Doctor insights on:
Psoriatic Arthritis With Negative Ra Ana
Different types: Although they are both called arthritis, they are two very different types. Each one has different causes and different manifestations. There can be certain similarities of therapy. We need to define each one because our clinical program, our clinical evaluation, and our therapy can differ. They have different types of immunologic processes involved in each of these. There are over 100 different types of arthritis. ...Read more
A condition where there is progressive degeneration of one or more joints. Symptoms may include joint pain, swelling, decreased motion, and stiffness. The two most common types of arthritis are osteoarthritis, which is associated first with articular cartilage breakdown with a component of inflammation, and rheumatoid arthritis, which is a systemic autoimmune disorder that affects joint linings first and secondarily ...Read more
What are the basic differences in symptoms and clinical menifestations between Psoriatic arthritis and Rheumatoid arthritis?
Less symetrical: Psoriatic arthritis comes in several forms. The main difference between RA and the type of psoriatic arthritis that is closest to rheumatoid is that psoriatic is less symetrical. Psoriatic is also associated with nail changes, more tendinitis problems, and psoriasis. It is very rare for RA to affect DIP (joints at end of finger). Psoriatic will affect these. There are many other small diff. ...Read more
Which disease usually has the best prognosis: 1. SLE, 2. Rheumatoid arthritis, 3. Psoriasis or 4. Psoriatic Arthritis?
Impossible to say: It depends on the severity of each disease. Psoriatic would be considered the most benign. ...Read more
Would any rheumatologist ever suggest enbrel (etanercept) to a patient who doesn't have rheumatoid arthritis, anspon, juvenile or psoriatic arthritis? Serious drug
Yes: Enbrel (etanercept) does have value in other disorders so I have recommended its use in diseases not on your list. ...Read more
Psoriatic arthritis: Hi Sharon, Psoriatic arthritis is under the umbrella of spondylo-arthritis. This group of arthritis has a genetic test for Human Leukocyte Antigen B27 (HLA B27). A positive test means HLA-B27 is present. About 50% of patients with psoriatic arthritis test positive for HLA B27, therefore a negative test does not exclude the diagnosis. I hope that is helpful. Thank you, Nisha ...Read more
Recently doc told me I have psoriatic arthritis. But all blood tests negative and never any swelling. Sounds reasonable?
Psoriatic Arthritis: No single test can confirm a diagnosis of psoriatic arthritis. But some types of tests can rule out other causes of joint pain, such as rheumatoid arthritis or gout. Diagnosis tests may include: x-rays, magnetic resonance imaging (mri), rheumatoid factor (rf), or a joint fluid test. Rf is an antibody that's often present in the blood of people with rheumatoid arthritis, not usually psoriatic arthr. ...Read more
Mild Psoriasis sufferer, chronic pain right forarm & elbow. Blood tests 80 titre ana, positive anticentromere. Psoriatic arthritis or scleroderma?
Occam's Razor: The simplest explanation is most the likely one. Usually Systemic Sclerosis and/or limited Scleroderma is not characterized by arthritis like you describe. The typical biomarker is anti Scl-70 (anti-topoisomerase). Symptoms have to be put into a broader context and be characterized beyond elbow and forearm pain. This one you should see a rheumatologist about. Dermatology would be useful as well. ...Read more
Friend has psoriasis on methotrexate. Labs CBC, cmp, tsh, ESR and ANA are normal. Starting to get joint pain but not red or swollen. What are chances to progress to psoriatic arthritis? Sees derm.
See your doctor.: A rheumatology referral may be necessary, but a nsaid, with sulfasalazine and Methotrexate given once weekly are my first treatments. The biologics work (enbrel, humira, (adalimumab) remicade) work, but are quite expensive, not generic, require prior authorization, and almost always require prior Methotrexate therapy. Leflunomide, azothioprine, and Cyclosporine are options, given by someone in rheumatology! ...Read more
No cure, but remitts: Few people should face significant joint issues, if this most common of rheumatic diseases was diagnosed early and treated with remitting agents once diagnosed. If you have no sx, do you have disease? ...Read more
Psoriatic arthritis: Mostly genetics and immunologic function.Get a more detailed answer ›
Depends...: ...On what you do now. Multiple treatments, ranging from oral medications to biologics like enbrel, humira, and stelara, (ustekinumab) are effective in treating psoriatic arthritis and preventing damage to joints. If you do not address the problem now, your joints will suffer damage in later life and your mobility will be compromised. See a dermatologist skilled in psoriasis treatment asap. ...Read more
Sometimes: There needs to be more research but there is evidence showing that those who drink alcohol regularly have a greater risk of psoriasis, and many who have psoriasis & psoriatic arthritis note that their symptoms flare with alcohol use and improve when they avoid it; but this likely is not true for everyone who has psoriasis. See http://www. Medpagetoday. Com/dermatology/psoriasis/23999. ...Read more
Most patients need a: Psoriatic arthritis can be a very inflammatory disease. We all want pain relief for our patients, but rheumatologists understand the need to reduce inflammation, because it portends coniued damge to joints, as well as much earlier cardiac disease. My personal favorites: sulfasalazine with methotrexate, the latter given sc. Some, albeit few, patients need tnf-alpha inhibitors. ...Read more
Why?: They are no effective naturopathic therapies. See a dermatologist instead. ...Read more
If a focal joint: I would inject the toe with stroids and make sure you were on systemic meds like mtx or sulfasalazine. In refractory cases, Humira or Enbrel (etanercept) are last resort. ...Read more
Psoriatic arthritis: Your doctor may recommend tumor necrosis factor-alpha (tnf-alpha) inhibitors if you have severe psoriatic arthritis. These drugs block the protein that causes inflammation in some types of arthritis and can improve signs and symptoms of psoriasis, as well. This group of drugs is the best to treat arthritis caused by psoriasis. ...Read more
Is it possible to be put on methotrexate treatment for psoriatic arthritis & what was the outcome?
I have severe pain on the ulnar side of my elbow. Could this be attributed to psoriatic arthritis?
Elbow pain: This could be ulnar neuropathy (cubital tunnel syndrome). Irritation/inflammation of the ulnar nerve as it passes within the cubital tunnel of the elbow can cause medial elbow pain, tingling sensations down the forearm into the hand with weakness in some muscles of the hand. Medial epicondylitis (golfer's elbow) is also a cause of 'inner elbow' or medial elbow pain. A consult with a physiatrist is. ...Read more
My leg/knee won't straighten. Have diagnosis of psoriatic arthritis but what can I do to get leg to work properly?
Need evaluation: Sometimes when the knee "locks" or cannot straighten out fully, it means that there may be a tear in the cartilage (meniscus) preventing the knee from straightening. See an orthopedist or a physiatrist (rehab medicine specialist) and he/she should be able to help you with it. ...Read more
I have 6 weekly blood tests (methotexate psoriatic arthritis) which often show elevated inflammation. Will this effect my organs?
Is it possible for someone to have psoriatic arthritis without ever having the skin condition? Specially if a parent has psoriasis?
An "ana" is a blood test used to screen a person for the possibility of several autoimmune diseases. It is important to remember that this is a screening test and a positive result only indicates more testing may be warranted. No blood test is perfect, and getting to a diagnosis is usually much more complex than drawing blood and looking at a number ...Read more
An autoimmune disease involving the skin, nails, and occasionally the joints. It is not contagious. There are several types of skin lesions, most common variety being large red scaly itchy plaques on extensor surfaces such as elbows and knees. Psoriasis can be controlled by a wide variety of medications, but a cure has ...Read more