Doctor insights on:
Raloxifene Side Effects
Perhaps: Evista (raloxifene) if taken to reduce breast cancer in post-menopausal women is usually taken just for 5 years but there is no limit number of years if taken for osteoporosis. There may be an increase risk of ovarian cancer the longer it is taken. Increased risk of stroke or blood clots is not necessarily related to duration of intake. ...Read more
Strontium ranelate, tamoxifen, raloxifene - are the side effects the same regarding dvt, heart attacks etc &which would offer more protection for bone?
Raloxifene: Of all the products you mentioned, Raloxifene has the most well established record and is fda approved to improve bone density. Unfortunately, its ability to do so appears weaker than bisphosphanate products, teriparitide (forteo) of prolia. The other products you mentioned are not fda approved bone building products. Strontium is not available in the us as an anti-osteoporotic agent. ...Read more
Blood clotting: The most common is worsening of menopausal symptoms, but blood clots (particulary in the legs) are much more serious. Do not use if you're a smoker or have a problem with clotting. ...Read more
Why are prolia and raloxifene considered by some to be better alternatives to the other treatments for osteoporosis and are the side effects common?
Which is the safest osteoporosis treatment between raloxifene and strontium ranelate or are they equal in similar side effects?
Unknown comparison: Raloxifene is a medication that has effects similar to estrogen on the bone. Strontium ranelate is an organic form of the element strontium. It has effects on bone that are different than raloxifene. It is not approved for use in the us but is available in europe. There are no comparative studies between the two drugs. Both have different potential side effects. You need to talk to your doc. ...Read moreSee 1 more doctor answer
Is it normal to experience jaw pain as a side effect from taking the prescription drug evista (raloxifene) for osteoporosis?
Jaw pain: It is not normal to experience jaw pain on bisphosphonates (bone hardening drugs) and this can be an early warning side of a rare side effect, osteonecrosis of the jaw (ONJ). See your prescribing physician immediately and he/she may order a CT scan of your jaw. ...Read moreSee 2 more doctor answers
Bone density, risk?: The primary indications for Raloxifene are for bone strength/density which is assessed via a bone densitometry study. The other role is for breast cancer chemoprevention with requires risk assessment by one of several models such as the gail model. The risk level used in the primary trial was a 5 year risk of >1.67%. ...Read more
.?: I'm not sure what you are asking but I recommend you discuss this with your physician/oncologist. ...Read more
Most prefer surgery: Whatever your age, most men with gynecomastia prefer surgery, which is effective, definitive and easy. I'll trust this is not pseudogynecomastia and that your thyroid and liver are in good working order. Tamoxifen is acceptable if for some reason surgery isn't right foryou. ...Read moreSee 1 more doctor answer
Breast? Likely no: The primary trial of Raloxifene for breast chemoprevention was limited to 5 years of use to match the standard of 5 years of tamoxifen. Recent data suggest a benefit of 10y of tam over 5 years for treatment of invasive er+ breast cancer. However, the benefit of the extra five years is not seen until after year 10. That suggests that the benefit of that drug holds for 5 years after it is stopped. ...Read more
Menopause: Raoxifene's first role was as an "estrogen receptor modulator, " meaning that it slows estrogen down in some tissues (uterus, breast) and enhances it in others (bones). Doctors prescribed it to slow osteoporosis, and its breast cancer reducing properties were discovered serendipitously. ...Read more
Flushes, leg cramps: Raloxifene (evista) is used to prevent and treat osteoporosis. It also prevents breast cancer. Although most people do not experience significant side effects, hot flashes and leg cramps may occur. Evista (raloxifene) also slightly increases the risk of thromboembolism (blood clots in the legs or lungs). ...Read more