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Doctor insights on: Psoriatic Arthritis With Negative Ra Ana

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What is the difference between psoriatic arthritis and rheumatoid arthritis?

What is the difference between psoriatic arthritis and rheumatoid arthritis?

Different types: Although they are both called arthritis, they are two very different types. Each one has different causes and different manifestations. There can be certain similarities of therapy. We need to define each one because our clinical program, our clinical evaluation, and our therapy can differ. They have different types of immunologic processes involved in each of these. There are over 100 different types of arthritis. ...Read more

Dr. Thomas Namey
2,422 Doctors shared insights

Arthritis (Definition)

A condition where there is progressive degeneration of one or more joints. Symptoms may include joint pain, swelling, decreased motion, and stiffness. The two most common types of arthritis are osteoarthritis, which is associated first with articular cartilage breakdown with a component of inflammation, and rheumatoid arthritis, which is a systemic autoimmune disorder that affects joint linings first and secondarily ...Read more


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What are the basic differences in symptoms and clinical menifestations between Psoriatic arthritis and Rheumatoid arthritis?

What are the basic differences in symptoms and clinical menifestations between Psoriatic arthritis and Rheumatoid arthritis?

Less symetrical: Psoriatic arthritis comes in several forms. The main difference between RA and the type of psoriatic arthritis that is closest to rheumatoid is that psoriatic is less symetrical. Psoriatic is also associated with nail changes, more tendinitis problems, and psoriasis. It is very rare for RA to affect DIP (joints at end of finger). Psoriatic will affect these. There are many other small diff. ...Read more

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Which disease usually has the best prognosis: 1. SLE, 2. Rheumatoid arthritis, 3. Psoriasis or 4. Psoriatic Arthritis?

Which disease usually has the best prognosis: 1. SLE, 2. Rheumatoid arthritis, 3. Psoriasis or 4. Psoriatic Arthritis?

Impossible to say: It depends on the severity of each disease. Psoriatic would be considered the most benign. ...Read more

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Is it possible to have psoriatic arthritis and test negative for arthritis?

Is it possible to have psoriatic arthritis and test negative for arthritis?

Psoriatic arthritis: Hi Sharon, Psoriatic arthritis is under the umbrella of spondylo-arthritis. This group of arthritis has a genetic test for Human Leukocyte Antigen B27 (HLA B27). A positive test means HLA-B27 is present. About 50% of patients with psoriatic arthritis test positive for HLA B27, therefore a negative test does not exclude the diagnosis. I hope that is helpful. Thank you, Nisha ...Read more

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Recently doc told me I have psoriatic arthritis. But all blood tests negative and never any swelling. Sounds reasonable?

Recently doc told me I have psoriatic arthritis. But all blood tests negative and never any swelling. Sounds reasonable?

Psoriatic Arthritis: No single test can confirm a diagnosis of psoriatic arthritis. But some types of tests can rule out other causes of joint pain, such as rheumatoid arthritis or gout. Diagnosis tests may include: x-rays, magnetic resonance imaging (mri), rheumatoid factor (rf), or a joint fluid test. Rf is an antibody that's often present in the blood of people with rheumatoid arthritis, not usually psoriatic arthr. ...Read more

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Mild Psoriasis sufferer, chronic pain right forarm & elbow. Blood tests 80 titre ana, positive anticentromere. Psoriatic arthritis or scleroderma?

Mild Psoriasis sufferer, chronic pain right forarm & elbow. Blood tests 80 titre ana, positive anticentromere. Psoriatic arthritis or scleroderma?

Occam's Razor: The simplest explanation is most the likely one. Usually Systemic Sclerosis and/or limited Scleroderma is not characterized by arthritis like you describe. The typical biomarker is anti Scl-70 (anti-topoisomerase). Symptoms have to be put into a broader context and be characterized beyond elbow and forearm pain. This one you should see a rheumatologist about. Dermatology would be useful as well. ...Read more

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What can I do to treat psoriatic arthritis?

What can I do to treat psoriatic arthritis?

See your doctor.: A rheumatology referral may be necessary, but a nsaid, with sulfasalazine and Methotrexate given once weekly are my first treatments. The biologics work (enbrel, humira, (adalimumab) remicade) work, but are quite expensive, not generic, require prior authorization, and almost always require prior Methotrexate therapy. Leflunomide, azothioprine, and Cyclosporine are options, given by someone in rheumatology! ...Read more

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What can be done to cure psoriatic arthritis?

What can be done to cure psoriatic arthritis?

Psoriatic Arthritis: There are multiple treatments for psoriatic arthritis to control symptoms. It has also been associated with higher rates in smokers. Stop smoking if you do and see a rheumatologist for discussion of the best treatment for you. ...Read more

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Is it possible to get psoriatic arthritis young?

Yes: It is more typical for psoriatic arthritis to start when you are young. Usually, around 30, but you can get it at any age. ...Read more

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I know someone with psoriatic arthritis, what is the cure?

No cure, but remitts: Few people should face significant joint issues, if this most common of rheumatic diseases was diagnosed early and treated with remitting agents once diagnosed. If you have no sx, do you have disease? ...Read more

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Psoriatic arthritis --- what can I generally expect later in life?

Psoriatic arthritis --- what can I generally expect later in life?

Depends...: ...On what you do now. Multiple treatments, ranging from oral medications to biologics like enbrel, humira, and stelara, (ustekinumab) are effective in treating psoriatic arthritis and preventing damage to joints. If you do not address the problem now, your joints will suffer damage in later life and your mobility will be compromised. See a dermatologist skilled in psoriasis treatment asap. ...Read more

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If I had psoriasis does it mean I have psoriatic arthritis if I have arthritis?

If I had psoriasis does it mean I have psoriatic arthritis if I have arthritis?

See below: You are at increased risk for developing psoriatic arthritis if you have psoriasis and depending on which study you look at, 10 to 40% of all patients with psoriasis will develop psoriatic arthritis. ...Read more

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What do psoriatic arthritis nodules look like?

What do psoriatic arthritis nodules look like?

None: Psoriatic arthritis typically does not cause nodules. Skin and lung and eye nodules typically occur with rheumatoid arthritis. ...Read more

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Can alcohol cause psoriatic arthritis to flair?

Can alcohol cause psoriatic arthritis to flair?

Sometimes: There needs to be more research but there is evidence showing that those who drink alcohol regularly have a greater risk of psoriasis, and many who have psoriasis & psoriatic arthritis note that their symptoms flare with alcohol use and improve when they avoid it; but this likely is not true for everyone who has psoriasis. See http://www. Medpagetoday. Com/dermatology/psoriasis/23999. ...Read more

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Is Psoriatic Arthritis in the spine very severe a disease?

Is Psoriatic Arthritis in the spine very severe a disease?

Varies: It varies tremendously based upon the severity of the arthritis. Some may have minimal symptoms, or others can have cares that are quite debilitating. I would certainly be seen by a rheumatologist as well as a spinal specialist. ...Read more

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What does doctors usually presribe for psoriatic arthritis?

What does doctors usually presribe for psoriatic arthritis?

Methotrexate, TNFs: Methotrexate is usually the most common initial therapy. Tnf agents such as remicade, (infliximab) Enbrel or Humira are also extremely effective, especially if Methotrexate alone is not sufficient. ...Read more

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What is the best way to prevent psoriatic arthritis flare ups?

What is the best way to prevent psoriatic arthritis flare ups?

See below: Take your medicine and if it is not working meet with your rheumatologist to adjust your regimen. Also reduce stress in your life as this can trigger flares. ...Read more

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Has any one taken the disease modifying drug (dmards) for their psoriatic arthritis?

Has any one taken the disease modifying drug (dmards) for their psoriatic arthritis?

Most patients need a: Psoriatic arthritis can be a very inflammatory disease. We all want pain relief for our patients, but rheumatologists understand the need to reduce inflammation, because it portends coniued damge to joints, as well as much earlier cardiac disease. My personal favorites: sulfasalazine with methotrexate, the latter given sc. Some, albeit few, patients need tnf-alpha inhibitors. ...Read more

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Looking for naturopaths who could treat psoriatic arthritis?

Why?: They are no effective naturopathic therapies. See a dermatologist instead. ...Read more

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What does psoriatic arthritis in the neck feel like usually?

What does psoriatic arthritis in the neck feel like usually?

Achy: Achy pain with and without movement that produces stiffness in themorning and gradually improves overseveral hours. It is not visible on xray or normal lab tests but has been detected by mri, although that test is overused, most ofthe time. ...Read more

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I have psoriatic arthritis but no swelling. Is that possible?

I have psoriatic arthritis but no swelling. Is that possible?

Yes: Psoristic arthritis can cause pain and other symptoms before any swelling becomes evident. That said you need to make sure that nothing else is causing those symptoms ...Read more

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Is there any correlation between amyloidosis, psoriatic arthritis, and spondilitis?

Is there any correlation between amyloidosis, psoriatic arthritis, and spondilitis?

Some: Hi micheleg1,
there is some evidence of the presence of amyloidosis in patients with psoriatic arthritis and, what I'm assuming you mean to be anklylosing spondylitis.
The clinical significance of this, however, remains unclear at this point. ...Read more

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How much effective is sulfasalazine in psoriatic arthritis?

How much effective is sulfasalazine in psoriatic arthritis?

It is considered...: Sulfasalazine is one of the first-line therapies for psoriatic arthritis at doses of 1-3 grams per day. It is moderately effective in studies, but is usually combined with other drugs! ...Read more

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How exactly does a doctor go about diagnosing psoriatic arthritis?

Mostly clinical: Skin lesions and arthritis are the first step of evaluation ladder. The comes blood test, radiological evaluation. ...Read more

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Can psoriatic arthritis only cause pain in the si joint?

No: Much like rheumatoid arthritis almost any joint in the body can be affected with psoriatic arthritis - all the joints in th arms and legs as well as the cervical and lumbar spines. The si joints are typically involved in the spondylitic form of psoriatic arthritis. ...Read more

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Is there anything I can do for the swelling in my toe due to psoriatic arthritis?

Is there anything I can do for the swelling in my toe due to psoriatic arthritis?

If a focal joint: I would inject the toe with stroids and make sure you were on systemic meds like mtx or sulfasalazine. In refractory cases, Humira or Enbrel (etanercept) are last resort. ...Read more

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Is there anything I can do about the swelling in my joint due to psoriatic arthritis?

Is there anything I can do about the swelling in my joint due to psoriatic arthritis?

Psoriatic arthritis: Your doctor may recommend tumor necrosis factor-alpha (tnf-alpha) inhibitors if you have severe psoriatic arthritis. These drugs block the protein that causes inflammation in some types of arthritis and can improve signs and symptoms of psoriasis, as well. This group of drugs is the best to treat arthritis caused by psoriasis. ...Read more

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Can beetroot reduce methotrexate side effects in a psoriasis and psoriatic arthritis patient?

Can beetroot reduce methotrexate side effects in a psoriasis and psoriatic arthritis patient?

Not really!: Beet root is high in folic acid, but we routinely give Folic Acid to patients on methotrexate, usually 2mg/day. This would be overkill, and add unnecessary expense! ...Read more

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Is it possible to be put on methotrexate treatment for psoriatic arthritis & what was the outcome?

Is it possible to be put on methotrexate treatment for psoriatic arthritis & what was the outcome?

See details: Methotrexate is often a very effective treatment for psoriatic arthritis. The outcome depends on how well one responds to this med. About 70% will experience a good response. ...Read more

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I have severe pain on the ulnar side of my elbow. Could this be attributed to psoriatic arthritis?

I have severe pain on the ulnar side of my elbow. Could this be attributed to psoriatic arthritis?

Elbow pain: This could be ulnar neuropathy (cubital tunnel syndrome). Irritation/inflammation of the ulnar nerve as it passes within the cubital tunnel of the elbow can cause medial elbow pain, tingling sensations down the forearm into the hand with weakness in some muscles of the hand. Medial epicondylitis (golfer's elbow) is also a cause of 'inner elbow' or medial elbow pain. A consult with a physiatrist is. ...Read more

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My leg/knee won't straighten. Have diagnosis of psoriatic arthritis but what can I do to get leg to work properly?

My leg/knee won't straighten. Have diagnosis of psoriatic arthritis but what can I do to get leg to work properly?

Need evaluation: Sometimes when the knee "locks" or cannot straighten out fully, it means that there may be a tear in the cartilage (meniscus) preventing the knee from straightening. See an orthopedist or a physiatrist (rehab medicine specialist) and he/she should be able to help you with it. ...Read more

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I have 6 weekly blood tests (methotexate psoriatic arthritis) which often show elevated inflammation. Will this effect my organs?

Possibly: Methotrexate is a powerful medicine that must be used carefully. It can lead to a form of cirrhosis of the liver. Usually a liver biopsy is obtained every 2 years or so to look for evidence of side effects of the medicine. ...Read more

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Is it possible for someone to have psoriatic arthritis without ever having the skin condition? Specially if a parent has psoriasis?

Is it possible for someone to have psoriatic arthritis without ever having the skin condition? Specially if a parent has psoriasis?

Yes: Psoriatic arthritis can begin before a patient has psoriasis. In that case the diagnosis is made on clinical findings, and radiographs. Blood tests for rheumatoid arthritis are typically negative, but labs may show evidence of inflammation. ...Read more

Ana (Definition)

An "ana" is a blood test used to screen a person for the possibility of several autoimmune diseases. It is important to remember that this is a screening test and a positive result only indicates more testing may be warranted. No blood test is perfect, and getting to a diagnosis is usually much more complex than drawing blood and looking at a number ...Read more


Dr. Thomas Namey
1,030 Doctors shared insights

Psoriasis (Definition)

An autoimmune disease involving the skin, nails, and occasionally the joints. It is not contagious. There are several types of skin lesions, most common variety being large red scaly itchy plaques on extensor surfaces such as elbows and knees. Psoriasis can be controlled by a wide variety of medications, but a cure has ...Read more