Doctor insights on:
Raised B12 And Folate
Dx and treated B12 def with lvl of 78 five yrs ago, but now ferritin 13 (12-250ug/l) and folate (folic acid) 6.3 (4-20ug/l), should these levels b supplemented?
Iron: There is certainly no harm in supplementing your folate (folic acid) (must continue your b12!) but that level seems fine. Your ferritin level seems low and most likely indicates that there is not enough iron in your system. This too can lead to anemia. Iron supplements seem indicated. You should see your doctor to fully evaluated why your ferritin is low. ...Read more
Folic acid, AKA folate (folic acid) (vit B9), is recommended for all women wanting to get pregnant -- 0.4mg (400mcg) daily, which is important for preventing birth defects like spina bifida. Women w/ a hx these disorders should take 10x that amt daily -- 4mg (4000mcg) through the 3rd month of pregnancy. It won't affect fertility, chances of conception/twins, or periods. ...Read more
28 yr down syndrome female wbc 2.8 vitamin d 9 b12 208 hypothyroid under control on vitamin d and b12 rest of cbe and platlets normal ?
Leukopenia: Low white cell count with normal red cell series and platelets has several causes like autoimmune disease,aleukemic leukemia,medication induced,viral illness, but may also have no identifiable cause. 2800 is quite low and the differential white cell count becomes important to know. A hematologist is best qualified to evaluate the situation. ...Read more
B12 deficiency. I take b12 supplements but my MCV is always on high end of normal. I also take folic acid. B12 blood tests 600. ?
B12: How long have you had B12? other medications ? Liver issues? Thyroid? Tested MTHFR gene ,methylmalonic acid /homocysteine/or for pernicious anemia- intrinsic factor antibodies or parietal cell antibodies ? GERD/ Crohns/bacterial overgrowth/ Whipple's as they may affect absorption. 600 appears adequate ,but body may have utilization dysfunction/variant. f/u/w/doc ...Read more
Previous ida. Now high B12 and folate (folic acid) levels. Ferritin result is not back. Significant hair loss and sob? Could high folate (folic acid) mask B12 deficiency? Thx
Masks anemia only: High folate (folic acid) can mask megaloblastic anemia caused by B12 deficiency but does not affect B12 levels. The high B12 levels you have are proof that you don't have B12 deficiency. I don't know what ida is. Hair loss ; sob can have many causes. It sounds like you are being evaluated for possible causes. ...Read more
Folic acid -24.6, serum B12 - 600, high folic acid may mask B12 def, what does that mean? is serum B12 falsly high? what other tests for B12 def?
No: See answer to another of your questions on the same topic. ...Read more
Red cells large 5 yrs after correction of B12 def. With high erythroproiten level. Further testing?
Yes: There are many things that can cause elevated red blood cell size-besides vit B12 deficiency. To name some of them will include thyroid problems, other deficiency, bone marrow failure, liver problems, drugs related, breaking down of red blood cells etc. Yes, you should have work-up done. Please go to see your doctor and get yourself checked. ...Read moreSee 1 more doctor answer
B12 deficient common: Being vegetarian may reduce risk of folate (folic acid) deficiency, as the best sources of folate (folic acid) are dark leafy greens, lentils, beans, broccoli & asparagus.However, fruits & vegies generally don't contain b12, so vegetarians are at risk of B12 deficiency.Eggs and dairy products do have b12, but even vegetarians who eat those average less than half the rda of b12. B12 supplements are thus advised. See comment:. ...Read more
Probably: Need injections to catch up.Get a more detailed answer ›
My mom is 66 and has elevated homocysteine levels. B12 and folate (folic acid) are normal. On BP meds but systolic still high. Any thoughts or suggestions?
MTHFR: There are several causes for high homocysteine levels but the most common is the mthfr gene mutation. The mutation affects the metabolism of folic acid, which utilizes b12. Often, blood levels look normal but the body is actually not able to process the vitamins so the homocysteine remains elevated. Also, the B12 and folate might look "normal" but might not be optimal. More tests are needed. ...Read more
My recent lab tests came back with Iron level of 30, transferrin of 20%, low vitamin D, high B12 and high folate. Is this cause for concern?
Please what's the difference between pernicious anemia and vitamin B12 deficiency.my iron levels are perfect.I'm getting injections for vitamin b12.
Intrinsic factor: Vitamin B12 is present in meat and animal protein foods. Absorption of B12 occurs in the intestine (ileum) and requires intrinsic factor (IF), made by stomach cells. In pernicious anemia, IF production is deficient, and results in anemia, a reduction in hemoglobin/hematocrit. One can be vitamin B12 deficient without becoming anemic and/or without having deficient IF. Best wishes:) ...Read more
28 yr down syndrome wbc 2.8 diff, platlets norm vit b12= 220 vit d 9 put on vit d and b12 is this tx okay?
Neutropenia, low : white cell count, occurs 1/3rd of people with DS;macrocytosis, large red blood cells persist in 2/3rds & are not usually related to B 12 deficiency. A borderline level of B12 warrants obtaining levels of folic acid, methylmalonic acid, homocysteine, Free T4 & Ultrasensitive TSH. Low Vitamin D levels are associated with obesity, common in DS. Further evaluation by a hematologist is warranted. ...Read more