Doctor insights on:
I take gabapentin for my fibromyalgia, but the helpful effects seemed to have worn off. I'm in excruciating, constant pain. Any suggestions?
I have been on Naproxen 500gm 2x per Day for a very long time. I also take lithium, gabapentin, and villadozone. What is the half life if I quit now?
I have been on Neurontin (gabapentin) for 19 months and started having depression. The skin on my back burns. I was prescribed it for anxiety. Should I quit it?
Gabapentin: Gabapentin is a neuromodulating drug that works by blocking an excitatory neurotransmitter in your body called glutamate. By decreasing the amount of general excitation of pathologic nerves (from diabetes, sciatica, carpal tunnel syndrome, etc), Gabapentin helps to reduce the pain from those conditions. 800 refers to the dose, though is too high to start on. Side effects include sleepiness. ...Read moreSee 2 more doctor answers
Many uses: Gabapentin aka Neurontin (gabapentin) is considered an anti epileptic, but is rarely used for epilepsy except as an adjunct to other medications. It is more commonly used for neuropathic pain or as a muscle relaxant. It's exact mechanism of action is unknown except that it blocks voltage-dependent calcium channels and modulates excitatory neurotransmitter release ...Read more
Good Question: Most substances to be addictive must be shown to be associated with a Dopamine release in the brain's reward centers. I'm not aware of evidence for that with Gabapentin but nonetheless it is for some a potent anti-anxiety agent, so it doesn't surprise me that addictive like patterns can emerge. If that's the case it is time to look for other ways to safely and effectively address the anxiety. ...Read more
Gabapentin: Gabapentin is used to treat partial seizures, pain related to post herpetic neuralgia as well as neuropathic pain. While it does modulate the activity of the major inhibitory neurotransmitter in the brain, gaba, it's mechanism of action is significantly different from that of a benzodiazepine or barbiturate. As a result does not result in physiologic dependence. ...Read moreSee 1 more doctor answer
Relaxant & analgesic: Gabapentin (marketed as neurontin) is a drug used for the treatment of epilepsy (anticonvulsant), chronic nerve-related pain (analgesic), and conditions like fibromyalgia. Its side effects include dizziness, fatigue, weight gain, drowsiness, & swelling of extremities. A structurally related compound is gaba, a supplement that has a calming, relaxing, & anti-anxiety effect on the body. ...Read moreSee 1 more doctor answer
Gabapentin problem: In 2008, the us food and drug administration mandated warning labeling for anticonvulsant medications regarding the increased risk of suicidal thoughts and behaviors. Patorno et al 2010 found gabapentin, lamotrigine, oxcarbazepine, and tiagabine, compared with the use of topiramate, may be associated with an increased risk of suicidal acts or violent deaths. Gabapentin by itself is beneficial. ...Read moreSee 1 more doctor answer
Yes, separately: My main concern is the possibility that the magnesium that is an ingredient in the airborne could reduce the availability of the gabapentin. Some sources talk of twenty percent reduction, I am not sure if that would translate into anything that would be noticeable to you. You would do best to to space it out and take the Gabapentin at a completely different time 2 hours or more apart. Stay safe! ...Read more