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Doctor insights on: Pulmozyme

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Dr. Jeffrey Wint
6 Doctors shared insights

Pulmozyme (Overview)

Pulmozyme is a lung agent.


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Could pulmozyme (dornase alfa) use result in increased respiratory rate in non-cf patient with a tracheostomy?

Could pulmozyme (dornase alfa) use result in increased respiratory rate in non-cf patient with a tracheostomy?

Maybe: Side effects with Pulmozyme (dornase alfa) are various and can include irritation of the throat, nose and voice changes. It can also cause hoarseness. I use a fair amount in my patients and have not seen it increase respiratory rate. I guess if it was irritating the airway you could breath faster due to pain/discomfort. I don't think that increased resp rate is very common on this drug. ...Read more

Dr. Jeffrey Wint
6 Doctors shared insights

Pulmozyme (Overview)

Pulmozyme is a lung agent.


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Is it safe to take pulmozyme (dornase alfa) while pregnant or breastfeeding?

Is it safe to take pulmozyme (dornase alfa) while pregnant or breastfeeding?

Yes: Pulmozyme (dornase alfa) is a category b, deemed safe in pregnancy. Its safety in lactation is unreported, but should have minimal absorption, and I would consider the benefits vs risk for lactation on a case-by-case basis with my patients. ...Read more

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My sister makes herself throw up when she does her pulmozyme (dornase alfa). What can I do to help her?

My sister makes herself throw up when she does her pulmozyme (dornase alfa). What can I do to help her?

Mgt/CF: Some secretions can be swallowed and this can cause irritation of the stomach lining. She should speak with her PCP about the use of an antacid, following the Pulmozyme (dornase alfa) with nebulized saline to clear the secretions. Chest physiotherapy is an important part of her management. Does she wear a vest for CPT? A virtual consultation to review chest clearance and her medications can be booked online. ...Read more

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Is it safe to take pulmozyme (dornase alfa) while pregnant or breastfeeding?

Yes: Pulmozyme (dornase alfa) is a category b, deemed safe in pregnancy. Its safety in lactation is unreported, but should have minimal absorption, and I would consider the benefits vs risk for lactation on a case-by-case basis with my patients. ...Read more

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Could pulmozyme (dornase alfa) use result in increased respiratory rate in non-cf patient with a tracheostomy?

Maybe: Side effects with Pulmozyme (dornase alfa) are various and can include irritation of the throat, nose and voice changes. It can also cause hoarseness. I use a fair amount in my patients and have not seen it increase respiratory rate. I guess if it was irritating the airway you could breath faster due to pain/discomfort. I don't think that increased resp rate is very common on this drug. ...Read more

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How is dornase alfa helpful?

How is dornase alfa helpful?

Thinning mucus: Dornase alfa, called "pulmozyme", breaks down dna which is part of the material in thck chest mucus in patients with chronic lung disease such as cystic fibrosis. The medicine thins the mucus and makes it easier to cough out. It is used every day for months or years and gets into the lungs by inhaling the medicine in a mist. Treatments take 10-20 minutes. It's not used for colds or bronchitis. ...Read more

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Where should dornase alfa be stored?

Where should dornase alfa be stored?

In the refrigerator: There should be specific instructions when you get a new prescription as to where to store it (what temperature and for how long), and whether light damages it. There should also be an expiration date to tell you when it will no longer work if you keep it too long. Don't use it afterthat date. If you have questions, ask your pharmacist or go to the web site shown in the package insert. ...Read more

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Do you have idea about dornase alfa uses?

Thick chest mucus: Dornase alfa, called pulmozyme, (dornase alfa) is a medicine that makes lung mucus thinner and easier to cough up. It was developed for patients with cystic fibrosis and is used every day for months or years. It is not used for short-term colds or bronchitis. It gets into the lungs by breathing in a mist of the medicine from a nebulizer machine. Treatments usually take 10-20 minutes. ...Read more

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Is this free?

Is this free?

Yes, this is free if: If you did not ask for premium, paid services, then this HealthTap BASIC is free. Post your question in English, with good grammar and spelling, and one or more of the thousands of volunteer doctors will answer it. They might skip repetitive questions, or ones that have too many abbreviations, or are otherwise hard to understand. (HealthTap's premium services include virtual medicine appointments) ...Read more

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Are you free?

Are you free?

Yes, this is free if: If you do not request premium, paid services, then this HealthTap BASIC is free. Post your question in English, with good grammar and spelling, and one or more of the thousands of volunteer doctors will answer it. They might skip repetitive questions, or ones that have too many abbreviations, or are otherwise hard to understand. (HealthTap's premium services are personal consultations for a fee.) ...Read more

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Who gets omg?

Who gets omg?

Can you clarify?: Omg is a texting-age expression "oh my god" but used even by secularists to express amazement and dismay at once. It's no medical acronym that I recognize though there are some trashy websites preseting medical freaks as having "omg disease". To which disease are you referring? Someone on healthtap will be happy to answer. ...Read more

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Is this live?

Yes and No: There are doctors on here all of the time. Your questions may get answered immediately or be answered later, depending on the expertise of the doctors online at the time and whether they see your question. ...Read more

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I got pleups?

Do you mean polyps?: Regular follow up with primary care doctor! ...Read more

Dr. Andrew Seibert
4 Doctors shared insights

Dornase Alfa (Definition)

Dornase alfa ...Read more


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