Doctor insights on:
Pyridostigmine Bromide Medication
I have been diagnosed with maysethenia gravis I'm now on mestinon (pyridostigmine) I just want to know is there any better drug ?
Comments: Mestinon (pyridostigmine) is a good starter drug, as it can specifically benefit the neuromuscular junctional issues chemically, but may not be the best long-term solution. A thymectomy, and steroids are other alternatives to deal with the process, but you might find additional support from a neurologist who specializes in muscle disease. ...Read more
Side Effects?: If you are asking about side effects, the following are common adverse effects: loose stools/diarrhea, abdominal cramps, flatulence, heartburn, dizziness, sweating, excessive salivation, runny nose, muscle cramps, nausea/vomiting, increase urination, increase tearing, blurred vision, numbness in the skin, tiredness, and rash. There are other side effects. I hope this helps. ...Read more
Mestinon (pyridostigmine): In the Timespan Tablet form, it is equivalent to 60mg. of the Conventional Tablet form. ...Read more
Many: The serious reactions include arrhythmias, hypotension, syncope, bronchospasm, respiratory arrest, pulmonary edema, cardiac arrest, av block, bradycardia, paralysis, seizures, the common reactions include diarrhea, abdominal cramps, dyspepsia, headache, dizziness, hypersalivation, runny nose, muscle cramps, nausea/vomiting, blurred vision, fatigue, urinary frequency and others. ...Read more
Mestinon (pyridostigmine): If your doctor advised it.Get a more detailed answer ›
No one best medicine: Prednisone is the drug most commonly used to treat pemphigus. Other immunosuppressive agents are used either with or instead of Prednisone depending upon the individual's response & tolerance. All of these medications have potentially significant adverse effects so management by an expert in this disease and in using these drugs is vitally important. What's best for one is not best for another. ...Read more
What is the best medicine to treat pemphigus. I have heard about mestinon (pyridostigmine) working?
Pemphigus: Phemphigus vulgaris is a potentially fatal autoimmune mucocutaneous blistering disease. Conventional therapy consists of high-dose corticosteroids, imminosuppressove agents, and intravenous immune globulin. Studies show that the biologic Rituximab and intravenous Immune Globulin is very effective with refractory pemphigus vulgaris. Mestinon (pyridostigmine) is not as effective as rituximab. ...Read more
Mestinon (pyridostigmine) for Myasthenia, why does it seem like I feel weaker & etc AFTER taking it? Yet I'm afraid NOt to take it and get weaker!! what do u think?
Can rns give false negative result? Trying to get diagnosis. 1st rns showed 12.4% decrement. Trial of mestinon (pyridostigmine) helped breathing. Second rns normal? Musk and 3 achr ab normal. Now to 4th neuro in 1 yr.
Not sure. Describe a: Describe all your symptoms in detail.Get a more detailed answer ›
Activate muscle: Myasthenia disrupts the connection between nerve and muscle by reducing the number of receptors for a transmitter called acetylcholine. Mestinon (pyridostigmine) prevents acetylcholine from being broken down in the body, giving it more time to diffuse along the muscle and activate the remaining receptors. The net result is to restore effective transmission between nerve and muscle. ...Read moreSee 1 more doctor answer
Pyridostigmine: Absolutely.Get a more detailed answer ›
No: Not ever such a side effect. Do not worry! ...Read more
Not long ago diagnosed with myasthenia gravis and about to start mestinon (pyridostigmine). please help!?
Recently diagnosed with myasthenia gravis and about to start mestinon (pyridostigmine). What do I need to know?
Symptom treatment: While myasthenia reduces the effectiveness of muscle activation, Mestinon (pyridostigmine) works to increase it. It works well and starts working quickly, but does not change the course of the underlying disease- typically an immune modifying drug is used in conjunction with it to prevent disease progression. Typical side effects include diarrhea, abdominal cramping, and muscle twitches. ...Read moreSee 1 more doctor answer
Recently diagnosed with myasthenia gravis and about to start mestinon (pyridostigmine). Is it a powerful medicine?
I started mestinon (pyridostigmine) 5 days ago. 30mg tid. An hour after taking it, i get nervous, almost an anxiety feeling in my chest. Could this be a side effect?
My mom is suffering mysthania gravis from 5 years.She was taking mestinon (pyridostigmine).But from few days the mestinon (pyridostigmine) is not working well.So what she will do?
Needs re-evaluated : Mild myesthenia is treated symptomatically with mestinon, but most will eventually have to be treated by treating the actual disease with immune therapy, such as prednisone, ivig, cellcept (mycophenolate mofetil). These are drugs that actually block the abnormal antibodies from attacking were the nerve meet the muscles. ...Read more
How does ivig treatments help with mg? I am already on mestinon (pyridostigmine) and predisone with not much change.
Can stabilize: On occasion, ivig can interrupt a period of poor responsivity to your current meds. Some pts improve after 2 or 3 ivig infusions, and stabilize. Ivig contains many immune chemicals, and since myasthenia is a problem with the neuromuscular junction, the autoimmune attack can be quelled when a relapse occurs. Unlikely that you will need this approach permanently. ...Read more
Heart dr put me on Pyridostigmine and family dr told me to stop taking this of side effects heart Dr told me that will help me not to pass out?
Need to get: the two of them to talk to eachother. This happens every now and then. A simple phone call usually gets everyone on the same page and is appreciated by all. Best of health to you. ...Read more
My son is 6 and has Myasthenia. He is on mestinon (pyridostigmine). When do I know he does not need it everyday? Also what is the best ways to talk to him about it?
Meds are life-long: With myasthenia gravis, treatment is life-long. Do not change his dosage without clearing it with his doctor. At his age, the best way to discuss it with him is that he has a health condition that needs treatment every day. Explain to him that the symptoms he's had are from this condition. At 6 years old, he may not understand more detailed information than this. ...Read more
Moves things quicker: Because of how it works (enhances acetylcholine effect on gut) it can causes nausea/vomitting, increases peristalsis (moves bowel/gut/stomache quicker), salivation, urination frequency, as well as causing slow of heart rate and low blood pressure etc...Its only medical uses are for myasthenia gravis and as an antidote for some anesthetic agent. If u have much trouble, consult your doc. Good luck. ...Read more
NO, NOT AT ALL: Mestinon (pyridostigmine) enhances neuromuscular junctional efficiency by enhancing acetylcholine persistence, but is NOT an immune agent like a steroid. The standard testing for myasthenia gravis looks at antibody reactions, and would be positive or negative irregardless of use of Mestinon (pyridostigmine). ...Read more
Synaptic cleft: Pyridostigmine inhibits acetylcholinesterase in the synaptic cleft by competing with acetylcholine for attachment to acetylcholinesterase, thus slowing down the hydrolysis of acetylcholine, and thereby increases efficiency of cholinergic transmission in the neuromuscular junction and prolonges the effects of acetylcholine, what ultimately improves the strength of the muscle. ...Read more
Are there any new treatments for myasthenia gravis rather than the traditional cortisone and mestinon (pyridostigmine) or thymectomy?
Not really: Those are the tested ones.Get a more detailed answer ›
I would like to ask some medical advise since i don't have my menstrual period since november 2012 up to present, I have mg & taking mestinon (pyridostigmine)?
My left eye droops, and diagnosed as myasthenia gravis, but still droops on mestinon (pyridostigmine)?
Possible: First thing we need to know, how certain is the diagnosis? Was it established by blood tests, tensilon test, biopsy? If diagnosis is assuredly myesthenia gravis (mg), it is still possible for the ocular symptoms (droopy lid, double vision) to fail to respond to mestinon (pyridostigmine). See a specialist eye md (neuro-ophthalmologist) to decide if a higher dose of mestinon (pyridostigmine), steroids, or thymus surgery may help. ...Read more
My left eyes droop and was diagnosed as myesthenia graves. How long til mestinon (pyridostigmine) fixes the droop?
Not sure: Weeks or months, i think. Why not ask the doctor who prescribed it? ...Read more
My husband is taking mestinon, (pyridostigmine) methotrexate, and prednisone for myasthenia gravis. Are all 3 needed?
Quite possibly: About 1/3 can see spontaneous remission, 1/3 stabilize on chronic medications, and 1/3 have progressive difficulties. In appropriate candidates, minimally invasive thoracic surgery to remove thymus (thymectomy) can possibly cure or stabilize disease or decrease amount and/or types of meds. This link may help: http://goo.Gl/3xxmd. ...Read moreSee 1 more doctor answer
Diagnosed with M.G. by hosp. specialist by symptoms and Tensilon. Neg. EMG and bloods. Responded to Mestinon (pyridostigmine) and Prednisone. Can't get treatment.
There is more to: this than the tests that you mentioned. There a number of labs to consider and there is such a thing as seronegative MG (all labs negative and doubt from everybody). In the cases of seronegative MG, a single finger EMG helps confirm the diagnosis. Not all neurologists are trained in single fiber EMG and the ones that are typically did advanced EMG training. You may have to see a major center. ...Read more