Doctor insights on:
Reclast Vs Zometa
Yes: Reclast (zoledronic acid) is an intravenous form of a bisphosphonate. Bisphosphonates (including fosamax, actonel, boniva) are the most common meds used to treat osteoporosis. They all work in a similar way. The major advantage to Reclast (zoledronic acid) is that it is given once yearly, and does not have GI side effects like the ones taken orally. There may be a slightly higher risk of atrial fibrillation with this drug. ...Read more
These are 2 options: Xeloda (capecitabine) - is an oral chemotherapy drug that can be used for certain metastatic cancers alone or in combination with other chemotherapy drugs as palliative treatment. Zometa - is used in a situation where cancer has spread to the bones. Its not chemotherapy but a bisphosphanate, a medication used to prevent further weakening of bones by cancer and prevent fractures. In some situations both are given. ...Read more
Prolia: Both medications are anti-resorptive, meaning they prevent breakdown of your bone. Reclast (zoledronic acid) has been used for longer so has more side-effects that are known. It also can not be used if you have kidney problems. Prolia is an injection every 6 months (vs. 12 months with reclast). Both medications tend to be very well tolerated. ...Read more
Adrenal Insuf, NO immunity, MANY med iss. Finished Forteo DONT want 2 take Reclast/Prolia. Endo mad at me. But, is there anything else?
This is a LOT of: information. I see that you make many submissions on Health Tap. It is important to remember that we can NOT diagnose or make medical / medication recommendations/ treatment on the general Health Education portion of HealthTap. Health Tap Prime or Concierge can be used for that purpose. ...Read more
For me, 3 yrs ago Reclast=5% improvement, Prolia for 2 yrs=little improvement, but 10% LOSS hip neck! Why? And, now must be off for 3 yrs, scary! Thx!
Treating osteoporosi: Reclast (zoledronic acid) is an antiresorptive medication (like Fosamax, Boniva, etc) that is given IV. It will prevent further loss but will not rebuild bone. 5-10% increase/decrease is likely within the margin of error of a DEXA scan. Recombinant human parathyroid hormone rPTH (Forteo) is an injectable medication that does rebuild bone and increase density. rPTH cannot be given with a history of cancer. ...Read more
Took fosomax for 7 years with little benefit; then no meds for 2 years. Which has best risk/benefit ratio: reclast, (zoledronic acid) prolia, fortero, foxomax?
Not uncommon: Xeloda (capecitabine) is a chemotherapy drug related to 5-fu. It is a tablet and is used by itself in the elderly and in combination with other drugs for breast cancer. It is relatively well tolerated. Zometa is a bisphosphonate designed to strengthen bone like drugs for osteoporosis. In metastatic cancer its job is to reduce the liklihood of fracture and other problems in bone. ...Read more
I am on yearly Reclast Infusions due to malabsorbsion (sbs). I am still getting fractures at least once a year. can I get Reclast more often?
Yes you should:
Reclast has been used for several conditions including patients with cancer where it has been used once monthly to once every 3 monthly.
For Osteoporosis it has been used once every 6 months as a preventive measure. So you should ask her your doctor to reassess your condition and ask for infusion more often, either at 6 month or even 3 monthly for one year and then reduce it to once every 6 months ...Read more
Is it complicated to have a tooth extracted if you've had a reclast (zoledronic acid) infusion? Last infusion was 2011.
Two issues: It may or may not be complicated based upon the condition of the tooth and supporting structures. There should be no problem in regards to the medication taken years ago at this point in time. ...Read more
Myasthenia Gravis HAVE to be on osteoporosis med. I'm severe!Interactions with Reclast (zoledronic acid) IV & MG? Scared once in system what if it flares my MG?
Osteoporosis meds: One issue with some medications used in rheumatoid arthritis, is presence of anti-tumor necrosis factor action, which can make MS worse, but this mechanism does not seem salient in osteoporosis drugs, and these would be very unlikely to adversely affect Myasthenia, as Reclast (zoledronic acid) does not affect acetylcholine in any profound way. Discuss further with your doctor, but I do NOT see a problem. ...Read more
Which drug would you choose for osteoporosis of hip prolia or reclast (zoledronic acid) what is better tolerated less side effects?
Depends: Both drugs are effective in the treatment of osteoporosis involving the hip. Prolia is likely to work better than reclast, (zoledronic acid) though there are no head to head studies comparing the two. Prolia is typically used in people who have had a previous fracture (spine, wrist), or have very severe osteoporosis. Both are well tolerated with few side effects. Prolia is given twice yearly, Reclast (zoledronic acid) once yearly. ...Read more
My doctor recommended reclast (zoledronic acid) for" convenience." i'm only concerned about the risks/benefits of a drug. Should i choose prolia or fosomax instead?
Have myasthenia gravis, severe osteoporosis.Scared of "another med" to treat osteo and it NOT flare/worsen MG!! Reclast, (zoledronic acid) Proliva, Forteo?try shot 1st?
Osteoporosis : unfortunately there's no easy answer. We are lucky to have many options for osteoporosis and each drug comes with risks and benefits. Your medial history, labs, x-Rays & DEXA have to be factored in before individualizing your treatments. Please discuss with your doctors. Best wishes. ...Read more
I have had one IV infusion of reclast (zoledronic acid) and need dental extractions. And woul like two implants is this safe?
Statistically, Yes: If you take research seriously, and most of us in the profession definitely do, then there is little chance of osteonecrosis of bone from a single IV dose of reclast (zoledronic acid). That said, your chances are higher than someone who does not take reclast (zoledronic acid), and the IV form (versus the oral pill) is also a more elevated risk, statistically. Overall, talk with your dmd and get his/her take, but you should be fine. ...Read moreSee 1 more doctor answer
Why is it that after a phase of zometa, the doctor asks the patient to treat their teeth and then continue to the second phase?
I took a reclast (zoledronic acid) infusion feb. 27 and i now need a tooth removed due to a cavity. Is it safe to have it removed?
It depends...: On whether you have taken any other osteoporosis medication before this last Reclast (zoledronic acid) injection, including another dose of Reclast (zoledronic acid) previously. After reviewing your history with these medications, your oral surgeon can discuss the potential risks you may face and when the extraction might be safest. If delay is suggested, a root canal could buy you time. ...Read moreSee 2 more doctor answers
Had 1st reclast infusion yesterday
Felt ok till next day
Was it ok that I exercised this morning 1 hour cardio 20 min light weights ?
Exerciae: Typically exercise is beneficial for any condition ...Read more
Follow-up question, while taking the Gemzar and Zometa,experiencing mouth sores,makes my mouth incredibly dry. Is there anything I can do to ease this?
My grandma is in the hospital she has flu like symptoms and is severely confused not irinating much she had the IV reclast (zoledronic acid) yesterday. What's going on?
Delerium: Your grandmother is experiencing a common problem in elderly patients when hospitalized- the medical term for her confusion is "delerium" ; she has several risk factors: age, acute illness, dehydration, fever, unfamiliar environment (hospital) ; probably medications. It is unlikely the Reclast (zoledronic acid) is causing her confusion. Dementia also increases her risk- hopefully, she will improve on discharge. ...Read moreSee 2 more doctor answers
Took fosomax for 7 yrs with little benefit (slightly worse each yr), then no meds x2 yrs. Which has best risk/benefit ratio: reclast, (zoledronic acid) prolia, fosomax? Ctx test results >300 so md eliminated forteo.
Resuming treatment for myeloma with rev and dex. Recent dexa scan says I have bones of young adult! Haem insists I have zometa infusions. Why?
More benefit: Zoomed makes the bone harder. Myeloma cells live in the bone marrow next to the bone and they bore into the bone. By replacing a mineral of the bone with Zometa the bone become less tasty to the digesting cells that then feed the myeloma.Dex also can soften bones. So these are good reasons to take Zometa but don't overdo it as too much can make the bone too hard. ...Read more
I took zometa IV 7yrs ago. Now I have osteoporosis & was prescribed an oral similar drugs. Will this cause osteonecrosis of jaw ? My tooth hurts!
See dentist: You can have dental treatment while you are taking medications for osteoporosis. Dental care is extremely important and you want to save your teeth if possible. Your dentist will discuss the very low risk of osteonecrosis after extractions with you. Try to treat the tooth rather than remove it. ...Read moreSee 4 more doctor answers