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Doctor insights on: Pseudoephedrine And Prozac Interactions

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I have VERY bad sinus problems. Is it okay to take Sudafed and Benadryl (diphenhydramine) together? I also take birth control and fluoxetine for prescriptions. Thanks!

I have VERY bad sinus problems. Is it okay to take Sudafed and Benadryl (diphenhydramine) together? I also take birth control and fluoxetine for prescriptions. Thanks!

Short term: You may take Sudafed and Benadryl (diphenhydramine) together for sinus congestion. The recommended dose of Sudafed in 30 mg three times a day for 5 days. You can take up to 50 mg of Benadryl (diphenhydramine) at a time, but it is likely to make you tired. There are no major interactions with your birth control and fluoxetine. As always, consult with your doctor if you have ongoing problems. ...Read more

Dr. Heidi Fowler
1,057 Doctors shared insights

Fluoxetine (Definition)

Fluoxetine (brand prozac) is an antidepressant in the class known as serotonin selective reuptake inhibitors aka ssris. Fda approved in 1987 for the treatment of major depressive disorder. Subsequently approved for obsessive compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder. Significantly safer and much better ...Read more


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What are the interactions between Prozac (fluoxetine) and adipex?

What are the interactions between Prozac (fluoxetine) and adipex?

Do not combine: IF you look at the FDA approved prescribing information for adipex, it clearly warns against combining the two due to serotonin syndrome risk (abnormal jerks, increased reflexes, temperature, confusion, sweating, elevated heart rate and BP, seizure risk). Prozac (fluoxetine) also blocks an enzyme that many medicines rely on for their own metabolism and can sometimes affect blood levels that way. ...Read more

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I take 30mg Prozac and 5mg Valium daily. Is it ok to use CBD (Cannabidiol) to help get off Valium? Any interactions?

I take 30mg Prozac and 5mg Valium daily. Is it ok to use CBD (Cannabidiol) to help get off Valium? Any interactions?

No: Is illegal in some states and is only medicinal in some states and recreational in few states. Consult with your psychiatrist for help getting off Valium ...Read more

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Is it ok to take siberian ginseng daily for people who are stressed. Are there any major interactions with ssris like prozac (fluoxetine)?

Is it ok to take siberian ginseng daily for people who are stressed. Are there any major interactions with ssris like prozac (fluoxetine)?

Could be some: I checked naturaldatabase. Com -- which says that siberian ginseng may inhibit both cytochrome p450 2d6 as well as 2d9. Prozac (fluoxetine) is metabolized by these same enzymes, so its metabolism could take longer, and build up in your system. These are potential interactions only, but you asked. Rhodiola rosea is another adaptogenic herb that may help depression. It has no interactions at all with prozac (fluoxetine). ...Read more

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Are there any interactions between chicory root and prozac (fluoxetine). I heard that chicory is a good coffee alternative and I would like to try it. Thanks?

Are there any interactions between chicory root and prozac (fluoxetine). I heard that chicory is a good coffee alternative and I would like to try it. Thanks?

Coffee substitute: Chicory root appears to have no known adverse interactions with any drugs. It may cause skin, respiratory, or intestinal allergies and it may induce uterine contractions...therefore it is not recommended in pregnancy. So if you are not pregnant or allergic to it, taking it with Prozac (fluoxetine) may be OK. ...Read more

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My dr just took me off 70 mg of Vyvanse (lisdexamfetamine) and started me on prozac. How long do I need to wait before taking the Prozac to avoid a possible interaction?

Depends: If these are the only medications you are on, then there is no need to impose a wait time between starting Prozac after stopping vyvanse (lisdexamfetamine). These medications are often prescribed concurrently. Prozac (fluoxetine) is considerable potential for interactions with a variety of medications. As such, ensure that your prescribers know that you are taking it to minimize potential interactions. ...Read more

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Is there an interaction with taking Prozac (fluoxetine) and sinimet?

Is there an interaction with taking Prozac (fluoxetine) and sinimet?

Probably OK: Prozac (fluoxetine) is a mood/depression medication that works on serotonin. Sinemet is a medicine most commonly used for parkinson disease that works primarily on dopamine. There are always possible interactions from two medications, but these two are used together in many patients without problems. ...Read more

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Are there any interactions between roseroot (rhodiola rosea) and prozac (fluoxetine)? Thank you for your time.

Are there any interactions between roseroot (rhodiola rosea) and prozac (fluoxetine)? Thank you for your time.

Unknown: There is limited information on roseroot. There is anecdotal evidence from russia that it improves mood. There are animal studies which show it works similar to anti-depressants called maoi. The active ingredients are unknown but appear to be polyphenols which are relatively harmless. I would take all herbal supplements cautiously as the interactions with medications are not well established. ...Read more

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Are there any interactions between turmeric (tea) and prozac (fluoxetine)?

Are there any interactions between turmeric (tea) and prozac (fluoxetine)?

None known: I do not know of any interactions between turmeric and prozac (fluoxetine). However, no known interactions does not mean that none are possible. ...Read more

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Is it safe to take moringa oleifera along with prozac (fluoxetine)? Are there any possible interactions?

Is it safe to take moringa oleifera along with prozac (fluoxetine)? Are there any possible interactions?

I have checked a #: Of drug interaction reporting sites and have found no reports of drug interactions between these two compounds a far. Cytochrome p450 substrates, including cyp3a4: moringa oleifera inhibits cyp-450 / cyp3a4. It can increase the bioavailability of Rifampin and may interact with other drugs metabolized by cyp3a4.
Prozac does not utilize this system. Best wishes. ...Read more

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Is it ok to drink dandelion root tea while on Prozac (fluoxetine) 40mg/day? Are there any interactions? Thanks

Not much interaction: The extract of taraxicum officinale root in rodent studies is shown to be an inhibitor of the cytochrome p450 1a2 enzyme, and this is distinct from the 2d6 enzyme that fluoxetine inhibits. This would imply that the consuming dandelion root extract would not markedly change the metabolism of fluoxetine although it may slow down the metabolism of fluoxetine very slightly because 1a2 may contribute. ...Read more

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Are there any interactions between Inositol and Prozac (fluoxetine) or Clonazepam?

Probably not but. ..: Always check with your prescribing MD, who is most familiar with your illness and symptoms, about adding any new supplements to determine if this is the right tx for you :). Good luck! ...Read more

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Can I take zofran (ondansetron) for nausea if I take 10mg prozac once a day? Are there any interactions?

Can I take zofran (ondansetron) for nausea if I take 10mg prozac once a day? Are there any interactions?

Probably ok: Sometimes there is an interaction, but generally, these can be safely used together.

Zofran can cause sleepiness, this is the primary side effect to be aware of. ...Read more

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Can you take Prozac (fluoxetine) and Flagyl together or will there bea bad interaction? I have BV and need to take flagyl?

Can you take Prozac (fluoxetine) and Flagyl together or will there bea bad interaction? I have BV and need to take flagyl?

Med interactions: I just checked this on a drug interaction checker & it showed no problems. However I would think it might slightly increase the chances for an upset stomach. Take care. ...Read more

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Is butterbur safe for migraines? Interactions? Taking Prozac (fluoxetine) to incr. Serotonin to reduce headaches. On a lot of other meds.

Is butterbur safe for migraines? Interactions? Taking Prozac (fluoxetine) to incr. Serotonin to reduce headaches. On a lot of other meds.

Generally safe: Although butterbur is generally safe (and probably safer than most medications used to treat migraine), there have been some reports of liver toxicity in some preparations. Look for preparations that are low in pyrrolizidine alkaloids (pas), which is thought to be the ingredient that can cause toxicity. ...Read more

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My dr said it was ok to take Imitrex (sumatriptan) while on Prozac despite the major interaction listed. Now maxalt also has the same interaction. Is it safe?

Serotonin syndrome: A limited number of people have had a serotonin syndrome from the combination of triptan migraine meds like imitrex, (sumatriptan) Maxalt with ssris like Prozac but I'm had many patients safely take the combo. Because the migraine meds are short acting I've not seen problems. What's for serotonin syndrome sx of sweating, confusion, agitation, racing heart rate. You might best start with half doses. ...Read more

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Is there a doctor in here who has lived. With someone on prozac (fluoxetine)? If so how did it affect the relationship, the interaction between, the closeness, ?

Is there a doctor in here who has lived. With someone on prozac (fluoxetine)? If so how did it affect the relationship, the interaction between, the closeness, ?

Yes: If Prozac (fluoxetine) works well it often reduces anxiety, depression and irritsability making closeness easier. It also can have a significant effect on sexual function, with decreased sexual interest and difficulty with arousability with might easily impair intimate closeness. In addition some people have a negative effect with increased irritability clearly impairing closeness. ...Read more

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Prescribed 18mg of Strattera (atomoxetine) for focus. On Prozac (45mg) and Propranolol (10mg 3x/day). Interactions? Side effects? I've read some troubling reviews.

Prescribed 18mg of Strattera (atomoxetine) for focus. On Prozac (45mg) and Propranolol (10mg 3x/day). Interactions? Side effects? I've read some troubling reviews.

Probably ok: That dose of Straterra is pretty low. Many patients are on this medication along with an SSRI. Let your doctor know if you experience any strange side effects ...Read more

Dr. Suhas Pai Dr. Pai
1 doctor agreed:
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Are the any interactions between milk thistle and Prozac (fluoxetine) and/or clonazepam?

Dr. Suhas Pai Dr. Pai
1 doctor agreed:

Yes: There is some research that shows that milk thistle can slow activity of certain enzymes in the liver that help the body to metabolize drugs. If the enzymes are inhibited by the milk thistle, then the level of the drugs will be higher. Prozac (fluoxetine) is one such drug. Clonazepam levels can be reduced if taken with milk thistle. ...Read more

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Can Prozac (fluoxetine) and the eye medicine timolo be taken together without a interaction problem?

Can Prozac (fluoxetine) and the eye medicine timolo be taken together without a interaction problem?

In general fine: But you are in an age group, where folks get to be sensitive to anticholinergic effects of these two medicines, and it can be subtly additive. So, if you feel your memory, focus, concentration is not quite right, notify your doctor about this, as that is where issues might arise. ...Read more

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Please tell me if there are any serious interactions when prozac, Pliva 333, birth control, ritalin (methylphenidate) are all taken together?

Please tell me if there are any serious interactions when prozac, Pliva 333, birth control, ritalin (methylphenidate) are all taken together?

Check w/ prescriber!: Prozac (fluoxetine), Pliva 333 (metronidazole), ritalin (methylphenidate) (a stimulant), and birth control are all commonly prescribed meds. Doses? Indications? Routes? Form of birth control? Always provide an updated list of ur meds to each of your docs/prescribers. Contact ur prescribers ASAP to learn about any possible drug-drug interactions! Use condoms until ur certain no interaction w BC. Be well! ...Read more

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I'm on Prozac (fluoxetine) have been for many years started taking garcinia cambogia and now I'm having face numbness. Can this be an interaction?

I'm on Prozac (fluoxetine) have been for many years started taking garcinia cambogia and now I'm having face numbness. Can this be an interaction?

Garcinia cambogia: There is little available information regarding garcinia cambogia and various medications. However it would make sense to stop it. I'd also get evaluated to make sure there are no other medical issues at hand. Please note that this herbal isn't a proven weight loss remedy despite it being widely promoted as such. ...Read more

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Are there any interactions between 50mcg levothyroxine and 20mg Prozac (fluoxetine)? Can I take Prozac (fluoxetine) 1 hr after thyroid? I just did, is it safe?

Prozac (fluoxetine): If your doctor knows that you are taking levothyroxine and still prescribes Prozac (fluoxetine) please follow that advice.

Of course if you feel a change in the wrong direction stop taking it and call your doctor. ...Read more

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Is it ok to take Albuterol as needed while I take Prozac (fluoxetine)? I saw on the drug interaction checker this can cause arrythmias? I have bad asthma.

Is it ok to take Albuterol as needed while I take Prozac (fluoxetine)? I saw on the drug interaction checker this can cause arrythmias? I have bad asthma.

Yes: If you need albuterol for rescue treatment don't avoid it because you are taking Prozac (fluoxetine). If you are requiring albuterol frequently make an appointment with primary doctor so that you can get your asthma worked up, sounds like you are poorly controlled. You might need to step up therapy with controller meds. Good luck. ...Read more

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I take 10 mg of prozac (fluoxetine) a day. I get bad headaches from it. Am I allowed to take ibuprofen for the headaches? Are there any interactions btwn the two?

I take 10 mg of prozac (fluoxetine) a day. I get bad headaches from it. Am I allowed to take ibuprofen for the headaches? Are there any interactions btwn the two?

Ask your doctor: You should ask your doctor for the clearance to take other medications (even over the counters) while on Prozac (fluoxetine). Well, actually interesting you should ask because in fact, there are significant interactions which can cause either an increase in bleeding complications due to the ibuprofen or increased toxicity of the Prozac (fluoxetine). The combination should be closely monitored in general. Check with Doctor ...Read more

Dr. Louis Vernacchio
405 Doctors shared insights

Pseudoephedrine (Definition)

Pseudoephedrine is a decongestant which is a kind of antihistamine type drug (common ...Read more


Dr. Alan Ali
778 Doctors shared insights

Prozac (Definition)

Prozac is a serotonin reuptake blocker which is a kind of ...Read more