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Doctor insights on: Recovery After Stem Cell Transplant

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Life expectancy of myeloma patients after autologous stem cell transplant?

Life expectancy of myeloma patients after autologous stem cell transplant?

Myeloma : There are many things that go into predicting life expectancy of somebody with myeloma who has an autologous stem cell transplant. The rough estimate for somebody getting a transplant in first remission is about 6-7 years now. However, this is something your oncologist or transplant doctor can talk to you about with more specific information. ...Read more

Dr. Keith Stockerl-Goldstein
954 doctors shared insights

Stem Cell Transplantation (Definition)

A stem cell transplant may be needed if you have a disease that damages the cells in the bone marrow or if your received high doses of chemotherapy or radiation. Depending on the type of transplant, your procedure may be called a bone marrow transplant, a cord blood transplant, or a peripheral blood stem cell transplant. All three use stem cells, which are immature cells that give rise to specific cell types. Stem cell transplants are similar to blood transfusions and generally ...Read more


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What are the survival rates for cll cancer after donor stem cell transplant?

What are the survival rates for cll cancer after donor stem cell transplant?

Select patients: Allogeneic (donor) stem cell transplants can be conducted using less intensive (non-ablative) regimens with excellent results for patients with CLL. It is not the first line of therapy, since patients can have remissions of several years with simpler therapies. Fatal complications still may occur in 25% of patients, but unlike other treatments, the remainder have a good chance of being cured. ...Read more

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What's involved in allogeneic stem cell transplantation?

What's involved in allogeneic stem cell transplantation?

Donor matching.: This involves two people: the (healthy) donor and the (patient) recipient. Donors must have a tissue (hla) type that matches the recipient. Matching is performed on three or more loci of the hla gene, and a perfect match at these loci is preferred. Even with this, immunosuppression is often needed due to graft vs host disease. ...Read more

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How risky are stem cell transplants?

How risky are stem cell transplants?

Stem Cells: Stem cell injections are now being used to treat painful joints (shoulders, hips, etc), Alzheimers, ALS, Lyme, Cerebral Palsy, etc. Still there are not great published studies proving its benefit in many of these conditions. We have been using limbal stem cell transplants in eye surgery for years with excellent results. See eyedoc2020@blogspot.com: depends on where the stem cell is from & for. ...Read more

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For leukemia has anyone had a successful stem cell transplant?

For leukemia has anyone had a successful stem cell transplant?

Many: There are different types of leukemia, lymphoid vs myeloid, acute vs chronic. Some leukemia can be treated for chemotherapy only, some leukemia will need to be treated by stem cell transplant. The outcome of stem cell transplant is different depending on what type of leukemia a patient has. However, stem cell transplant has an established record to cure leukemia. ...Read more

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What is the goal/ predicted outcome of autologous stem cell transplantation studies for ms?

What is the goal/ predicted outcome of autologous stem cell transplantation studies for ms?

Multiple sclerosis : Researchers are optimistic. Yet, no proven efficacy as of yet. Mortality is down to 1-2%. Check following site: http://www.Ncbi.Nlm.Nih.Gov/m/pubmed/18565456/. ...Read more

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Why are umbilical cord stem cells sometimes uses along with donor cells in an allogeneic bone marrow transplant?

Why are umbilical cord stem cells sometimes uses along with donor cells in an allogeneic bone marrow transplant?

One of the other: Stem cells can be obtained from 3 different sources: from Bone marrow of the Donor, blood of the donor or stem cells from umbilical cord. But we have to give an adequate number(Dose) of stem cells in order to have full protection. So combining them may only be needed because of inadequate number of stem cells from one of the sources ...Read more

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Stem cell transplant for ovarian cancer--will it prolong survival rate?

Stem cell transplant for ovarian cancer--will it prolong survival rate?

Yes possible: With out knowing stage and cell type of ovarian cancer , in general high dose chemotherapy with autologous ( patients own ) stem cell transplantation is promising to prolong the life, cure is not near yet, as most of the tumors are drug resistant ( or right drug is not there ) and have residual tumor in the body. ...Read more

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Pancreatectomy with autologous islet cell transplantation: what does this mean?

Pancreatectomy with autologous islet cell transplantation: what does this mean?

Saving insulin: When an islet cell transplant has to be performed it means that the pancreatectomy was total. The pancreas is an exocrine (digestive juice) and endocrine gland from the Islets of Langerhans. When all are removed, islet transplant helps retain endocrine activity including insulin production. ...Read more

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Has anyone had a successful stem cell transplant for cancer?

For certain diseases: Stem cell transplants (bone marrow transplants) are often successful at treating cancers of the blood and bone marrow such as leukemias, lymphomas and multiple myeloma. They can also be used to treat some disorders of the red blood cells and immune system. ...Read more

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What is the recovery time for bone marrow transplant?

What is the recovery time for bone marrow transplant?

Sometimes shorter: It depends on the type of transplant. If you get your own cells (autologous) recovery is generally 3-6 months. For a transplant from a donor (allogeneic) some patients are back to work in 6 months but more typically return to work is 6-12 months but it can be longer if there are delayed complications. ...Read more

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Is it reasonable to have second autologous stem cell transplant for myeloma?

Yes: This is a very difficult question today because every situation with myeloma is different. We do not double transplant all myeloma patients like we have done in the past. It is sometimes reasonable if the first was previously successful and donor cells remain. We now have so many treatments for myeloma that sometimes we do an allogeneic transplant or treat with other drugs (velcade, carfilzomab. ...Read more

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Could stem cells prevent need for a bone marrow transplant?

Could stem cells prevent need for a bone marrow transplant?

NO: Bone marrow transplant is a stem cell procedure. This can be your own bone marrow stem cells, a family member or match for bone marrow or embryonic stem cells. ...Read more

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When is a stem cell transplant used nowadays?

Several diseases: Including acute leukemia, multiple myeloma, some forms of resistant lymphoma, aplastic anemia and a few other rare disorders. ...Read more

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How good is the bone marrow transplant for a sickle cell patient?

How good is the bone marrow transplant for a sickle cell patient?

Very!: If a patient with sickle cell disease has a well-matched donor and gets through the transplant procedure safely with good engraftment of the donor bone marrow, they will be converted to normal or sickle trait depending on the donor. ...Read more

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What are complications post- bone marrow transplant?

What are complications post- bone marrow transplant?

Many!: Risks are lower if you had your own cells (autologous) or a twin's cells (syngeneic), and higher if you had someone else's (allogeneic). There are short-term and long-term risks. Risks include graft vs host disease, infections (some fatal), liver problems, bleeding, cataracts, infertility, heart damage, lung damage, kidney damage, and others. ...Read more

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How to cure blood cancer after bone marrow transplantation?

How to cure blood cancer after bone marrow transplantation?

Unclear ?: Are you saying that the bone marrow transplantation did not cure the blood cancer? If that is your question, then the choices are limited. You should consult another bone marrow transplant experrt and seek his/her input. Bone marrow transplant can sometimes be repeated...As one option. There are also new/experiemntal drugs which can still help even after failure of the transplant. ...Read more

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How long are you out of commission after a stem cell transplant?

It depends.: The recovery from autologous transplant is much quicker than allogeneic transplant, typically 90 days or so. Recovery from allogeneic stem cell transplant is more difficult to predict, as there are more potential complications, a much slower recovery of immune function that requires avoiding crowds and infection risk for a much longer time. Age and pre-transplant status also play a role. ...Read more

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What is the recovery period of bone marrow transplant?

It depends what you: Mean by recovery. Recovery takes many forms after a stem cell transplant. Neutrophil recovery tends to preceed platelet recovery. There are other issues thatnaffect recovery, such as the nature of the prep regimen, the stem cell dose, auto vs unrelated donor, the degree of immune suppression required to maintain the graft, etc. Work closely with your transplant docs during this period of recovery. ...Read more

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Dr. Chad Levitt
3 doctors shared insights

Transplant (Definition)

In medicine: a transfer from one body or body part to another of an organ (liver, heart, lung, kidney, pancreas bowel) or tissue (hand, face, hair). The immune system fights foreign invaders (like infections) so it will reject transplants from other people (allotransplants) because they look like infections. So transplants usually require drugs to ...Read more


Dr. Steven Griggs
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Stem Cell (Definition)

The capacity to "grow up" or differentiate to produce mature cellular elements. In blood production rbc, WBC and platelets. Fundamentally, stem cells can also self-replicate and thus provide a pool of ...Read more