Doctor insights on:
I have been taking carbamazepine 200mg for 2 weeks and I do not have epilepsy. I am looking to come off. Can I quit cold turkey or should I titrate?
An old drug: Tegretol has been on the market for many years. It was one of the first antiseizure medications and is still prescribed pretty frequently. It is not without a slight risk for problems, however. Your doctor checks blood counts looking for signs of anemia or bone marrow problems, liver function tests to make sure the liver isn't affected, and a tegretol level to see how much is in your system. ...Read more
Information below: The absorption of carbamazepine in man is relatively slow. When taken in a single oral dose, the carbamazepine tablets and chewable tablets yield peak plasma concentrations of unchanged carbamazepine within 4 to 24 hours. With respect to the quantity of carbamazepine absorbed, there is no clinically relevant difference between the various dosage forms. However, carbamazepine suspension is absorbed somewhat faster than the tablet; peak plasma levels are reached within 2 hours. Following b.i.d. dosage regimens, higher peak levels and lower trough levels are obtained with the suspension than with the tablets. Steady-state plasma levels are comparable for carbamazepine suspension given t.i.d. and carbamazepine tablets given b.i.d., when administered at the same total daily dose. ...Read more
Tegretol XR: Start 100-200mg in two divided doses followed by a slow increase in dosage (every3-7days) until the effect is obtained, often 800-1200mg daily. However, this should only ever be under the supervision of a doctor. ...Read more