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Doctor insights on: Ptu Allergy In Children

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Tell me about ptu (propylthiouracil) effects/?

Tell me about ptu (propylthiouracil) effects/?

Liver toxicity: Fulminant hepatic failure is the most serious adverse effect (black warning exist for such risk). Other side effects include rash, joint pain and rarely bone marrow suppression. ...Read more

Dr. John Chiu
2,638 Doctors shared insights

Allergies (Definition)

Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more


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Should I be worried that I have gained 30 lbs in 6 months on ptu (propylthiouracil)?

Should I be worried that I have gained 30 lbs in 6 months on ptu (propylthiouracil)?

Had you lost weight?: Many hyperthyroid patients lose a lot of weight prior to diagnosis. Once treatment becomes effective, the weight comes back. Thyroid function tests should be monitored carefully as it's easy to become hypothyroid on ptu, (propylthiouracil) which would predispose to further weight gain. ...Read more

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Can I take ptu (propylthiouracil) in pregnancy?

Can I take ptu (propylthiouracil) in pregnancy?

Yes if needed: Ptu (propylthiouracil) is the treatment for hyperthyroidism. It is very important that hyperthyroidism be well controlled and treated during pregnancy. Not treating it can be dangerous. This is an important medication for patients to take if they have hyperthyroidism in pregnancy. ...Read more

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I'm having severe (even rare) side effects of ptu (propylthiouracil). Do I call my endo?

I'm having severe (even rare) side effects of ptu (propylthiouracil). Do I call my endo?

YES!!: Ptu (propylthiouracil) earned a black box label from the fda because it may cause liver failure. Other side effects might include suppression of infection fighting cells in the bone marrow, rash, and joint swelling. Please contact your doctor right away! ...Read more

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What are other medications for surgery other than carbimazole and propylthiouracil (ptu) and how effective are they?

What are other medications for surgery other than carbimazole and propylthiouracil (ptu) and how effective are they?

Don't understand: These drugs are used in the treatment of hypothyroidism. I am assuming you mean are they effective in the treatment of hyperthyroidism. That is something you need to discuss with you physician and endocrinologist. There are many causes of hyperthyroidism and it will depend on that. ...Read more

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My weight is raising after get medication for hyperthiroidism. Can I do exercise? I want standard weight now. Fyi doc here give me ptu (propylthiouracil) and propanol

Hyperthyroidism: Ptu (propylthiouracil) & propanolol are standard drugs used to treat an overactive thyroid (hyperthyroidism) which can lead to weight loss & fast heart rate. Propanolol is a beta blocker that keeps your heart from beating too fast. As ptu (propylthiouracil) normalizes an overactive thyroid, you stop losing weight & return to your normal weight by gaining it back. Healthy nutrition & regular exercise are always good. ...Read more

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Done an sgpt test and it says on the result that mine is 66 (ref: 9.00-52 u/l (h). Do I need to worry? I am drinking ptu (propylthiouracil) for my thyroidism continuously

PTU (propylthiouracil) and liver: Drugs like ptu (propylthiouracil) and Methimazole can cause liver toxicity but hyperthyroidism can also cause elevation int the liver enzyme test you had done. If your still early in your treatment and your thyroid hormone levels (free t4) is still high it could be that. Hope this helps. ...Read more

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What you think of my prognosis if my labs are like this tsh0.025 frm 0.013 nd ft3 4.82 frm 6.10 after taking methimazole for 21dys but im on ptu (propylthiouracil) now?

Getting better: It takes many weeks (typically 6 weeks) for Methimazole or ptu (propylthiouracil) to bring thyroid levels down to normal. The TSH will remain low even after your thyroid level is normal, because it takes time for the pituitary gland to recover from the high levels. At this time, just follow the thyroid level and remain on medication. ...Read more

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21 weeks preg, stopped PTU (propylthiouracil) about 2 months ago because it makes me sick, endo refuses to give me different meds. Should I seek a new endo? No to PTU (propylthiouracil)!!

Yes: If you are not going to follow the advice of the endocrinologist you need to find one you can trust and work with. Thyroid disease is very serious in pregnancy and can effect your baby's whole life if it isn't treated right. You might discuss seeing a specialist in high risk pregnancies too since it is a bit different when you are treating 2 patients instead of just 1.Best wishes for u and the baby ...Read more

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Is everyone using ptu (propylthiouracil) for graves disease?

No: There are essentially three approaches to managing hyperthyroidism: surgical removal of gland, radiation therapy to the gland, medication (tapazole, propylthiouracil) to block the gland from taking up iodine and forming too much hormone. The symptoms must be treated often first with beta-blocker. Treatment options need by discussed and tailored for each person, depending on age, other probs, etc. ...Read more

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I have hyperthyroidism. Is taking ptu (propylthiouracil) ok in pregnancy?

Category "D": Ptu (propylthiouracil) works by preventing a final stage of thyroid hormone assembly in the gland. The fetal gland is generally finished forming by 11wks, & they begin to make their own hormone. While most would avoid ptu (propylthiouracil) after 11 wks, it is a better choice for early pregnancy than some alternatives. You need to discuss your pregnancy concerns with your dr & come up with a plan that works for u & baby. ...Read more

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For how long time did ptu (propylthiouracil) taken?

For how long time did ptu (propylthiouracil) taken?

PTU (propylthiouracil): Ptu (propylthiouracil) has an ongoing risk on bone marrow suppression and liver toxicity which is low but real. Some, but not all practitioners limit it's use to 1-2 years and then move to permanent management like radioactive iodine or surgery. ...Read more

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Can you have a bad reaction to propylthiouracil (ptu)?

Can you have a bad reaction to propylthiouracil (ptu)?

It's possible.: Ptu (propylthiouracil) can cause a skin reaction (hives, rarely), liver problems (more rare, but that's why it's use is severely restricted these days), and a drop in the white blood cell count (extremely rare). ...Read more

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Is it possible for a person to have a bad reaction to propylthiouracil (ptu)?

Is it possible for a person to have a bad reaction to propylthiouracil (ptu)?

Absolutely: The fda has a black box warning on ptu (propylthiouracil) because it has been linked to liver failure in some. It can also cause failure of bone marrow to make certain type of immune cells. Rash and large joint inflammation are also known side effects. Methimazole is the anti-thyroid drug of choice in most. Although there are similar side effects between the two drugs, Methimazole may be safer for liver than ptu (propylthiouracil). ...Read more

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What's the maximum milligrams of ptu (propylthiouracil) a person can take daily?

Depends: Unless you are pregnant, we usually use Methimazole before ptu (propylthiouracil) because of the occasional liver problems with ptu (propylthiouracil). The dose has to be individual depending on the severity of the hyperthyroidism and the breakdown rate in your body. Some people have a very rapid breakdown and require very high doses to be controlled. If so, you need very close monitoring to use the lowest effective dose. ...Read more

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Is ptu (propylthiouracil) safe when you are pregnant?

Is ptu (propylthiouracil) safe when you are pregnant?

Yes if needed: Ptu (propylthiouracil) is the treatment for hyperthyroidism. It is very important that hyperthyroidism be well controlled and treated during pregnancy. Not treating it can be dangerous. This is an important medication for patients to take if they have hyperthyroidism in pregnancy. ...Read more

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Which is more effective ptu (propylthiouracil) or methimazole?

PTU (propylthiouracil): May be more effective as it blocks peripheral conversion of T4 to t3 (liothyronine) in body, but

it has somewhat greater risk side effects. ...Read more

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Been on ptu (propylthiouracil) for 13 days will the breathing issue stop?

Been on ptu (propylthiouracil) for 13 days will the breathing issue stop?

Call your doctor: If you're having trouble breathing on ptu, (propylthiouracil) please contact your doctor asap. ...Read more

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Breathing issues before taking ptu (propylthiouracil). Will the ptu (propylthiouracil) help the problem is it due to hyperthyriod?

Breathing issues before taking ptu (propylthiouracil). Will the ptu (propylthiouracil) help the problem is it due to hyperthyriod?

Might be: If you've been having difficulty breathing since before starting ptu, (propylthiouracil) as opposed to after you started, you still need to contact your doctor about this. Heart problems, etc. Associated with hyperthyroidism should be investigated if not already. Difficulty breathing is something which merits a doctor's attention. ...Read more

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What can I expect after having a thyroidectomy and radioiodine treatment for ptu (propylthiouracil)?

What can I expect after having a thyroidectomy and radioiodine treatment for ptu (propylthiouracil)?

Hypothyroidism: Lifelong need for thyroid hormone replacement. Watch calcium and parathyroid function as well. Endocrinologist needs to monitor for recurrence of cancer (i presume that's why you had these procedures) ...Read more

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I've been taking 350mg of ptu (propylthiouracil) in one go, since doing this, I'm experiencing pain in the upper right side of my stomach, what should I do?

I've been taking 350mg of ptu (propylthiouracil) in one go, since doing this, I'm experiencing pain in the upper right side of my stomach, what should I do?

Evaluation: Ptu (propylthiouracil) is typically taken 3 times daily. Although your total dose of 350 mg is not excessive, it should be divided up throughout the day. One of the possible side effects of ptu (propylthiouracil) is a type of drug related hepatitis. This could cause right upper abdominal pain. You should get this evaluated by your doctor. ...Read more

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Taken carbimazole and ptu (propylthiouracil) in the past for my thyroid, but they are not improving my condition, is there any other anti- thyroid drugs I can take?

Taken carbimazole and ptu (propylthiouracil) in the past for my thyroid, but they are not improving my condition, is there any other anti- thyroid drugs I can take?

Methimazole is also: Available and then there is radioiodine -- but any of the antithyroid drugs will work if taken at adequate doses for long enough to deplete stored up, previously manufactured, thyroid hormone. Check w/your doctor. ...Read more

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Having a total thyroidectomy on Tuesday for GD but PTU (propylthiouracil) has caused low t4/ft3 (ft3 0.8) I know I can't have the surgery hyper but is hypo a Problem?

Thyroid replacement: Once your thyroid has been removed, you will need thyroid replacement to normalize your metabolic function since you will no longer produce any thyroid hormones. Let your doctor guide you through the dose adjustment process. ...Read more

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I was told I have hashitoxicosis. Is there a way to treat it? I was on ptu (propylthiouracil) for 2 years because the dr said I had hyperthyroidism. I no longer take ptu (propylthiouracil)

I was told I have hashitoxicosis. Is there a way to treat it? I was on ptu (propylthiouracil) for 2 years because the dr said I had hyperthyroidism. I no longer take ptu (propylthiouracil)

Hashitoxicosis: Graves disease and hashimoto's thyroiditis are both autoimmune thyroid disorders. In typical graves, the antibodies make the thyroid overactive. In typical hashi, the antibodies destroy the thyroid. Sometimes both occur together; you can be hyperthyroid, and eventually "burn out" and become normal, or hypothyroid. So what is your thyroid doing now? Follow the advice of your endocrinologist. ...Read more

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How does ptu (propylthiouracil) beta blocker effect teen?

How does ptu (propylthiouracil) beta blocker effect teen?

Different drugs: Ptu (propylthiouracil) is a drug used to block the thyroid from making thyroid hormones in patients primarily with grave's disease. It has potential serious toxicities involving both liver and bone marrow. Methimazole may be safer, though also has toxicities. Blood work is monitored closely. Beta blockers are medications which help counter side effects of hyperthyroidism like high bp, rapid heart rate, nervousness. ...Read more

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What does ptu (propylthiouracil) means and the side effects?

Propylthiouracil: Ptu (propylthiouracil) is used to treat hyperthyroidism. It is very effective to cool down the hyperthyroidism. Although it is generally well tolerated, it can cause a rash. More serious side effects are low white blood cell count, making you prone to infections, and liver injury. Another drug, methimazole, has less liver toxicity, and is usually preferred over ptu. ...Read more

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Can you tell me more about bad reaction to propylthiouracil (ptu) manufactured by purepac?

Rash: Hi. The most common adverse reaction to PTU (propylthiouracil) is a rash. Some of these people can be switched to methimazole and do fine. The serious side effect we worry about is neutropenia (low white blood cell type that fights bacterial infection). The problems go away with stopping the drug. You might want to proceed thy radioactive iodine therapy. ...Read more

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What is the difference between ptu (propylthiouracil) and carbimazole? Is it possible to switch medication?

Different: Carbimazole is converted to an anti=thyroid drug methimazole. Ptu (propylthiouracil) is a different anti-thyroid drug. Both are effective. Ptu (propylthiouracil) better, but not used as much since it can be associated with liver disease. Both have potential side effects. Talk w/your doctor. ...Read more

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Since being on 600mg of PTU, (propylthiouracil) I've been experiencing constant chest and back pains, is it related??

Depends: Hyperthyroid alone which is what the ptu (propylthiouracil) is supposed to treat can cause chest and back pain as well so it's difficult to know if the disease or the pill is doing it. Ptu (propylthiouracil) is not a good option for hyperthyroidism. Talk to your doctor about Methimazole instead. ...Read more

Dr. Kenneth Pennington
100 Doctors shared insights

Propylthiouracil (Definition)

Propythiouracil (PTU) can be used to control an overactive thyroid in the first trimester. PTU should be used with caution or avoided in the second and third trimester to ...Read more


Dr. Janice Alexander
49 Doctors shared insights

Ptu (Definition)

PTU is a thyroid agent which is a ...Read more