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Doctor insights on: Rbc Folate Level High

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I live in canada and recently had blood work done my RBC folate (folic acid) level was 2423 is this too high? What could it mean?

I live in canada and recently had blood work done my RBC folate (folic acid) level was 2423 is this too high? What could it mean?

Likely no problem.: Folate (folic acid) in the rbcs is a test done to see if a person is folate (folic acid) deficient. For pregnant women, this could mean neural tube defects in the newborn if it is low, and megaloblastic anemia and malnutrition in adults. Your levels are well above the adult range of 150-450 ng/ml/cells (340-1020 nmol/l/cells), and you should have nothing to worry about. It is water soluable and excesss is urinated out. ...Read more

Folic Acid (Definition)

Folic acid, AKA folate (folic acid) (vit B9), is recommended for all women wanting to get pregnant -- 0.4mg (400mcg) daily, which is important for preventing birth defects like spina bifida. Women w/ a hx these disorders should take 10x that amt daily -- 4mg (4000mcg) through the 3rd month of pregnancy. It won't affect fertility, chances of conception/twins, or periods. ...Read more


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Is high RBC folate (folic acid) associated with vitamin B12 deficiency?

Not likely: Please consult this site for info in this topic. Folate (folic acid) and B12 are needed for efficient red cell production and other functions, but lack of one does not increase the other.
http://www. Webmd. Com/diet/folic-acid. ...Read more

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Hematocrit. 403, magnesium. 77, calcium 2.33, b 12 1107, RBC folate (folic acid) 2168, ferratin 74, testosterone. 9, vit d 127. Are these normal?

Hematocrit. 403, magnesium. 77, calcium 2.33, b 12 1107, RBC folate (folic acid) 2168, ferratin 74, testosterone. 9, vit d 127. Are these normal?

Check with your doc: There are abnormal results. Check with the doc who ordered these tests and discuss these results = there was a reason to order these tests. ...Read more

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High MCV & MCH for few years. 2 yrs of low rbc. New CBC has folate (folic acid) & calc. Defic., low bun. 2 mnths ago found soft clavicle lymph "mass". Esophag spsm?

Lots of info: Here. Possible relevance undetermined. From a heme standpoint high MCV and folate (folic acid) deficiency would go together. Folate (folic acid) supplements would be indicated. Cannot relate to esophageal issues. ...Read more

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High MCV and MCH for a few years. 2 yrs of low rbc. Recent CBC now has folate (folic acid) & calc. Defic., low bun. 2 mnths ago found soft clavicle lymph "mass". Esophageal probls. & hypogammaglobulinemia. Help?

High MCV and MCH for a few years. 2 yrs of low rbc. Recent CBC now has folate (folic acid) & calc. Defic., low bun. 2 mnths ago found soft clavicle lymph "mass". Esophageal probls. & hypogammaglobulinemia. Help?

Needs more info: Difficult to say based on limited info. High MCV likely due to low folate (folic acid) (did you check b12?). Low BUN is good, so no worries. If you have a clavicular lymph node it needs evaluation for sure. See your doctor! ...Read more

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I have enlarged RBCs, and low ferritin/iron. I'm homozygous MTHFR (never processed folate or B12, correctly). Is there a dr who understands both things?

I have enlarged RBCs, and low ferritin/iron. I'm homozygous MTHFR (never processed folate or B12, correctly). Is there a dr who understands both things?

Hematologist: I don't know where you live, but your primary care doctor can refer you to a specialist in hematology. If you live near a University Medical center and your insurance covers it, that is where I suggest being evaluated ...Read more

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Dad has low hemo rbc hemat since 2011. Got worse. Can he still have iron def even if mcv is normal. Doc never gave ferritin test. B12/folate normal.

Microcytic anemia: Iron deficiency causes a "microcytic anemia", meaning the red blood cells are smaller (measure by the mean corpuscular volume or MCV). If there is simultaneously a macrocytic anemia, which can be caused by low folate or low B12, then the average MCV could be normal but there would be both smaller and larger cells (and the spread of cell sizes, measured by the RDW would go up). ...Read more

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I had my Blood result Rbc:occasional macrocytes seen Impression: vitamin b12/folate definitely should be excluded My hemoglabin is okay What it mean?

Hard to say: When RBC are large it can be due to B12 or Folate (folic acid) deficiencies. Sometimes alcohol will fool the automated systems and of course there are other causes. It is worth checking out even if you are not anemic per se. ...Read more

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I had my blood result it says rbc:occational microcytes seen Impression: mild vitamin b/folate deficiency should be excluded... What thus it mean?

Recheck report: Microcytes associated with iron deficiency
Macrocytes with folate (folic acid) & B12 deficiency
What is your Hemoglobin level?
Do you take any meds for stomach acid? ...Read more

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Symptoms of anemia but blood tests normal (iron, B12, folate, (folic acid) RBC, etc). What other common conditions would a doctor look for?

Symptoms of anemia but blood tests normal (iron, B12, folate, (folic acid) RBC, etc). What other common conditions would a doctor look for?

Thyroid?: It depends on what you mean by "symptoms of anemia." Endocrine / infectious / oncologic conditions could all cause general weakness / low energy, if that is what you mean. Can ask follow up with more specifics. ...Read more

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Anemia:rbc-3.7, hct-35.4, fer-50, iron-54, tibc 268, iron sat 20%, PLT 222, retic. 6%, potas 5.2, B12 1500, folate (folic acid) 24.8. College athlete weight gain, fatig?

? Not anemic: Your rbc is low, but hct is probably at the bottom of normal. The other lab values are all normal. This discrepancy between rbc and hct usually means either your red cells are unusually big, or something is interfering with the counting. This can happen with a cold agglutinin (red cells clump in the cold), excessive alcohol, liver problems, or low thyroid. Given other symptoms, check thyroid. ...Read more

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36 weeks preg. Iron 66, feritin 78.5, b12 207, folate (folic acid) 13, rbc 4.22, hb 10.4, hct 32, wbc 9.16, plt 169. anemic since 2 years. Is this bone marrow problem?

36 weeks preg. Iron 66, feritin 78.5, b12 207, folate (folic acid) 13, rbc 4.22, hb 10.4, hct 32, wbc 9.16, plt 169. anemic since 2 years. Is this bone marrow problem?

Probably not. .: First, please be assured that a Hb of 10.4 is not a danger to you or to the baby. The Bone Marrow makes 3 types of cells (WBC's, Platelets, RBC's). Your platelets and WBC's are normal. If you or your doctor were concerned about a bone marrow problem (i.e. bone marrow suppression), you can also get a test called a Reticulocyte Count. Best of luck! ...Read more

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What happens if you have an abnormally high B12 level and high folate (folic acid) level?

What happens if you have an abnormally high B12 level and high folate (folic acid) level?

High B12 Folate (folic acid): I understand your concern.

Researchers in Denmark have found that higher than normal levels of B12 may indicate a person is at risk of developing Lung, Colon and Liver cancer.

National Institute Health Research stated-High folate (folic acid) does not appear to increase the risk of anemia among healthy people with low B12 levels

See your physician for evaluation tests and treatment ...Read more

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Hi. I have folate deficiancy at 2. but my feritin levels are very high. I have been given folic acid to take everyday. Are the two linked?

Complete workup: You need to find out why you're folate (folic acid) deficient. This may simply involve modifying your diet to include more folate (folic acid)-rich foods. However, a very high serum ferritin warns of hemochromatosis. This is deadly if neglected but easily managed. They are not connected. Insist on a full explanation from your physician. ...Read more

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What would cause elevated B12 and folate (folic acid) levels?

What would cause elevated B12 and folate (folic acid) levels?

Stop worrying: We see these from time to time. They are no cause for concern. Reference ranges are set for the vast majority of people. Just be happy. Elevated B12 has some arcane significance in hematology but it does not apply to healthy people. Just be glad. ...Read more

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Are elevated B12 and folate (folic acid) levels bad? Cause of this? How to bring them down to normal levels?

Are elevated B12 and folate (folic acid) levels bad? Cause of this? How to bring them down to normal levels?

Needs evaluation: High B12 & folate (folic acid) is not dangerous per se (these vits. Have no known toxicity)& may not be serious, but high B12 may paradoxically be a sign of B12 deficiency & may also be caused by acute or chronic liver disease or leukemia, so deserves further evaluation-see http://healthyeating. Sfgate. Com/high-vitamin-b12-serum-levels-6037.Html
high folate (folic acid) may be a sign of B12 deficiency or blind loop syndrome. ...Read more

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Had bloods done I've got high folate (folic acid) levels of 20:1 what does this mean I'm male b12 & hemoglobin are OK?

Normal: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, Serum folate (folic acid) level of 20.1 is perfectly normal and is not a cause for any concern. ...Read more

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Are elevated B12 and folate (folic acid) levels a problem? My most recent blood work showed these both to be high...Any danger?

Are elevated B12 and folate (folic acid) levels a problem? My most recent blood work showed these both to be high...Any danger?

How high?: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, it would have helped to have the actual values of the results. In general high values for folate and B12 are not a problem. ...Read more

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My mom is 66 and has elevated homocysteine levels. B12 and folate (folic acid) are normal. On BP meds but systolic still high. Any thoughts or suggestions?

MTHFR: There are several causes for high homocysteine levels but the most common is the mthfr gene mutation. The mutation affects the metabolism of folic acid, which utilizes b12. Often, blood levels look normal but the body is actually not able to process the vitamins so the homocysteine remains elevated. Also, the B12 and folate might look "normal" but might not be optimal. More tests are needed. ...Read more

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My recent lab tests came back with Iron level of 30, transferrin of 20%, low vitamin D, high B12 and high folate. Is this cause for concern?

My recent lab tests came back with Iron level of 30, transferrin of 20%, low vitamin D, high B12 and high folate. Is this cause for concern?

Lab values: Low iron exists. Low vitamin D exists. These are not major threats but should be remedied. Take iron daily as a supplement. And add Vit d as a supplement. A real good iron pill is vitron C A good dose of Vit D is 1000 units per day ...Read more

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Folate (folic acid) 53/B12 1500/Both 1.5-2xUNL. Are these levels good for pregnancy? I know low levels link to risks of birth defects. What about high levels?

Folate (folic acid) 53/B12 1500/Both 1.5-2xUNL. Are these levels good for pregnancy? I know low levels link to risks of birth defects. What about high levels?

Needs further eval: If you are reporting the usual units for folate (folic acid) and B12, then they are high. The most likely explanation is that you are taking these in supplements anticipating pregnancy. If so, you are taking too much and should cut back to only recommended intake. If you are not taking supplements or medications, this needs prompt evaluation as it could be related to liver, kidney or bone marrow problems. ...Read more

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I have a low folate (folic acid) level a high WBC and alopeciA suddenly, and high Bp I've also lost 50 0/0 of my hearing, yet still all the Drs don't have clue?

I have a low folate (folic acid) level a high WBC and alopeciA suddenly, and high Bp I've also lost 50 0/0 of my hearing, yet still all the Drs don't have clue?

One diagnosis?: I'm not aware of any unifying diagnosis that could tie all those diverse symptoms together into one neat package. Low folate (folic acid) can cause low WBCs. High BP is very common and likely an unrelated problem. I think the approach here should be to address each issue: supplement folate (folic acid), search for infection, treat HTN, and go thru a list of causes for alopecia (there's a bunch of them). Best wishes. ...Read more

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I am 7 weeks pregnant. Haemoglobin level 152g/L. Is it high for pregnancy? Platelets and MCV all normal. Serum folate 25.2 on folic acid, also high.

Probably normal: Your hemoglobin of 15.2 is fine for being 7 weeks pregnant. The numbers will decrease moreso in the 2nd and third trimesters. You should be on a multivit (prenatal) which has folic acid in it. Folic acid is very important in pregnancy.

Hope all is well otherwise. Good luck with your pregnancy! ...Read more

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12 weeks pregnant. Have high folate (folic acid) serum levels blood test-is this ok or dangerous? Do I stop vitamins? (takin pregnacare max with calc vit d &omega

12 weeks pregnant. Have high folate (folic acid) serum levels blood test-is this ok or dangerous? Do I stop vitamins? (takin pregnacare max with calc vit d &omega

TOTALLY SAFE: There is absolutely no known toxicity from folic acid. It is far better to have high levels than low. This just means you have more in your blood than most people but, again, this is not harmful in any way and will protect your baby from birth defects. ...Read more

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Previous ida. Now high B12 and folate (folic acid) levels. Ferritin result is not back. Significant hair loss and sob? Could high folate (folic acid) mask B12 deficiency? Thx

Previous ida. Now high B12 and folate (folic acid) levels. Ferritin result is not back. Significant hair loss and sob? Could high folate (folic acid) mask B12 deficiency? Thx

Masks anemia only: High folate (folic acid) can mask megaloblastic anemia caused by B12 deficiency but does not affect B12 levels. The high B12 levels you have are proof that you don't have B12 deficiency. I don't know what ida is.
Hair loss ; sob can have many causes. It sounds like you are being evaluated for possible causes. ...Read more

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What would cause a slightly elevated B12 and folate (folic acid) level on complete blood count?

What would cause a slightly elevated B12 and folate (folic acid) level on complete blood count?

Dietary supplents: The most likely cause of elevated B12 and folate (folic acid) is dietary or parenteral supplements. Other sources of B12 and folate (folic acid) are the diet itself. Consult your doctor for more information. ...Read more

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58+ F Hb 10.8, RBC "Predominantly macrocytic normochromic with macroovalocytes". Ferritin 100 ng/ml, B12 894 pg/ml, Folic Acid 12.3 ng/ml. Why Anemia?

58+ F Hb 10.8, RBC "Predominantly macrocytic normochromic with macroovalocytes". Ferritin 100 ng/ml, B12 894 pg/ml, Folic Acid 12.3 ng/ml. Why Anemia?

Hg 10.8 macrocytic: Tested methylmalonic acid? Homocystine,? they are usually elevated before B12 goes down, though your B12 is pretty normal. Are you on any medications? metformin? HIV? alcohol? Hypothyroidism, liver disease, COPD, G6PD, hemolysis, malabsorption (usually have low B12 as well) can cause it as well.

http://www. Aafp. Org/afp/2009/0201/p203.html
f/u/ w/ hematology ...Read more

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Rbc lo. Hgb, hct ok. Mch & MCV hi. Ferritin ok. B12 & folic acid hi. D lo. Thyroid ok. Rf hi. Repeatable. Tired, weak and unfocused. Cause?

Additional info: What are the actual number values associated with the rbc, hgb, hct, mch, and mcv? This will help establish significance of these high or low values. Do you have relatives with RA or other autoimmune disease? Do you have any history of hepatitis or liver disease (can cause simultaneous high rf and high mcv)? Are there other lab test results for autoimmune disease (ana)? ...Read more

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Very fatigued for about a month. Labs WBC 3.5, RBC 4.15, RDW 14.6, PLT 136, hgb 12.6, hct 12.6, MCV 90, mchc 33.6, B12 824, d 33. Genetic testing = poor converter of folic acid. Could I be anemic?

Very fatigued for about a month. Labs WBC 3.5, RBC 4.15, RDW 14.6, PLT 136, hgb 12.6, hct 12.6, MCV 90, mchc 33.6, B12 824, d 33. Genetic testing = poor converter of folic acid. Could I be anemic?

Likely: You are borderline anemic but your blood test also showed a low WBC count. I would recommend that the WBC be repeated and if it remains low, a hematology consult would be desirable. ...Read more

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What does it mean to have high folate (folic acid)?

What does it mean to have high folate (folic acid)?

Taking too much: Too much folate (folic acid) is generally not a problem, but you might cut back on the vitamin supplementation. ...Read more

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What can high folate (folic acid) and B12 tests mean for adults?

What can high folate (folic acid) and B12 tests mean for adults?

High folate (folic acid) and B12: Although low levels of folate (folic acid) and vitamin B12 can cause serious medical problems, there is no problem whatsoever with having high levels of these vitamins. ...Read more

Dr. Kristi Woods
647 Doctors shared insights

Folate (Definition)

Folate is a vitamin which is a kind of nutritional agent ...Read more