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Doctor insights on: Quitting Simvastatin

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I quit taking vytorin (ezetimibe and simvastatin) due too difficult he sleeping. I stopped it 8 days ago how long will it take for it to get out of my system so i can sleep again?

I quit taking vytorin (ezetimibe and simvastatin) due too difficult he sleeping. I stopped it 8 days ago how long will it take for it to get out of my system so i can sleep again?

Few days, ? Response: Vytorin (ezetimibe and simvastatin) has 2 active ingredients. Assuming normal heart, liver & kidney function, the elimination half-life (time for blood concentrations to halve) for Simvastatin is <2 hrs & ezetimibe ~22 hrs. Generally, about 5 half-lives (i.e. 5 x 0.5) is enough that little to no biologic activity persists. However, sleepiness was not a side effect found in clinical trials: consider other possible causes. ...Read more

Dr. Blase Carabello
400 doctors shared insights

Simvastatin (Definition)

Treats high cholesterol and triglyceride levels in the blood. Lowers risk of heart attack, stroke, and certain blood vessel problems in people with certain risk factors. This medicine is an hmg-coa reductase inhibitor, ...Read more


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When does someone get simvastatin?

When does someone get simvastatin?

When LDL is high: Simvastatin is a statin drug good to lower LDL (bad) cholesterol. It is usually given when diet and exercise fail to reduce cholesterol to guideline levels. It is also started when pts have known coronary or cerebral artery disease and the level needs to be controlled faster. ...Read more

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Should you take simvastatin at night?

Should you take simvastatin at night?

Yes: If possible. Cholesterol production peaks in the evening/at night, so it's believed that taking statins at that time helps maximize their effectiveness. ...Read more

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Simvastatin, one every other day okay?

simvastatin: The data for Simvastatin effective use are based on once a day. It may work every other day but no good data to support that. ...Read more

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Who should not use Zocor (simvastatin)?

Who should not use Zocor (simvastatin)?

Zocor (simvastatin): simvastatin/Zocor See: http://www.rxlist.com/zocor-drug/overdosage-contraindications.htm

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Could simvastatin make you gain weight?

Could simvastatin make you gain weight?

Per Drugs.Com: Simvastatin has potential side effects to include: Increased hunger, loss of appetite and weight loss. ...Read more

Dr. Sanjiv Kaul
205 doctors shared insights

Zocor (Definition)

Zocor is a HMG-CoA enzyme blocker which is a kind of cholesterol/lipid ...Read more