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Doctor insights on: Pseudohypoparathyroidism

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Dr. Louis Gallia
6 doctors shared insights

Pseudohypoparathyroidism (Overview)

A condition associated primarily with resistance to the parathyroid hormone.


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I believe I have pseudohypoparathyroidism, does this need to be treated?

I believe I have pseudohypoparathyroidism, does this need to be treated?

Interesting!: Hi. That's a rare genetic disease! See an endocrinologist. Since pseudohypoparathyroidism presents with low serum calcium and calcitriol (the active form of vitamin D), these usually need to be replaced (serum calcium to the LOW end of normal so you don't lose too much calcium in the urine and get kidney stones). If you are right and you have it, you'll thrill some endocrinologist! All the best. ...Read more

Dr. Louis Gallia
6 doctors shared insights

Pseudohypoparathyroidism (Overview)

A condition associated primarily with resistance to the parathyroid hormone.


2

2
What do you suggest if my symptoms are similar to those presented in a case of pseudohypoparathyroidism. how can I be sure?

What do you suggest if my symptoms are similar to those presented in a case of pseudohypoparathyroidism. how can I be sure?

Measure PTH: Hi. It's quite easy, really. Document low blood calcium, high blood phosphate, and high PTH in a patient who is short and has short fingers & toes, etc. It can tested for provocatively by injecting PTH (or teriparatide) and measuring urinary cyclic AMP. See an endocrinologist with an interest in calcium metabolism. Good luck! ...Read more

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What is pseudohypoparathyroidism? What are the symptoms?

What is pseudohypoparathyroidism? What are the symptoms?

Resistance to PTH: Pseudohypoparathyroidism is a rare condition which results in resistance to the effect of parathyroid hormone. Hypocalcemia develops and causes tingling and muscle cramps and, rarely, seizures. ...Read more

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I believe I have pseudohypoparathyroidism, does this need to be treated?

Interesting!: Hi. That's a rare genetic disease! See an endocrinologist. Since pseudohypoparathyroidism presents with low serum calcium and calcitriol (the active form of vitamin D), these usually need to be replaced (serum calcium to the LOW end of normal so you don't lose too much calcium in the urine and get kidney stones). If you are right and you have it, you'll thrill some endocrinologist! All the best. ...Read more

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My symptoms resemble pseudohypoparathyroidism. How can I be sure this is what I have?

My symptoms resemble pseudohypoparathyroidism. How can I be sure this is what I have?

Test PTH and calcium: Hi. Pseudohypoparathyroidism (PHP) is an uncommon genetic defect with faulty PTH receptor signaling. You should see an endocrinologist for exam (there may be characteristic physical exam findings) and measurement of calcium, phosphate, calcitriol, and PTH. In hypopara, PTH is low and calcium is low. In PHP, calcium is low and PTH is elevated. Good luck. ...Read more

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What do you suggest if my symptoms are similar to those presented in a case of pseudohypoparathyroidism. how can I be sure?

Measure PTH: Hi. It's quite easy, really. Document low blood calcium, high blood phosphate, and high PTH in a patient who is short and has short fingers & toes, etc. It can tested for provocatively by injecting PTH (or teriparatide) and measuring urinary cyclic AMP. See an endocrinologist with an interest in calcium metabolism. Good luck! ...Read more

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Can unexplained brittle fingernails be caused by pseudohypoparathyroidism?

Can unexplained brittle fingernails be caused by pseudohypoparathyroidism?

Fingernails: I don't think so. I hope you are seeing an Endocrinologist for your pseudo hyperpara. If not you must do so and ask about your nails. ...Read more

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Any association between Pseudohypoparathyroidism and Malignant Hyperthermia?

Any association between Pseudohypoparathyroidism and Malignant Hyperthermia?

Should not be...: Pseudohypoparathyroidism (PHP) is a disorder of calcium sensing in the kidneys and bone (mult types) & leads to calcium wasting by the the kidneys. However, the possible genetic issues affect a protein that is found throughout the body and can lead to multiple endocrine probs and symptoms. Random fact about PHP is the same gene prob causes diff symptoms if inherited from mother or father. ...Read more

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Pseudohypoparathyroidism? I have "archibald's sign," chronic skin rash, constipation, heart flutter. Come home asap from vet school abroad for dx/tx?

Pseudohypoparathyroidism? I have "archibald's sign," chronic skin rash, constipation, heart flutter. Come home asap from vet school abroad for dx/tx?

Pseudohypopara: You present a number of medical complaints, all of which need attention. Please start with a visit to your primary doctor. Your medical history will be taken, you will be examined by the doctor, and laboratory studies will be ordered. Once the information is collected your doctor will decide where you might go for further care. Please let me know what develops. ...Read more

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If Dr. (endocrinology) can get me in by end of yr, I'll fly to u. Believe to have pseudohypoparathyroidism. Dealing w/ sv muscle pain in legs, seizures, fit body type, labs fit (Calcium, Phosphorous, Albumin). Will allow study. Chelseakaymg@gmail.com?

What are you doing?: First, are you sure this is the diagnosis? What labs have you had done & results? Are you on any treatment? This needs to be discussed more a diagnosis made and treatment may need to be started now. With a little more information some treatment should also be able to be started. This is also a life long disease and will need ongoing endo f/u. We should be able to get you in to one near home ...Read more