Doctor insights on:
Relationship Between Inflammatory Bowel Diseases And Rheumatoid Arthritis
Is there a connection between rheumatoid arthritis and heart disease/heart attacks? What would it be?
Yes: Rheumatoid arthritis (and any chronic inflammatory state) accelerates formation of atherosclerotic plaques in the blood vessels, and hence is a risk factor for causing heart attacks. Moreover, chronic steroid use (if used to treat ra) may cause metabolic changes that predispose for heart attacks as well. ...Read more
Arthritis is progressive degeneration of one or more joints. Symptoms may include joint pain, swelling, decreased motion, and stiffness. The two most common types of arthritis are osteoarthritis, which is associated first with articular cartilage breakdown with a component of inflammation, and rheumatoid arthritis, which is a systemic autoimmune disorder that affects joint linings first and secondarily ...Read more
Nobody Knows: We are not sure what gets the ball rolling, but autoimmune disease in general is a case of "misprogramming" in which the immune system begins to incorrectly recognize the body's own tissues (joints in the case of ra) as though they were foreign. It then attacks them as it would any invading substance. Smoking definitely raises the risk of ra, though we don't know why! ...Read more
How does the genetics affect rheumatoid arthritis is there any mutations responsible for having the disease?
Perhaps: Rheumatoid arthritis is a mystery as to cause. Genetic factors do not seem to be a certain causal factor, but cannot be ruled out. In recent years there was a study of thousands of sufferers who had in common significant exposure to chemicals used to kill weeds and agriculture pests. ...Read more
Yes: A patient with a positive serology and rheumatoid arthritis can have severe disease. But also people who are seronegative can have severe damage. The highly positive seropositive patient can have more severe rheumatoid disease beyond the arthritis rheumatoid arthritis is a systemic disease of which arthritis is one manifestation. There can be systemic disease of eyes, lungs, heart to name some. ...Read more
see details: It depends somewhat on the joints involved and the severity of the disease activity. The specifics are best discussed with her rheumatologist. ...Read more
Better prognosis: Same disease. Seronegative rheumatoid arthritis (where rheumatoid factor and anti-ccp antibody tests are negative) generally has a better prognosis with a better response to medications and lower chance of joint damage. It is treated similarly to seropositive RA except that some biologic medications (rituximab, abatacept) may not work as well in seronegatives. ...Read moreSee 1 more doctor answer
ESR is 9 mm/h and TSH is 1.03 mIU/L,. Does it mean no rheumatoid arthritis and no automimmune disease?
No: A low ESR may mean that there is no active inflammation but does not rule out the present of an autoimmune disease. On the other hand, if you have an active joint problem and the ESR is normal, then the problem would be unlikely to be an autoimmune issue. TSH is related to thyroid function and is not a gauge for autoimmune disease by itself ...Read moreSee 2 more doctor answers
No: They are unrelated.Get a more detailed answer ›
How likely are diseases like diabetes (both kinds) and rheumatoid arthritis to be passed down if they run in my family? Low right?
The gastrointestinal tract starts at the mouth, travel down the tunnel (esophagus), which connects to the stomach, which then empties into the duodenum, jejunum, and ileum---the three parts of the small intestine (@25 feet). This empties into the colon or large intestine (about 5 feet), which then becomes the sigmoid colon, rectum and out the anus. So, every morsel eaten ...Read more
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