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Doctor insights on: Ptu Medication

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What is the difference between ptu (propylthiouracil) and carbimazole? Is it possible to switch medication?

What is the difference between ptu (propylthiouracil) and carbimazole? Is it possible to switch medication?

Different: Carbimazole is converted to an anti=thyroid drug methimazole. Ptu (propylthiouracil) is a different anti-thyroid drug. Both are effective. Ptu (propylthiouracil) better, but not used as much since it can be associated with liver disease. Both have potential side effects. Talk w/your doctor. ...Read more

Dr. Kenneth Pennington
100 Doctors shared insights

Propylthiouracil (Definition)

Propythiouracil (PTU) can be used to control an overactive thyroid in the first trimester. PTU should be used with caution or avoided in the second and third trimester to ...Read more


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What are other medications for surgery other than carbimazole and propylthiouracil (ptu) and how effective are they?

What are other medications for surgery other than carbimazole and propylthiouracil (ptu) and how effective are they?

Don't understand: These drugs are used in the treatment of hypothyroidism. I am assuming you mean are they effective in the treatment of hyperthyroidism. That is something you need to discuss with you physician and endocrinologist. There are many causes of hyperthyroidism and it will depend on that. ...Read more

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My weight is raising after get medication for hyperthiroidism. Can I do exercise? I want standard weight now. Fyi doc here give me ptu (propylthiouracil) and propanol

Hyperthyroidism: Ptu (propylthiouracil) & propanolol are standard drugs used to treat an overactive thyroid (hyperthyroidism) which can lead to weight loss & fast heart rate. Propanolol is a beta blocker that keeps your heart from beating too fast. As ptu (propylthiouracil) normalizes an overactive thyroid, you stop losing weight & return to your normal weight by gaining it back. Healthy nutrition & regular exercise are always good. ...Read more

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Doc, my TBIL is high I take medication for my hyperthyroid and like atenolol and ptu (propylthiouracil). But my ALT and AST are normal.?

Doc, my TBIL is high I take medication for my hyperthyroid and like atenolol and ptu (propylthiouracil). But my ALT and AST are normal.?

Continue workup: In the absence of markers for hepatocellular injury, look at what bilirubin component is up, and determine whether this is new. Several percent of folks have Gilbert's which raises indirect and is harmless. If direct is up, consider a cholestatic response to some medication or if longstanding, a mild genetic glitch like Dubin-Johnson. Labs by themselves mean little. Best wishes. ...Read more

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Taken carbimazole and ptu (propylthiouracil) in the past for my thyroid, but they are not improving my condition, is there any other anti- thyroid drugs I can take?

Taken carbimazole and ptu (propylthiouracil) in the past for my thyroid, but they are not improving my condition, is there any other anti- thyroid drugs I can take?

Methimazole is also: Available and then there is radioiodine -- but any of the antithyroid drugs will work if taken at adequate doses for long enough to deplete stored up, previously manufactured, thyroid hormone. Check w/your doctor. ...Read more

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Pregnant taking ptu, (propylthiouracil) labetalol, methyldopa never done drugs in my life, I was tested positive for exstacy is that possible?

Pregnant taking ptu, (propylthiouracil) labetalol, methyldopa never done drugs in my life, I was tested positive for exstacy is that possible?

Yes, but: Ecstasy false positives have not been associated with those drugs, but otc drugs with decongestants, nose drops, nyquil, and weight loss drugs can. Do any of these ring a bell? ...Read more

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Tell me about ptu (propylthiouracil) effects/?

Liver toxicity: Fulminant hepatic failure is the most serious adverse effect (black warning exist for such risk). Other side effects include rash, joint pain and rarely bone marrow suppression. ...Read more

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For how long time did ptu (propylthiouracil) taken?

For how long time did ptu (propylthiouracil) taken?

PTU (propylthiouracil): Ptu (propylthiouracil) has an ongoing risk on bone marrow suppression and liver toxicity which is low but real. Some, but not all practitioners limit it's use to 1-2 years and then move to permanent management like radioactive iodine or surgery. ...Read more

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Can you have a bad reaction to propylthiouracil (ptu)?

Can you have a bad reaction to propylthiouracil (ptu)?

It's possible.: Ptu (propylthiouracil) can cause a skin reaction (hives, rarely), liver problems (more rare, but that's why it's use is severely restricted these days), and a drop in the white blood cell count (extremely rare). ...Read more

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Can you tell me about a bad reaction to propylthiouracil (ptu)?

Rash, liver, WBCs: Ptu (propylthiouracil) is a type of sulfa drug, so the most common side effect is a diffuse rash on the body. Occasionally it can affect the liver and cause inflammation. Periodic monitoring of liver tests is recommended while on the med. Rarely, it can lower one type of the white cells, increasing the risk of infection. We check the wbcs if one develops a fever or bad "cold" while on the med. ...Read more

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Is it possible for a person to have a bad reaction to propylthiouracil (ptu)?

Is it possible for a person to have a bad reaction to propylthiouracil (ptu)?

Absolutely: The fda has a black box warning on ptu (propylthiouracil) because it has been linked to liver failure in some. It can also cause failure of bone marrow to make certain type of immune cells. Rash and large joint inflammation are also known side effects. Methimazole is the anti-thyroid drug of choice in most. Although there are similar side effects between the two drugs, Methimazole may be safer for liver than ptu (propylthiouracil). ...Read more

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What's the maximum milligrams of ptu (propylthiouracil) a person can take daily?

Depends: Unless you are pregnant, we usually use Methimazole before ptu (propylthiouracil) because of the occasional liver problems with ptu (propylthiouracil). The dose has to be individual depending on the severity of the hyperthyroidism and the breakdown rate in your body. Some people have a very rapid breakdown and require very high doses to be controlled. If so, you need very close monitoring to use the lowest effective dose. ...Read more

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Should I be worried that I have gained 30 lbs in 6 months on ptu (propylthiouracil)?

Should I be worried that I have gained 30 lbs in 6 months on ptu (propylthiouracil)?

Had you lost weight?: Many hyperthyroid patients lose a lot of weight prior to diagnosis. Once treatment becomes effective, the weight comes back. Thyroid function tests should be monitored carefully as it's easy to become hypothyroid on ptu, (propylthiouracil) which would predispose to further weight gain. ...Read more

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How does ptu (propylthiouracil) beta blocker effect teen?

How does ptu (propylthiouracil) beta blocker effect teen?

Different drugs: Ptu (propylthiouracil) is a drug used to block the thyroid from making thyroid hormones in patients primarily with grave's disease. It has potential serious toxicities involving both liver and bone marrow. Methimazole may be safer, though also has toxicities. Blood work is monitored closely. Beta blockers are medications which help counter side effects of hyperthyroidism like high bp, rapid heart rate, nervousness. ...Read more

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What does ptu (propylthiouracil) means and the side effects?

Propylthiouracil: Ptu (propylthiouracil) is used to treat hyperthyroidism. It is very effective to cool down the hyperthyroidism. Although it is generally well tolerated, it can cause a rash. More serious side effects are low white blood cell count, making you prone to infections, and liver injury. Another drug, methimazole, has less liver toxicity, and is usually preferred over ptu. ...Read more

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Can you tell me more about bad reaction to propylthiouracil (ptu) manufactured by purepac?

Rash: Hi. The most common adverse reaction to PTU (propylthiouracil) is a rash. Some of these people can be switched to methimazole and do fine. The serious side effect we worry about is neutropenia (low white blood cell type that fights bacterial infection). The problems go away with stopping the drug. You might want to proceed thy radioactive iodine therapy. ...Read more

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Since being on 600mg of PTU, (propylthiouracil) I've been experiencing constant chest and back pains, is it related??

Since being on 600mg of PTU, (propylthiouracil) I've been experiencing constant chest and back pains, is it related??

Depends: Hyperthyroid alone which is what the ptu (propylthiouracil) is supposed to treat can cause chest and back pain as well so it's difficult to know if the disease or the pill is doing it. Ptu (propylthiouracil) is not a good option for hyperthyroidism. Talk to your doctor about Methimazole instead. ...Read more

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When measuring calcium...What is ptu (propylthiouracil)? And what does 164 mean for me? What is the norm for 41 years old?

Pth?: I think you meant PTH instead of ptu (propylthiouracil). The normal values vary with the lab that you went to so you need to look at the normal range that came with the lab. In my lab, 60 is the highest normal so 164 would be high. ...Read more

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Is ptu (propylthiouracil) safe when you are pregnant?

Is ptu (propylthiouracil) safe when you are pregnant?

Yes if needed: Ptu (propylthiouracil) is the treatment for hyperthyroidism. It is very important that hyperthyroidism be well controlled and treated during pregnancy. Not treating it can be dangerous. This is an important medication for patients to take if they have hyperthyroidism in pregnancy. ...Read more

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Which is more effective ptu (propylthiouracil) or methimazole?

PTU (propylthiouracil): May be more effective as it blocks peripheral conversion of T4 to t3 (liothyronine) in body, but

it has somewhat greater risk side effects. ...Read more

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Been on ptu (propylthiouracil) for 13 days will the breathing issue stop?

Been on ptu (propylthiouracil) for 13 days will the breathing issue stop?

Call your doctor: If you're having trouble breathing on ptu, (propylthiouracil) please contact your doctor asap. ...Read more

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Breathing issues before taking ptu (propylthiouracil). Will the ptu (propylthiouracil) help the problem is it due to hyperthyriod?

Breathing issues before taking ptu (propylthiouracil). Will the ptu (propylthiouracil) help the problem is it due to hyperthyriod?

Might be: If you've been having difficulty breathing since before starting ptu, (propylthiouracil) as opposed to after you started, you still need to contact your doctor about this. Heart problems, etc. Associated with hyperthyroidism should be investigated if not already. Difficulty breathing is something which merits a doctor's attention. ...Read more

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Is everyone using ptu (propylthiouracil) for graves disease?

No: There are essentially three approaches to managing hyperthyroidism: surgical removal of gland, radiation therapy to the gland, medication (tapazole, propylthiouracil) to block the gland from taking up iodine and forming too much hormone. The symptoms must be treated often first with beta-blocker. Treatment options need by discussed and tailored for each person, depending on age, other probs, etc. ...Read more

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I have hyperthyroidism. Is taking ptu (propylthiouracil) ok in pregnancy?

Category "D": Ptu (propylthiouracil) works by preventing a final stage of thyroid hormone assembly in the gland. The fetal gland is generally finished forming by 11wks, & they begin to make their own hormone. While most would avoid ptu (propylthiouracil) after 11 wks, it is a better choice for early pregnancy than some alternatives. You need to discuss your pregnancy concerns with your dr & come up with a plan that works for u & baby. ...Read more

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Can I take ptu (propylthiouracil) in pregnancy?

Can I take ptu (propylthiouracil) in pregnancy?

Yes if needed: Ptu (propylthiouracil) is the treatment for hyperthyroidism. It is very important that hyperthyroidism be well controlled and treated during pregnancy. Not treating it can be dangerous. This is an important medication for patients to take if they have hyperthyroidism in pregnancy. ...Read more

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I'm having severe (even rare) side effects of ptu (propylthiouracil). Do I call my endo?

I'm having severe (even rare) side effects of ptu (propylthiouracil). Do I call my endo?

YES!!: Ptu (propylthiouracil) earned a black box label from the fda because it may cause liver failure. Other side effects might include suppression of infection fighting cells in the bone marrow, rash, and joint swelling. Please contact your doctor right away! ...Read more

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Done an sgpt test and it says on the result that mine is 66 (ref: 9.00-52 u/l (h). Do I need to worry? I am drinking ptu (propylthiouracil) for my thyroidism continuously

PTU (propylthiouracil) and liver: Drugs like ptu (propylthiouracil) and Methimazole can cause liver toxicity but hyperthyroidism can also cause elevation int the liver enzyme test you had done. If your still early in your treatment and your thyroid hormone levels (free t4) is still high it could be that. Hope this helps. ...Read more

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What you think of my prognosis if my labs are like this tsh0.025 frm 0.013 nd ft3 4.82 frm 6.10 after taking methimazole for 21dys but im on ptu (propylthiouracil) now?

Getting better: It takes many weeks (typically 6 weeks) for Methimazole or ptu (propylthiouracil) to bring thyroid levels down to normal. The TSH will remain low even after your thyroid level is normal, because it takes time for the pituitary gland to recover from the high levels. At this time, just follow the thyroid level and remain on medication. ...Read more

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21 weeks preg, stopped PTU (propylthiouracil) about 2 months ago because it makes me sick, endo refuses to give me different meds. Should I seek a new endo? No to PTU (propylthiouracil)!!

Yes: If you are not going to follow the advice of the endocrinologist you need to find one you can trust and work with. Thyroid disease is very serious in pregnancy and can effect your baby's whole life if it isn't treated right. You might discuss seeing a specialist in high risk pregnancies too since it is a bit different when you are treating 2 patients instead of just 1.Best wishes for u and the baby ...Read more

Dr. Sheila Smith
49 Doctors shared insights

Ptu (Definition)

PTU is a thyroid agent which is a ...Read more


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