Doctor insights on:
I quit taking vytorin (ezetimibe and simvastatin) due too difficult he sleeping. I stopped it 8 days ago how long will it take for it to get out of my system so i can sleep again?
Few days, ? Response: Vytorin (ezetimibe and simvastatin) has 2 active ingredients. Assuming normal heart, liver & kidney function, the elimination half-life (time for blood concentrations to halve) for Simvastatin is <2 hrs & ezetimibe ~22 hrs. Generally, about 5 half-lives (i.e. 5 x 0.5) is enough that little to no biologic activity persists. However, sleepiness was not a side effect found in clinical trials: consider other possible causes. ...Read more
When LDL is high: Simvastatin is a statin drug good to lower LDL (bad) cholesterol. It is usually given when diet and exercise fail to reduce cholesterol to guideline levels. It is also started when pts have known coronary or cerebral artery disease and the level needs to be controlled faster. ...Read more