Doctor insights on:
Redox Signaling Molecules
Atomoxetine inhibits serotonin transporter, dopamine transporter and naroephinephrine. What does inhibit mean?
Strattera (atomoxetine): Inhibition is the opposite of stimulation, so the effectiveness is reduced. ...Read more
Which ingredient is the best way fight wrinkles? Retinol, peptides, collagen, stem cells, plancenta, amino acids or vitamin C
Growth factors: We have known since the 70s that retinoids and retinols are great collagen stimulators (which equals wrinkle fighters). In this century, we developed collagen growth factors which are derived from actual human skin and are necessary for collagen to thrive, thus reducing and eliminating wrinkles. Note i did not say "appearance of wrinkles". Skinmedica is my favorite product to contain these. ...Read moreSee 1 more doctor answer
DNA: Genes are made up of nucleic acids called DNA. Those genes are then transcribed into amino acid sequences called proteins. The dystrophin gene is much too large to spell out in a DNA sequence, and its protein is much too large to spell out in an amino acid sequence. Here is a link to some more information on the gene. http://www.ncbi.nlm.nih.gov/gene/1756 ...Read moreSee 2 more doctor answers
Antibiotics: Yes. Great google question. How do antibiotics work? ...Read more
Muscle growth: Many men desire muscular development and this has been so probably for many thousands of years. As a physician I have seen this done consistently well and healthy through sensible weight training which stimulates muscle development through human growth factor, Testosterone and other natural endogenous substances. Avoid exogenous supplements (such as steroids and probably Mechano ) Go natural! ...Read more
InternalBodyControls: If food made us what we are, they we would likely look like what we eat; reality far more complex. The bodies we inhabit: chemical wizards taking apart molecules & reassembling them like fantastic complex tinker toys under internal controls, called biochemistry. Current knowledge: ischemia, ?pressure diff. & flow may trigger complex responses ?angiogenesis & ?inhibitory controls: balance critical. ...Read more
Is it real that januvia (sitagliptin) 100mg made pancreas cells produce more insulin ( made beta cells more active )?
Incretin: Januvia (sitagliptin) is an incretin which inhibits the breakdown of an enzyme called dpp-4. Dpp-4 breaks down glp-1. Glp-1 stimulates Insulin and inhibits glucagon (which raises glucose). Inhibition of glp-1 breakdown means it can stimulate more Insulin and inhibit more glucagon. ...Read more
Mitochondria: It sounds like you have been reading about mitochondria, the powerhouse organelle of cells. These organelles use methods to create the cellular currency of energy, Adenosine triphosphate. You probably read that a portion of the ATP synthase complex is embedded in the mitochondrial membrane. Read about it here: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278611/ You can consult me if you have Q's ...Read more
Are there medicines that work by targeting tau proteins or beta amyloid in Alzheimer's disease? Or gene therapy to replace faulty proteins?
Not yet: This is an active field of research but none are currently available or approved. ...Read more
LDH Isoenzymes lab test results:
LDH total- 153. LD1- 32, LD2-30, LD3, 20, LD4- 8, LD5- 10. Are these results normal? Is the LD1&LD2 ratio abnormal?
Historic test: Matthew, the LDH isoenzyme test is ancient history, almost never ordered nowadays. And your LDH is normal. The old 1-2 ratio is an antique screen for a heart attack, and it's neither sensitive nor specific. I know you're obsessing over the idea that you have lymphoma, and a few websites suggest this as a screening test -- but it's not. Focus on building a life for yourself. ...Read more
Has 'branched chain amino acids' (bcaa) diet suplement some negative affects on human body? (kidneys, liver etc.?)
What things, in the body, regulate glutamic acid? Glutamic acid decarboxylase? Glutamate receptors (nmda, ampa...Etc.)? What else is involved?
It's complicated...: There are some very exciting discoveries on the metabolism of glutamate... There are multiple pathways impacting on things such as gaba neurotransmitter, nitrogen clearance from the liver portal, etc... These pathways play vital roles in survival! please read this.... And email me your questions if you'd like! http://voh.Chem.Ucla.Edu/vohtar/spring04/classes/153ch/pdf/kelly%20and%20stanley.Pdf. ...Read more
If methotrexate works be decreasing folic acid which inhibits cell growth, isn't adding high doses of folic acid defeating the purpose?
Does exercise increase serotonin by stimulating the uptake of tryptophan by brain synaptosomes(sze py.1976)?
-incom. Rt. Bundle branch block
-cholesterol (total), serum by enzymatic method 208
-biochemistry lipid profile : LDL cholesterol, serum 133
Unlikely 2B related: Total and LDL cholesterol look ok, unless you have heart disease or multiple risk factors for heart disease, then LDL goal is <100. Inocmplete rbbb can be normal. Sometimes is just actually a "r s r-prime" pattern in certain electrocardiogram leads- many times a normal finding seen in healthy young military recruits. Incomplete rbbb can progress to a complete right bundle block. ...Read moreSee 1 more doctor answer
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