on these drugs and have injected Botox for their chronic migraines without any side effects. ...Read more

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How to deal with ulcerative colitis?

How to deal with ulcerative colitis?

Medications: ? Re how treat Ulcerative Colitis, UC. See a Gastroenterologist who specializes in UC. If symptoms persist despite therapies, ask the doctor if he would approve of the use of Cannabis. Do not use if he disapproves, and see a Cannabis Medicinal Consultant if he does approve. I have treated UC patients who have reported benefit from Cannabis. ...Read more

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Can whipworms treat ulcerative colitis?

Can whipworms treat ulcerative colitis?

Ongoing research: There is a lot of promising data that looks at whip worms but also other living organisms like bacteria in making a difference in ulcerative colitis and crohn's disease. The data are still preliminary in my mind and are not ready for prime time, mostly because we do not fully understand the biology behind why they help people. ...Read more

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What causes ulcerative colitis to flare up?

What causes ulcerative colitis to flare up?

Inflammation: Uc is an inflammatory bowel disease with many triggers. Any trigger that creates an inflammatory response can/will cause a flare up - especially if you are not on maintenance medications. For some patients - even ones in "remission", triggers such as GI infection, systemic illness, significant change in diet and activity, or severe emotional stress can result in a flare up. ...Read more

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How do "colitis" and "ulcerative colitis" differ?

Colitis: There are many forms and types of colitis, some will resolve on their own. Infectious (bacterial), pseudomembranous, ischemic, crohn's, etc. Ulcerative colitis is a specific form of chronic colitis of uncertain cause, diagnosed often by biopsy at colonoscopy. It can be a long term condition needing specific medications to treat & serial colonoscopy to watch the degree of colitis or for dysplasia. ...Read more

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What are the main symptoms of Ulcerative colitis ?

Ulcerative colitis.: Typical symptoms include diarrhea with overt rectal bleed, abdominal pain. Some can present with nausea, weight loss, and fever. There are other associated symptoms and complications, but less frequent. ...Read more

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What are the typical symptoms of ulcerative colitis?

Diarrhea, bloody: Bloody diarrhea is the hallmark of ulcerative colitis, but sometimes multiple loose stools can occur with or without blood. Those affected often have weight loss or failure to thrive. Abdominal pain may occur. Extraintestinal symptoms include eye and joint disorders, and rarely, biliary disease. ...Read more

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What is the definition or description of: ulcerative colitis?

IBD: Ulcerative colitis (ul-sur-uh-tiv koe-lie-tis) is an inflammatory bowel disease (ibd) that causes long-lasting inflammation in part of your digestive tract. Ulcerative colitis usually affects only the innermost lining of your large intestine (colon) and rectum.There's no known cure for ulcerative colitis, but therapies are available that may dramatically reduce the signs and symptoms of uc. ...Read more

Dr. Jonah Essers
532 doctors shared insights

Ulcerative Colitis (Definition)

An inflammatory bowel disease (IBD) that causes long-lasting inflammation in part of your digestive tract. Ulcerative colitis usually affects only the innermost lining of your large intestine (colon) and rectum.There's no known cure for ulcerative colitis, but therapies are available that may dramatically reduce ...Read more


Dr. Scott Bolhack
2,071 doctors shared insights

Ulcer (Definition)

An ulcer is a discontinuity or a break in a body membrane that impedes the normal functioning of the organ of which that membrane is a part. Ulcers are further classified by their location. Ulcers are usually caused by infections, excessive acid production, stress, ...Read more