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Doctor insights on: Rare Sarcoma Cancer

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I have a rare cancer called neurofibroma sarcoma. What are the chances my kids can get it?

I have a rare cancer called neurofibroma sarcoma. What are the chances my kids can get it?

Possibility: Neurofibrosarcomas have a genetic basis with a possible abnormality in chromosome 17. Fifty percent of these tumors are associated with a familial condition known as neurofibromatosis, which causes tumors of nerve support cells (including Schwann cells). Resection of the tumor after possible shrinking is a consideration. The sarcomas in general tend not to respond well to chemo. Rather RT post op in the larger lesion is a consideration. ...Read more

Dr. Barry Rosen
4,214 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Found out I have a rare cancer called neurofibroma sarcoma. what are the chances my kids can get it?

Found out I have a rare cancer called neurofibroma sarcoma. what are the chances my kids can get it?

A possibility: neurofibrosarcomas are peripheral nerve malignant lesions with a tendency to metastasize. They can occur in young children and are frequently associated with café-au-lait spots on the skin. There is a congenital form of disease, von Recklinghausens, where diffuse benign cutaneous neurofibromas are found and which have a high conversion rate to malignancy. Such tumors do occur on extremities. ...Read more

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How do people get sarcoma cancer?

How do people get sarcoma cancer?

Usually random: Sarcomas are bone and soft tissue cancers. Generally, these occur because of random events in most patients. However things like radiation exposure can increase the risk of bone and soft tissue sarcomas particularly with higher dose radiation like used for treatment of other cancers. There are some genetic diseases like li-fraumeni that can result in getting a sarcoma and other cancers. ...Read more

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Anyone know about sarcoma and whether it is a serious cancer?

Anyone know about sarcoma and whether it is a serious cancer?

Yes they are: Sarcomas are embryo logically mesodermal tumors like muscle bones , supporting tissue etc, if they are not detected early and not treated they are just as bad as carcinomas, . They tend to spread by blood stream not by lymphatics , usually resistant to radiation. ...Read more

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I have just seen this a sarcoma is a cancer that arisesthe same thing as ectodem?

I have just seen this a sarcoma is a cancer that arisesthe same thing as ectodem?

Terminology: Forget the arcana of germ layers in cancer nomenclature. Sarcomas are cancers that have, for their cell of origin, a connective tissue cell -- bone, cartilage, undifferented mesenchyme, fat, smooth / striated muscle, endothelium. By convention, cancers arising from blood elements, lymphocytes and mesothelium are given non-sarcoma names. ...Read more

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What kind of cancer is kaposi's sarcoma?

What kind of cancer is kaposi's sarcoma?

It used to be seen: In elderly men of mediterranean origin, a purple raised lesions most commonly on extremities, and it was quite rare. However, it became the hallmark skin finding in the early aids epidemic, as immune systems deteriorated, these lesion occurred all over bodies. Interestingly, as immune systems recovered, many of these lesion involute indicating a strong importance of immunity. ...Read more

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How does the rous sarcoma vrius cause cancer?

Oncongene insertion: Rous sarcoma virus inserts a gene (src) into the dna of the animal it is infecting. This gene enables the uncontrolled replication of the cells it infects. Cancer arises in the tissues from this uncontrolled growth. ...Read more

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What are the differences between sarcoma and carcinoma cancers?

Derivation: sarcomas arise from supportive tissues of the body. They are found in and derived from muscle, fibrous tissue and fascia, fat, nerve, blood vessel and bone. Spread is to liver and lung. Carcinomas arise from secretory and epithelial membrane spreading first to regional nodes as seen with breast, colon and lung. They respond differently to chemo. ...Read more

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When do I need to stop taking chemotherapy for karposi sarcoma cancer?

When do I need to stop taking chemotherapy for karposi sarcoma cancer?

Tough question: The first therapy is haart, highly active antiretroviral therapy. Once the the viral load is down, commonly the kaposi's sarcoma resolves. If it does not, then Paclitaxel is a good chemotherapy for this. The length of therapy depends on the response. Hope this helps. ...Read more

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Is it true that chemotherapy makes it worse if you have sarcoma cancer?

No: Chemotherapy does not make sarcoma worse. However, some kinds of sarcomas are quite resistant to many chemotherapies. Other types like ewing's sarcoma, osteosarcoma, rhabdomyosarcoma, and even synovial sarcoma can respond to chemotherapy very well and chemo is an essential part of the the cure of these diseases. There are also new drugs available that can slow the growth of more resistant types. ...Read more

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Dr. Payam Mehranpour
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Sarcoma (Definition)

By definition, it is malignant (i.e., being locally invasive and at least theoreticlally capable of metastasizing), and arises from / mimics muscle or connective tissue elements that are not marrow or immune / white cells. The sarcomas are a tremendously varied and troublesome family of tumors, though thankfully less common than carcinomas and the leukemia / ...Read more