Doctor insights on:
Multiple effects: Amiodarone is primarily a class iii anti-arrhythmic agent. It prolongs the depolarization phase of cardiac muscle--the muscle takes longer to reset after contraction, slowing down the heart rate. Amiodarone also acts on sodium & potassium channels to delay conduction of the action potential through the sa & av nodes. ...Read more
Slow Down There: Antiarrhythmics are, as a rule, complicated drugs with a lot of side effects and a ton of potential contraindications. They are not easily interchangeable. At the very least a cardiologist and better still an electrophysiologist should help you decide which are eligible for you specifically. That said, dofetilide, sotalol, flecainide, propafenone, verapamil and dronedarone are some freq. Choices. ...Read more
Anti-arrthymic med: Amiodarone is a medication used to suppress extra heartbeats and maintain a normal regular heart rhythm .It is used most frequently in a low dose to prevent episodes of atrial fibrillation, a heart rhythm that can lead to strokes. It can also be used in higher doses to prevent ventricular extra beats.Amiodarone can have many potential side effects and must be used by an experienced cardiologist. ...Read moreSee 2 more doctor answers
It is an : Effective drug in the right patient. It can be useful to treat atrial and ventricular arrythmias. It is no without side effects and patients need to be closely followed by the prescribing doctor. ...Read more
All the same: All drugs in this group called class lll antiarhytmics including amiodarone have potentially serious side effects that can be life threatening. Amiodarone compared to others have in addition side effects that affect the thyroid ,lungs, liver etc. It is best to discuss thoroughly the other drugs (sotalol,Ibutilide,etc) with cardiologist experienced in using these drugs ...Read more
Many...: These generally break down into two categories. There are rare, but very severe issues including pulmonary fibrosis, liver dysfunction, and thyroid dysfunction. There are also GI side effects (nausea) skin changes (over decades, the skin turns a bluish grey) and more mild thyroid issues which may require thyroid supplementation or other such treatment. ...Read more
Amiodarone : halftime around a month. Usually 5 halftimes to eliminate 90% of a drug. Effects of drug usually disappear when level of drug is low enough ...Read more
Either: Does not truly matter so long as it is about same time each day. ...Read more
I started amiodarone on March 28 and stopped April 30. What's the half life for that small amount of time?
Really really long: amiodarone stays in the system for a very long time. the last bit of it decreases by half approximately every TWO MONTHS http://www.ncbi.nlm.nih.gov/pubmed/10872646 about 20% incidence of adverse events BUT, the more serious adverse events basically only occur with being on the drug for a much longer time. ...Read more
If you take 200MG of Amiodarone for 3 months and 100MG for the next 3 months when will it be out of your system?
Weeks-months: Amiodarone is one of those antiarrhyhtmic drugs with a long 1/2 life (average of 50 days, range 30-100 days). So depending on whether you were front loaded or not, that you have been on it for 6 months, it is likely going to take a good 3 months for all drug to be out of your system. It is hard to predict reliably, because of its accumulation in fat tissue, etc.... ...Read more