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Doctor insights on: Psoriatic Arthritis As Connective Tissue Disease

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Can indomethacin stop the progression of disease in psoriatic arthritis?

Can indomethacin stop the progression of disease in psoriatic arthritis?

Unfortunately not: Tnf inhibitors are the main drugs that have demonstrated stopping the progression of psoriatic arthritis. ...Read more

Dr. Thomas Namey
2,357 doctors shared insights

Arthritis (Definition)

Arthritis is progressive degeneration of one or more joints. Symptoms may include joint pain, swelling, decreased motion, and stiffness. The two most common types of arthritis are osteoarthritis, which is associated first with articular cartilage breakdown with a component of inflammation, and rheumatoid arthritis, which is a systemic autoimmune disorder that affects joint linings first and secondarily ...Read more


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Is Psoriatic Arthritis in the spine very severe a disease?

Is Psoriatic Arthritis in the spine very severe a disease?

Varies : It varies tremendously based upon the severity of the arthritis. Some may have minimal symptoms, or others can have cares that are quite debilitating. I would certainly be seen by a rheumatologist as well as a spinal specialist. ...Read more

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Has any one taken the disease modifying drug (dmards) for their psoriatic arthritis?

Has any one taken the disease modifying drug (dmards) for their psoriatic arthritis?

Most patients need a: Psoriatic arthritis can be a very inflammatory disease. We all want pain relief for our patients, but rheumatologists understand the need to reduce inflammation, because it portends coniued damge to joints, as well as much earlier cardiac disease. My personal favorites: sulfasalazine with methotrexate, the latter given sc. Some, albeit few, patients need tnf-alpha inhibitors. ...Read more

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Can you tell me about taking the disease modifying drug (dmards) for their psoriatic arthritis?

Can you tell me about taking the disease modifying drug (dmards) for their psoriatic arthritis?

See details: The two major DMARDs for treating psoriatic arthritis are Methotrexate and the biologics such as Remicade, (infliximab) Enbrel and Humira among others. All are extremely effective, especially the biologics. All have potential side effects such as infection risk, reduced blood counts and liver disease. ...Read more

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Does early spinal involvement in Psoriatic Arthritis indicate more severe form of the disease with deformity?

Does early spinal involvement in Psoriatic Arthritis indicate more severe form of the disease with deformity?

No-there are 5 types: There are 5 different types of psoriatic arthritis. Back involvement is one type of these and there can be overlaps. Your rheumatologist can better advise you on the state of your risks and involvements. Many things impact this. ...Read more

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Is there a connection between psoriatic arthritis and heart disease?

Is there a connection between psoriatic arthritis and heart disease?

Yes : People with psoriasis (including psoriatic arthritis) have higher incidence of metabolic syndrome, diabetes, hyperglycemia, hypertension and obesity, all risk factors for cardiovascular disease. Atherosclerosis, presumably due to the inflammatory nature of the condition is more common in pa. There is some evidence suggesting anti-tnf therapy lowers the cardiovascular risk in patients with pa. ...Read more

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Can menopause trigger autoimmune disorders? I was diagnosed with both psoriatic arthritis and celiac disease at 51.

Can menopause trigger autoimmune disorders? I was diagnosed with both psoriatic arthritis and celiac  disease at  51.

Maybe: There is more autoimmune (AI) disease in older women, but it is unclear if it is related to time or hormones. Time: an AI condition is a problem in the immune system. The longer we live, the more likely a problem will develop. Hormones: women have an immune system that tolerates foreign things, that is how they have a baby. If that tolerance goes away, then there can be an issue. But exact cause? ...Read more

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Which disease usually has the best prognosis: 1. SLE, 2. Rheumatoid arthritis, 3. Psoriasis or 4. Psoriatic Arthritis?

Which disease usually has the best prognosis: 1. SLE, 2. Rheumatoid arthritis, 3. Psoriasis or 4. Psoriatic Arthritis?

Impossible to say: It depends on the severity of each disease. Psoriatic would be considered the most benign. ...Read more

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Father has psoriasis and psoriatic arthritis, I also have joint pain. Does that mean an autoimmune disease will pass on to my son as well?

Father has psoriasis and psoriatic arthritis, I also have joint pain. Does that mean an autoimmune disease will pass on to my son as well?

Not 100%: While your son will have an increased chance, it is not for certain he will have an autoimmune disorder. He has a different mother with different genetics as do you and your father. ...Read more

Tissue (Definition)

The body is composed of tissue that are classically described as beiing derived from three basic embyonic layers known as the endoderm, mesoderm and ectoderm that then differentiate into the structures that compose the body such as skin, soft tissues, bone, muscle, organs, etc. Stem cells are not differentiated and have the potential to ...Read more


Dr. Thomas Namey
1,001 doctors shared insights

Psoriasis (Definition)

Psoriasis is an autoimmune disease involving the skin, nails, and occasionally the joints. It is not contagious. There are several types of skin lesions, most common variety being large red scaly itchy plaques on extensor surfaces such as elbows and knees. Psoriasis can be controlled by a wide variety of medications, but a cure has ...Read more