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Doctor insights on: Pyruvic Acid Pyruvate

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What happens to pyruvic acid b4 if you take too much?

What happens to pyruvic acid b4 if you take too much?

Pyruvic acid (B4): Pyruvic acid. Pyruvic acid is used by weightlifters and body builders to help produce cellular energy during exercise, which can increase power and strength during resistance training. The use of pyruvic acid and calcium pyruvate may cause side effects, such as gastrointestinal distress, kidney stress, increased cholesterol, and hypercalcemia. ...Read more

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Pyruvic Acid is low (lactate normal). What conditions are this associated with?

Pyruvic Acid is low (lactate normal). What conditions are this associated with?

Normal : lactic acid is normal under normal physiological conditions. It is elevated when tissues are not getting enough oxygen, when the body is poisoned by certain infections, or poisoning by certain chemicals. ...Read more

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Should I take pyruvic acid suplements on a diet?

Should I take pyruvic acid suplements on a diet?

Forget it: You do not need to complicate your life. Eat simple, healthy foods and exercise daily. Polant based foods are much healthier than animal based foods. Eat ample amount of veggies and fruits dauily and do not consume high sugar and high fat items. Get a good dose of proteins from eggs, nuts and soy products. If you can stick with these recommendations you will look good and feel great as a result. ...Read more

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Low pyruvic acid mg/dl, low pyruvic acid blood and low lactate plasma? What does this mean? Any one have any clue?

Low pyruvic acid mg/dl, low pyruvic acid blood and low lactate plasma? What does this mean? Any one have any clue?

Yes: It means you do not have an inherited disorder of metabolism such as a mitochondrial disorder. Not quite sure why you had it checked, unless you have trouble with waking or balance, seizures, or loss of sensation. ...Read more

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Is there a chance that pyruvic acid can treat a uti?

Is there a chance that pyruvic acid can treat a uti?

Probably not: It is not an antibiotic. Is used for treatment of acne to help skin peel & believe is being studied for its use intreatment of cancer. But do not know of any reports in its' use for utis. We know that antibiotics almost always work so why consider something like pyruvic acid? ...Read more

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My lactic acid and pyruvic acid are in the normal range (1.8 and 0.046 respectively), but is my L:P ratio elevated?

My lactic acid and pyruvic acid  are in the normal range (1.8 and 0.046 respectively), but is my L:P ratio elevated?

In the setting of?: L:P ratio > 30 suggests inherited disorders of the respiratory chain complex or tricarboxylic acid cycle disorders. An elevated lactate and a L:P ratio less < 25 suggests a defect in pyruvate metabolism. Are you being worked up for congenital lactic acidosis? ...Read more

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What happens to pyruvate and glutamate when fasting?

What happens to pyruvate and glutamate when fasting?

You've pushed me---: I've been avoiding this question (as my colleagues have as well). I never was a fan of biochem in college or medical school. But I still have&refer to my Lubert Stryer from time to time...not the most recent edition you understand but mine is SPECIAL. Anyways, I'm still going through the chapter on amino metabolism which partially explains this so stay tuned. I promise to answer this shortly! ...Read more

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Whats pyruvate dehydrogenase complex?

Whats pyruvate dehydrogenase complex?

Enzymes: Pyruvate dehydrogenase complex is a complex of three enzymes in the mitichondria that change the Amino Acid pyruvate into the molecule acetyl-coa by a process called pyruvate decarboxylation. Acetyl-coa is used in the citric acid cycle to make energy for cells the complex links the metabolic pathway that breaks down glucose (elemental sugar) to the citric acid cycle. ...Read more

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Could you die from pyruvate dehydrogenase complex?

Could you die from pyruvate dehydrogenase complex?

Odd question!: Hi. Pyruvate dehydrogenase is a vital step in intermediary metabolism! Do you mean could you die if one of the genes in the pyruvate dehydrogenase complex produced a non-functional enzyme? Don't know about heterozygotes; they might be OK. Homozygous mutant would be an embryonic lethal, I am sure. I'm really curious what led you to ask that bizarre question! ...Read more

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Can calcium pyruvate lead to hypercalcemia?

Can calcium pyruvate lead to hypercalcemia?

No: Any calcium product taken in large amounts can increase calcium levels in susceptible people. Pyruvate is the major component of calcium pyruvate. Large amounts of the supplement is likely to cause nausea instead of high calcium. ...Read more

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What is the difference between calcium citrate vs calcium pyruvate?

What is the difference between calcium citrate vs calcium pyruvate?

Depends on use: Calcium pyruvate is currently being pushed as a supplement for weight loss, but without proof. It has not been evaluated for treatment or prevention of osteoporosis and is considerably more expensive than calcium citrate. ...Read more

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Can you tell me why the following symptoms occur in pyruvate dehydrogenase defficiency?

Can you tell me why the following symptoms occur in pyruvate dehydrogenase defficiency?

Due to lactic acid: Pyruvate dehydrogenase deficiency is characterized by the buildup of a chemical called lactic acid in the body Too much lactic acid can cause nausea, vomiting, heart and breathing problems. Acids in the blood interfere with the normal function of the body and that causes the symptoms Here is a helpful link http://ghr.nlm.nih.gov/condition/pyruvate-dehydrogenase-deficiency ...Read more

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What causes pyruvate dehydrogenase complex deficiency?

What causes pyruvate dehydrogenase complex deficiency?

Mitochondrial diseas: A very rare genetic disorder which leads to neurodegeneration. Presenting in infancy or later childhood, the earlier presentation is usually more severe. Those who develop symtpoms later in childhood may survive into adulthood. ...Read more

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What's pyruvate dehydrogenase deficiency?

Pyruvate: Please go online to Wikipedia and look for pyruvate dehydrogenase deficiency. Not easy reading but important. If that is what you have it can be controlled to some extent. Take your time reading the article(s) and then discuss with your doctor. ...Read more

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What is a pyruvate dehydrogenase complex deficiency (pdcd)?

What is a pyruvate dehydrogenase complex deficiency (pdcd)?

Pyruvate ....: Much to much to get in short response. Please go on-line to "emedicine.medscape.com" and you will find a lot of important information. You will find other similar comments on the web as well. If you don't have computer access please visit your local library and they will guide you to the right articles. ...Read more

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Is pyruvate dehydrogenase deficiency heritable?

Is pyruvate dehydrogenase deficiency heritable?

Yes.: In the most common situation it is inherited in an x-linked pattern, affecting hemizygous males (with one x chromosome) and heterozygous females (two x chromosomes, one with mutation). Less commonly it is inherited in an autosomal recessive pattern, in which a mutation must be provided by both the mother and the father of the affected person. ...Read more

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How can I test if I have pyruvate dehydrogenase deficiency?

How can I test if I have pyruvate dehydrogenase deficiency?

Call Stanford U: This disorder has metabolic and neurological manifestations with a wide range of severity, caused by mutations in an enzyme complex with multiple subunits. Testing is available at stanford university school of medicine in palo alto, ca. ...Read more

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Who suffers from pyruvate dehydrogenase deficiency (age, sex, race, etc)?

Who suffers from pyruvate dehydrogenase deficiency (age, sex, race, etc)?

Suffers: The best way for you to begin to understand this is to go online and look up "Wikipedia" related to this topic. Not always easy to follow but worthwhile. Another option would be to look up the National Institute of Health (NIH). They may put things in an easier ;language. ...Read more