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Doctor insights on: Pth In Osteoporosis

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Ionized Calcium 4.65, PTH 133, Calcium 10.3, Vitamin D 7, Phosphorus 4.9, recurrent Kidney stones. Thyroid lobe, two parathyroids removed in 2004.

Ionized Calcium 4.65, PTH 133, Calcium 10.3, Vitamin D 7, Phosphorus 4.9, recurrent Kidney stones. Thyroid lobe,  two parathyroids removed in 2004.

Uncertain: These test results don't add up to a straight forward answer. However, I would be concerned about the possibility of recurrent primary hyperparathyroidism. You should take Vit D to eliminate Vit D deficiency as a cause for high PTH levels. Once this is done, if you still have high PTH with high calcium levels, you have recurrent primary HPTH and will need surgery again. ...Read more

Parathyroid Hormone (Definition)

Parathormone or parathyrin, is secreted by the chief cells of the parathyroid gland. It acts to increase the concentration of calcium ...Read more


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Vitamin d was 15.6 ng/ml and normal calcium high in pth and alkaline phosphatase serum level?

Vitamin d was 15.6 ng/ml and normal calcium high in pth and alkaline phosphatase serum level?

Replace vitamin d: Vitamin d deficiency is very common. You need vitamin d to absorb calcium from the intestines. When you don't have enough vitamin d, in order to keep your blood calcium levels normal, your make more PTH to pull calcium from the bones and that raises the alkaline phosphatase. Replacing vitamin d should normalize all the tests. ...Read more

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Could a severe vitamin d deficiency mask primary hyperparathyroidism by lowering serum calcium levels? [would u see low-normal calcium and high pth?]

Could a severe vitamin d deficiency mask primary hyperparathyroidism by lowering serum calcium levels? [would u see low-normal calcium and high pth?]

Masking: Masking of hyperpara with low D is unusual. 40% of hyperpara patients present with vitamin D deficiency. It is important to get all labs checked at the same time (blood draw) to prevent confounding results from tine of day or day to day changes. The labs I check are: total calcium, ionized calcium, 25 OH vitamin D, magnesium, phosphorus, creatinine, chloride, and intact PTH. ...Read more

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My pth level161 low vitatamin d high calcium and diabetes how danger is?

My pth level161 low vitatamin d high calcium and diabetes how danger is?

HPT: You have hyperparathyroidism. If left untreated, your risks of heart attack, stroke, osteoporosis, and chronic kidney disease are ALL increased. This will compound the effects of your diabetes. It’s very hard/impossible to cure diabetes but hyperparathyroidism can be cured with surgery. I recommend you fix what you can. ...Read more

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Why is vitamin d important in preventing osteoporosis?

Why is vitamin d important in preventing osteoporosis?

Yes: It's important for most people to supplement with calcium and vitamin d for good bone health. A simple blood test can be used to check for vitamin d deficiency. ...Read more

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How does parathyroid hormone lower calcium levels?

How does parathyroid hormone lower calcium levels?

Parathyroid hormone: Normal parathyroid hormone levels does not lower calcium levels. A low parathyroid level will lower calcium. A low calcium may increase parathyroid levels. Please discuss further with your doctor. ...Read more

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What causes low serum phosphate other than parathyroidism? PTH & calcium are constantly normal. Normal D vitamin because of high dose supplements.

What causes low serum phosphate other than parathyroidism? PTH & calcium are constantly normal. Normal D vitamin because of high dose supplements.

Low phos: Phos metabolism is intake /shift/ losses. I am assuming you have good intake. So the other two are the reason, either shift inside the cells or losses from the kidney. How low is the phos? Your medication list shows no meds that can cause losses. A lab doesn't need to be treated, so rpt lab and then get a urine fractional excretion if still low. Talk to your MD. ...Read more

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Can calcium deficiency cause multiple broken arms? 50 # total but osteoporosis only in left leg not arms. Low calcium levels med-high impact falls

Can calcium deficiency cause multiple broken arms? 50 # total but osteoporosis only in left leg not arms. Low calcium levels med-high impact falls

Most likely not: Hypocalcemia needs confirmation by measurement of the serum ionized calcium level. When the diagnosis is confirmed by the finding of a serum calcium level lower than 8.2 mg/dl or an ionized calcium level lower than 4.4 mg/dl attention should turn toward seeking the cause. When we find the cause the treatment will directed to that. Heck with endocrinologists. Good luck. ...Read more

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Low pth, serum calcium 10.9 intact calcium 5.8 osteoepenia (62 yrs). Slightly low vit d feeling great. Could there be any other cause besides cancer?

Low pth, serum calcium 10.9 intact calcium 5.8 osteoepenia (62 yrs). Slightly low vit d feeling great.  Could there be any other cause besides cancer?

Yes: Unless you have been previously diagnosed with cancer- i wouldn't worry about it. Low PTH and low calcium are not typically signs of cancer unless caused by cancer related malnutrition - which is typically obvious. Most likely you just need more vit d (or sunlight) and calcium supplementation. An endocrinologist can help you. Also - malabsorption can cause this -for example post gastric bypass. ...Read more

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Why are serum calcium and ACE levels increased in sarcoidosis?

Why are serum calcium and ACE levels increased in sarcoidosis?

Not known.: No one knows exactly why high calcium levels occur in granuloma-forming disorders such as sarcoidosis. Contributing factors may include dehydration, increased uptake of oral calcium and/or decreased calcium excretion, especially if the kidneys are not 100% functional. ACE activity is also increased, but again no one knows exactly why. ACE is thought to be produced by cells in the granulomas. ...Read more

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Do familial hypocalciuric hypercalcemia patients respond to taking vitamin d supplements with an increased calcium, or is the calcium level stable?

Do familial hypocalciuric hypercalcemia patients respond to taking vitamin d supplements with an increased calcium, or is the calcium level stable?

No Change....needed?: In fbhh, the problem lies in the parathyroid perception of ca concentration. The ca sensing receptor (casr) doesn't sense the ca level correctly, resulting in PTH being elevated and kidney resorption increasing. While ca-vit d increases abdominal absorption, it doesn't change the underlying error. Additionally, these patients do not get kidney stones/osteoporosis at an increased rate (asympt). ...Read more

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Why r my calcium levels normal, while my ionized calcium levels are high? I have bone pain, fatigue, kidney stones. I don't know pth level, or vit. D.

Why r my calcium levels normal, while my ionized calcium levels are high? I have bone pain, fatigue, kidney stones.  I don't know pth level, or vit. D.

Half if calcium: In the blood is bound to proteins and inactive. The other, active, half is the ionized or free calcium, which is what really does the heavy lifting and is more accurate cllinically. You really need the other lab and a good endocrinologist. ...Read more

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Are low vitamin d levels, bone loss and breast nodules related?

Are  low vitamin d levels,  bone loss and breast nodules  related?

Yes : They can be, get your d levels up and see what happens. Ideal levels are between 50 and 70. ...Read more

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Is it really possible to go from t-3.7 severe osteoporosis score to t-2.3 osteopenia in the spine in 7 months by taking strontium ranelate?

Is it really possible to go from t-3.7 severe osteoporosis  score to t-2.3 osteopenia in the spine  in 7 months by taking strontium ranelate?

See below: It has been said. That strontium can increase bone density test, but this may appear more impressive than it really is because strontium in bone can affect bone density interpretation. Radiologist needs to be informed if you are taking strontium. ...Read more

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Hx of kid stones, high protein dt , calcium high in 24 hr urine, serum calc 10.3 at highest .Vit d low norm intact pth 41. Nodules in wrist w pain. ? Asked this before but put TSH instead of pth !

Hx of kid stones, high protein dt , calcium high in 24 hr urine, serum calc 10.3 at highest .Vit d low norm intact pth 41. Nodules in wrist w pain. ? Asked this before but put TSH instead of pth !

Primary hyperpara: A PTH of 41 with a concurrently high calcium of 10.3 is not normal. Pth and calcium level correlate (inversely) very closely with each other. If ur calcium is high at 10.3, there shouldn't be any PTH around & the level should drop to 5 or 10 but not 41. I would have a frank discussion with ur doctor about possibility of primary hyperparathyroidism (high calcium, kidney stone, high urine calcium). ...Read more

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Low vitamin D level (19), High phosphorus level (4.5), High PTH level (70). What could be the cause of this? Serum Calcium level is normal.

Low vitamin D level (19), High phosphorus level (4.5), High PTH level (70). What could be the cause of this? Serum Calcium level is normal.

Treat low vit D: I would get the low vitamin D treated and then recheck the labs. The 25OH vit D should be above 30. This will likely correct any of the other mild reported lab abnormalities. ...Read more

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High levels of calcium in my blood and my parathyroid hormone is -3. Is this symptoms of cancer.?

High levels of calcium in my blood and my parathyroid hormone is -3. Is this symptoms of cancer.?

Many causes: There are many causes of high serum calcium. In your case it is not due to hyperactivity of parathyroid gland but it is not feasible to say why your calcium is high without additional information. See this site for more info on this subject. http://www.mayoclinic.com/health/hypercalcemia/ds00976/dsection=causes. ...Read more

Dr. PHILIP WALLER
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Osteoporosis (Definition)

A condition in which bones ...Read more