Doctor insights on:
Psoriatic Arthritis As Connective Tissue Disease
Arthritis is progressive degeneration of one or more joints. Symptoms may include joint pain, swelling, decreased motion, and stiffness. The two most common types of arthritis are osteoarthritis, which is associated first with articular cartilage breakdown with a component of inflammation, and rheumatoid arthritis, which is a systemic autoimmune disorder that affects joint linings first and secondarily ...Read more
Most patients need a: Psoriatic arthritis can be a very inflammatory disease. We all want pain relief for our patients, but rheumatologists understand the need to reduce inflammation, because it portends coniued damge to joints, as well as much earlier cardiac disease. My personal favorites: sulfasalazine with methotrexate, the latter given sc. Some, albeit few, patients need tnf-alpha inhibitors. ...Read more
See details: The two major DMARDs for treating psoriatic arthritis are Methotrexate and the biologics such as Remicade, (infliximab) Enbrel and Humira among others. All are extremely effective, especially the biologics. All have potential side effects such as infection risk, reduced blood counts and liver disease. ...Read more
Does early spinal involvement in Psoriatic Arthritis indicate more severe form of the disease with deformity?
Yes : People with psoriasis (including psoriatic arthritis) have higher incidence of metabolic syndrome, diabetes, hyperglycemia, hypertension and obesity, all risk factors for cardiovascular disease. Atherosclerosis, presumably due to the inflammatory nature of the condition is more common in pa. There is some evidence suggesting anti-tnf therapy lowers the cardiovascular risk in patients with pa. ...Read moreSee 1 more doctor answer
Can menopause trigger autoimmune disorders? I was diagnosed with both psoriatic arthritis and celiac disease at 51.
Maybe: There is more autoimmune (AI) disease in older women, but it is unclear if it is related to time or hormones. Time: an AI condition is a problem in the immune system. The longer we live, the more likely a problem will develop. Hormones: women have an immune system that tolerates foreign things, that is how they have a baby. If that tolerance goes away, then there can be an issue. But exact cause? ...Read moreSee 1 more doctor answer
Which disease usually has the best prognosis: 1. SLE, 2. Rheumatoid arthritis, 3. Psoriasis or 4. Psoriatic Arthritis?
Impossible to say: It depends on the severity of each disease. Psoriatic would be considered the most benign. ...Read more
Father has psoriasis and psoriatic arthritis, I also have joint pain. Does that mean an autoimmune disease will pass on to my son as well?
Not 100%: While your son will have an increased chance, it is not for certain he will have an autoimmune disorder. He has a different mother with different genetics as do you and your father. ...Read more
The body is composed of tissue that are classically described as beiing derived from three basic embyonic layers known as the endoderm, mesoderm and ectoderm that then differentiate into the structures that compose the body such as skin, soft tissues, bone, muscle, organs, etc. Stem cells are not differentiated and have the potential to ...Read more
Psoriasis is an autoimmune disease involving the skin, nails, and occasionally the joints. It is not contagious. There are several types of skin lesions, most common variety being large red scaly itchy plaques on extensor surfaces such as elbows and knees. Psoriasis can be controlled by a wide variety of medications, but a cure has ...Read more
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