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Doctor insights on: Remedies For Simian Crease

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What is simian crease?

What is simian crease?

Palm lines: Most folks have two lines across the palm joining the side below the little finger with the space between the thumb and index finger. If only one is present, as in some monkeys ("simians") & in 1% of normal folks, it's a tip-off that the person may have another birth defect, especially trisomy 21, but ultimately it's of no use as the other defects will be obvious. ...Read more

Dr. Lonnie Smith
11 doctors shared insights

Simian Crease (Definition)

is a single line that runs across the palm of of the vhand instead of the 3 creases that are normaly seen appears in 1 out of 30 people more seen in males is often normal may be linked with some other symptoms that define a syndrome like Downs syndrome ...Read more


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What is a simian crease/line?

What is a simian crease/line?

Single palmar crease: Simian crease is a single line that goes across one's palm without a break in the crease or line. In some people this finding can be associated with down syndrome. ...Read more

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What is the definition or description of: Simian crease?

Simian crease: is a single line that runs across the palm of of the vhand instead of the 3 creases that are normaly seen appears in 1 out of 30 people more seen in males is often normal may be linked with some other symptoms that define a syndrome like Downs syndrome or fetal alcohol syndrome ...Read more

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Is the simian crease present in all downs syndrome babies?

No: This is listed is present in about 45% of infants with ds but may be seen at least on one side in 5-7% of normal infants. ...Read more

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If I have some of the physical signs of Down syndrome like a simian crease but don't have down syndrome, am I more likely to have a child with downs?

No: Some of the features seen in down syndrome persons are also seen in other hereditary disorders, and some features are seen in normal people. A normal person can have a single horizontal palmar crease (simian crease), but his simian crease is just a trait he has, and has nothing to do with down syndrome. A normal person with a simian crease is not more likely to have a down syndrome baby. ...Read more

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Is it rare to have a simian crease on both hands?

Is it rare to have a simian crease on both hands?

It's rare: It might be ~ 0.5-1% in the population. It's minor deviation and doesn't mean anything if no other signs or symptoms present. It's commonly associated with down syndrome or trisomy 21. ...Read more

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What to do if I have one simian crease on my hand?

What to do if I have one simian crease on my hand?

Normal variation: The incidence of a single palmar crease varies among different ethnic populations around the world. (14-70%) It is thought to be influenced by positioning in the womb during pregnancy. ...Read more

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What does it mean to have a simian crease on both hands?

What does it mean to have a simian crease on both hands?

May be nothing: If you have only this particular sign and no other signs and well otherwise, it means- nothing. If it comes with the constellation of some other specific signs and symptoms, pediatricians look for certain chromosomal disease, such as down's syndrome. ...Read more