Doctor insights on:
Usually effective: Like all medications Provigil (modafinil) works better for some people than it does for others, and there are some people for whom it may not work at all. However, in my experience, it has been a highly effective medication for most people with excessive fatigue. It is indicated for excessive sleepiness caused by sleep apnea, narcolepsy, and shift work, but it is used off label in many ways. ...Read moreSee 1 more doctor answer
It's expensive: But will be generic soon. It is known generically as modafanil and is made by several companies, especially india. Why sun pharmaceuticals can sell modalert 200 mg for 1.59$ and Provigil is $14 is beyond me. Teva has bought cephalon and owns the next 2 companies i line who could make generics. In 2-3 years the price will come down and i'll bet use increases. It's a good medicine. ...Read moreSee 1 more doctor answer
Wakes up the brain: Modafanil (provigil) appears to increase the activity of the brain wakefulness centers without causing a significant increase in Dopamine or norepinephrine release (unlike the stimulant medications). This is why its abuse potential is lower than other medications that improve alertness. ...Read moreSee 4 more doctor answers
About an hour: After oral ingestion, should start being absorbed in about 45-60 min, with blood levels stabilizing within 90-120 hrs maximum. If an effect is not experienced by then may need to ramp up dosage, but usually 200 mg daily should work. However, if generic, may not get absorbed as well. And some need Nuvigil instead. ...Read more
About a day: The half life (time it requires for 50% of the medication to be eliminated from the body) is roughly 15 hours. The clinical effects of the medication are typically gone in under a day. The medication is almost completely cleared from your system within a few days. ...Read more
Is there a generic for provigil available in the united states yet? I've tried to find an answer, but have found mixed results.
I take 200 mg of provigil daily to treat narcepsy. After 7 years it is not keeping me awake anymore. Could I have dveloped an immunity to the drug?
Narcolepsy: Check with your physician for the possibility that you may have developed other conditions like hypothyroidism, obstructive sleep apnea, depression, organic brain disorders, lack of exercise or poor sleep habits. He may need to reevaluate your medications. Hope you feel better soon. ...Read moreSee 1 more doctor answer
Depends: There are numerous studies showing some benefit from Provigil for treatment of adhd, but the fda raised concerns over possible side effects at doses necessary for adhd effectiveness, which is higher than for excessive sleepiness. However, a number of psychiatrists have used it off-label in that way. ...Read moreSee 4 more doctor answers
Wakefulness: Modafinil is classified as a somnolytic, and promotes alertness and wakefulness through selective activation of wake and sleep centers in the central nervous system. The fda has approved its use in nacrolepsy, adjunctive treatment of excessive daytime sleepiness associated with obstructive sleep apnea, and shift-work sleep disorder. Off-label, it's used for adhd and adjectively for depression. ...Read moreSee 1 more doctor answer
Been on provigil for narcolepsy for 10yrs are then any studies for possible problems with long term use?
Unlikely: Most patients on Provigil do very well without any long-term problems. Always prudent to periodically check liver fnctns and blood count just in case, but unlikely any issues. Also, positive is fact that tolerance with Provigil is rather uncommon, so doseage can stay stable. ...Read moreSee 1 more doctor answer
I just started taking a drug called provigil, but i can't afford it. Can you tell me how to apply for hardship case?
Provigil: There is a patient assistance program for provigil. Your physician can help you apply for this if you go to this link: http://www.Provigil.Com/prescription_assistance_patient.Aspx good luck to you. ...Read more
I'm concerned. My sister is consuming daily 200 mg of provigil daily during his exams(over 1 month). What are the riskiest side effects?
Safe: Provigil is a medication to decrease excessice daytime sleepiness. It is a pro-histamine and increases wakefulness and can sharpen awareness. It can help ms fatigue and other conditions. It is usually not given for attentention. It seems that your sister is taking it as a stimulant. Short term there are few risks. ...Read moreSee 2 more doctor answers
Opinions on provigil? Don't look into the question. Just throw your 2 cents in on your thoughts, feelings, what you actually know about it, etc.
Provigil: Provigil has fda indications for narcolepsy, a chronic brain disorder involving poor control of sleep-wake cycles. There are cataplexy, excessive daytime sleepiness, sleep paralysis, and hallucinations with falling asleep and/or waking up. Provigil is useful when prescribed for this. Your additional clinical information mentions that you're already using a stimulant (adderall) without having add. ...Read moreSee 1 more doctor answer