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Doctor insights on: Raloxifene Side Effects

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Does evista (raloxifene) have adverse side effects if a person takes it more than 5 years?

Does evista (raloxifene) have adverse side effects if a person takes it more than 5 years?

Perhaps: Evista (raloxifene) if taken to reduce breast cancer in post-menopausal women is usually taken just for 5 years but there is no limit number of years if taken for osteoporosis. There may be an increase risk of ovarian cancer the longer it is taken. Increased risk of stroke or blood clots is not necessarily related to duration of intake. ...Read more

Dr. Jacob Udell
139 Doctors shared insights

Raloxifene (Definition)

The medication is a selective estrogen receptor modulator (serm). The medication is used in menopausal patients to address the issue of osteoporosis or brittle bones. It also is used for invasive ...Read more


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Strontium ranelate, tamoxifen, raloxifene - are the side effects the same regarding dvt, heart attacks etc &which would offer more protection for bone?

Strontium ranelate, tamoxifen, raloxifene - are the side effects the same regarding dvt, heart attacks etc &which would offer more protection for bone?

Raloxifene: Of all the products you mentioned, Raloxifene has the most well established record and is fda approved to improve bone density. Unfortunately, its ability to do so appears weaker than bisphosphanate products, teriparitide (forteo) of prolia. The other products you mentioned are not fda approved bone building products. Strontium is not available in the us as an anti-osteoporotic agent. ...Read more

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Is evista (raloxifene) commonly used for osteoporosis, or are there dangerous side effects?

Is evista (raloxifene) commonly used for osteoporosis, or are there dangerous side effects?

Blood clotting: The most common is worsening of menopausal symptoms, but blood clots (particulary in the legs) are much more serious. Do not use if you're a smoker or have a problem with clotting. ...Read more

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Which is the safest osteoporosis treatment between raloxifene and strontium ranelate or are they equal in similar side effects?

Unknown comparison: Raloxifene is a medication that has effects similar to estrogen on the bone. Strontium ranelate is an organic form of the element strontium. It has effects on bone that are different than raloxifene. It is not approved for use in the us but is available in europe. There are no comparative studies between the two drugs. Both have different potential side effects. You need to talk to your doc. ...Read more

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Is it normal to experience jaw pain as a side effect from taking the prescription drug evista (raloxifene) for osteoporosis?

Is it normal to experience jaw pain as a side effect from taking the prescription drug evista (raloxifene) for osteoporosis?

Jaw pain: It is not normal to experience jaw pain on bisphosphonates (bone hardening drugs) and this can be an early warning side of a rare side effect, osteonecrosis of the jaw (ONJ). See your prescribing physician immediately and he/she may order a CT scan of your jaw. ...Read more

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What tests are required for taking raloxifene?

Bone density, risk?: The primary indications for Raloxifene are for bone strength/density which is assessed via a bone densitometry study. The other role is for breast cancer chemoprevention with requires risk assessment by one of several models such as the gail model. The risk level used in the primary trial was a 5 year risk of >1.67%. ...Read more

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Does raloxifene lower ldl?

Does raloxifene lower ldl?

Like estrogen: Raloxifene (evista), along with decreasing breast cancer risk and treating osteoporosis, appears to lower LDL by binding to estrogen receptors and effecting lower LDL similar to estrogen. ...Read more

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What's the cost of tamoxifen or raloxifene?

What's the cost of tamoxifen or raloxifene?

I know tamoxifen is: Very cheap; I do not know raloxifene's cost, but it is less likley to cause bony demineralization, but is not as "tested" as tamoxifen as an anti-estrogen. ...Read more

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Please describe the medication: evista (raloxifene)?

Please describe the medication: evista (raloxifene)?

Women's health: E vista (raloxifene) is a selective estrogen receptor modulator used for osteoporosis and breast cancer prevention. Http://en. Wikipedia. Org/wiki/raloxifene. ...Read more

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How does raloxifene help cholesterol; I heard it does?

Unknown: Raloxifene affects LDL and total cholesterol in a fashion similar to estrogen. Unlike estrogen HDL is unaffected. The precise mechanism is not known at this time. It is not related to sequestration and elminination of cholesterol in bile. ...Read more

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I stopped taking evista (raloxifene) after taking it for 10 years?

.?: I'm not sure what you are asking but I recommend you discuss this with your physician/oncologist. ...Read more

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Any advice? What tests are required before taking evista (raloxifene)?

Bone density test: It depends on why you are taking it. A baseline bone density test would be a good idea if you were postmenopausal or had some other reason for bone loss. I am guessing you are asking for someone who is postmenopausal. ...Read more

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If your gynemostia is idiopathic would taking tamoxifen or raloxifene be harmful?

If your gynemostia is idiopathic would taking tamoxifen or raloxifene be harmful?

Most prefer surgery: Whatever your age, most men with gynecomastia prefer surgery, which is effective, definitive and easy. I'll trust this is not pseudogynecomastia and that your thyroid and liver are in good working order. Tamoxifen is acceptable if for some reason surgery isn't right foryou. ...Read more

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I stopped taking evista (raloxifene) after taking it for 10 years. Any consequences?

Breast? Likely no: The primary trial of Raloxifene for breast chemoprevention was limited to 5 years of use to match the standard of 5 years of tamoxifen. Recent data suggest a benefit of 10y of tam over 5 years for treatment of invasive er+ breast cancer. However, the benefit of the extra five years is not seen until after year 10. That suggests that the benefit of that drug holds for 5 years after it is stopped. ...Read more

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What is raloxifene used for other than cancer?

What is raloxifene used for other than cancer?

Menopause: Raoxifene's first role was as an "estrogen receptor modulator, " meaning that it slows estrogen down in some tissues (uterus, breast) and enhances it in others (bones). Doctors prescribed it to slow osteoporosis, and its breast cancer reducing properties were discovered serendipitously. ...Read more

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Any adverse reactions to raloxifene?

Flushes, leg cramps: Raloxifene (evista) is used to prevent and treat osteoporosis. It also prevents breast cancer. Although most people do not experience significant side effects, hot flashes and leg cramps may occur. Evista (raloxifene) also slightly increases the risk of thromboembolism (blood clots in the legs or lungs). ...Read more

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What is raloxifene for?

Osteoporosis: Raloxifene (evista), along with decreasing breast cancer risk, is used to treat and prevent osteoporosis. ...Read more

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Please describe the medication: raloxifene?

Please describe the medication: raloxifene?

Raloxifene: The medication is a selective estrogen receptor modulator (serm). The medication is used in menopausal patients to address the issue of osteoporosis or brittle bones. It also is used for invasive breast cancer risk reduction. ...Read more

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Dr. Daniel Lebowitz
47 Doctors shared insights

Evista (Definition)

Evista is a metabolic agent which is a kind of ...Read more