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Doctor insights on: Prozac Fatigue

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TSH 3 & PCOS. Took metformin for 2 yrs then stopped. Now on Synthroid (thyroxine) 50mcg & Prozac 20mg. Still tired, fatigue. Any supplementation?

TSH 3 & PCOS. Took metformin for 2 yrs then stopped. Now on Synthroid (thyroxine) 50mcg & Prozac 20mg. Still tired, fatigue. Any supplementation?

With normal TSH fatigue is nonspecific.: Although the TSH level is in the upper mid range of normal, your dose could be slightly adjusted upward to for example 75 µg daily. Your fatigue could be secondary to underlying depression for which you are taking medication for. Metformin is commonly used in PCOS for normalizing periods and ovulation. Have your vitamin D levels checked. ...Read more

Dr. Heidi Fowler
1,057 doctors shared insights

Fluoxetine (Definition)

Fluoxetine (brand prozac) is an antidepressant in the class known as serotonin selective reuptake inhibitors aka ssris. Fda approved in 1987 for the treatment of major depressive disorder. Subsequently approved for obsessive compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder. Significantly safer and much better ...Read more


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I've been on Prozac (fluoxetine) for years, 20 & now 40 mg. I've been off for about a month. I feel great, except for fatigue. Is the drug still active?

I've been on Prozac (fluoxetine) for years, 20 & now 40 mg.  I've been off for about a month. I feel great, except for fatigue.  Is the drug still active?

NO: That's GREAT...you are clear of the drug and probably do not need it for now! Make sure you report ANY change in your present Mood etc to your Doctor!

Good Luck
Hope this Helps!
Dr Z ...Read more

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I'm weening off 30mg of Prozac (fluoxetine) after being on it for a year, is it normal to have physical withdrawal symptoms, such as severe fatigue?

I'm weening off 30mg of Prozac (fluoxetine) after being on it for a year, is it normal to have physical withdrawal symptoms, such as severe fatigue?

Can happen: SSRI discontinuation syndrome symptoms may include: flu-like sx’s, insomnia, nightmares, vivid dreams, anxiety, tearfulness, depressed mood, confusion, irritability, restless legs, tremors, nausea, vomiting, cramps, loose stools, loss of appetite, dizziness, unsteady gait, flushing, sweating, headache, lethargy, imbalance, vertigo, ringing in ears, hypersensitivity to noise, sensation of ...Read more

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I am on Prozac (fluoxetine) 20 mg for anxiety disorder. Since a while I am feeling fatigue etc but mood ok. Does this mean my dose of Prozac (fluoxetine) needs adjustment?

I am on Prozac (fluoxetine) 20 mg for anxiety disorder. Since a while I am feeling fatigue etc but mood ok. Does this mean my dose of Prozac (fluoxetine) needs adjustment?

Prozac (fluoxetine) : I am happy your moods are better and probably the Prozac (fluoxetine) has helped you. The fatigue can be from multiple causes. I doubt the Prozac (fluoxetine) needs adjustment but it is true that raising the dose could help but only with your doctors agreement. ...Read more

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How does Prozac (fluoxetine) help with chronic fatigue syndrome?

How does Prozac (fluoxetine) help with chronic fatigue syndrome?

Prozac (fluoxetine): Mechanism still unknown. One theory is elevation of serotonin in brain which modulated energy level. ...Read more

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How much can Prozac (fluoxetine) help with chronic fatigue syndrome?

How much can Prozac (fluoxetine) help with chronic fatigue syndrome?

Sometimes none : Prozac (fluoxetine) has a variable benefit in cfs. In my experience, it can be tried but there are other meds which are generally more helpful. ...Read more

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I have been fatigued for 2 months dr reduced Paxil (paroxetine) dose from 60mg to 40mg with one 20mg fluoxitene for 1 month anxiety and low moods stopped Prozac 20mg and went back to 60mg Paxil (paroxetine) dose. Wat do I do?

I have been fatigued for 2 months dr reduced Paxil (paroxetine) dose from 60mg to 40mg with one 20mg fluoxitene for 1 month anxiety and low moods stopped Prozac 20mg and went back to 60mg Paxil (paroxetine) dose. Wat do I do?

Medications: It looks like you're also on seroquel and Klonopin as well as zopiclone -- all of which can increase fatigue. Plus on concerta? Your doctor may be trying to help your depression, and Prozac did not help as hoped. Perhaps the 2 of you need a serious talk about all your medications and their results -- not just Paxil (paroxetine) and prozac. If not seeing a psychiatrist, it's time for a consult. Best wishes. ...Read more

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My doctor prescribed me methylcobalamin injections after every 2 weeks to counter some fatigue or energy side effects of prozac (fluoxetine). Is this any help?

My doctor prescribed me methylcobalamin injections after every 2 weeks to counter some fatigue or energy side effects of prozac (fluoxetine). Is this any help?

Probably not: Methylcobalamin is a form of vitamin b12. It is useful for treating vitamin B12 deficiency, which can cause fatigue symptoms. However, there are many other causes of fatigue and low energy, including depression (is that why you're taking prozac (fluoxetine)?). Prozac (fluoxetine) itself may cause fatigue and low energy, although it usually doesn't. Methylcobalamin probably won't help that. ...Read more

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With Prozac (fluoxetine) for 1w. Dizziness headaches extreme fatigue, itchiness in various spots. (thought was mosquitoes, but no bites) normal side effects?

With Prozac (fluoxetine) for 1w. Dizziness headaches extreme fatigue, itchiness in various spots. (thought was mosquitoes, but no bites) normal side effects?

Some are: If symptoms get worse stop the med. Usual side effects get less than your body adjusts to the medicine. So things should get better. If they don't. Stop the meds and talk to your doctor about alternatives. ...Read more

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I am currently taking Prozac 20 mg and have been experiencing these side effects: I am currently taking Prozac 20 mg and have been experiencing these side effects: dizziness, weakness, weight gain, confusion, memory loss, and lately I'm always fatigued. I

I am currently taking Prozac 20 mg and have been experiencing these side effects: I am currently taking Prozac 20 mg and have been experiencing these side effects: dizziness, weakness, weight gain, confusion, memory loss, and lately I'm always fatigued. I

Possibly: I agree with dr. Wynn. I will add that it may also depend on how long you've been on this medicine. If it is a med that you recently started, then these side effects can be common. Often times the side effects can lessen or go away with time. ...Read more

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What is better for anxiety, depression, fatigue, and insomnia? Prozac, remeron, (mirtazapine) or celexa? Or maybe other?

What is better for anxiety, depression, fatigue, and insomnia? Prozac, remeron, (mirtazapine) or celexa? Or maybe other?

Depends on person: All the medications you mention can be highly effective. It can take a while to find the one that has the best benefit with the fewest side effects. At present, it's trial and error. We have no tests to match person to best antidepressant--although that is an area under active study. ...Read more

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Can anxiety randomly cause dizziness, head pressure and random onset fatigue? Will taking Prozac (fluoxetine) potentially help treat this issue? Brain MRI was ok.

Can anxiety randomly cause dizziness, head pressure and random onset fatigue?  Will taking Prozac (fluoxetine) potentially help treat this issue? Brain MRI was ok.

Yes it should: So glad to hear that brain MRI was ok. Yes, Prozac (fluoxetine) is prescribed for people who have anxiety and the symptoms you have reported are anxiety related. It should start relieving symptoms within two weeks with maximum effect in 4-6 weeks. Psychotherapy also will help to learn to manage anxiety triggers. ...Read more

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What antidepression do you recommend for energy if have hep c/ I've tried zoloft, prozac, celexia and Effexor (venlafaxine) but had bad side effects. Fatigue is bad?

What antidepression do you recommend for energy if have hep c/ I've tried zoloft, prozac, celexia and Effexor (venlafaxine) but had bad side effects. Fatigue is bad?

Discuss w your: Psychiatrist. If you have atypical depressive symptoms then wellbutrin (bupropion) can have favorable results. I see Methadone listed for meds ; hepatitis c listed for conditions. Do you actually have diagnosed major depression? ...Read more

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I feel fatigue and muscle weakness. Mood is ok but doc prescribed prozac (fluoxetine). Had weaned off Prozac (fluoxetine) a yr ago after treating depression and OCD type anxiety?

I feel fatigue and muscle weakness. Mood is ok but doc prescribed prozac (fluoxetine). Had weaned off Prozac (fluoxetine) a yr ago after treating depression and OCD type anxiety?

Needs evaluation: Cant say from the info provided that your past problems are your current problems, though you may have a preoccupation with illness until you are proven to be well your complaints should be taken seriously and worked up by a doctor. ...Read more

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What is Prozac (fluoxetine)?

SSRI antidepresant : It's been around a while now, but pretty revolutionary when it first came out. It is a selective serotonin reuptake inhibitor most commonly used to treat depression. The ssris were a big step forward due to far less side effects than the tricyclic antidepressants that were the main treatment for depression prior to that. ...Read more

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What is Prozac (fluoxetine) for and what are its effects?

What is Prozac (fluoxetine) for and what are its effects?

Prozac (fluoxetine): Prozac (fluoxetine) is a ssri medication which can be used to treat depression, anxiety disorders, some premenstrual disorders, and bulimia nervosa (an eating disorder). It inhibits neurons' reuptake of serotonin, so that more remains available in neuronal synapses. Common side effects include nausea, diarrhea, dizziness, drowsiness, sweating, and yawning. There can also be changes in sexual functioning. ...Read more

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Wondering why would someone be on 10mg prozac (fluoxetine)?

Wondering why would someone be on 10mg prozac (fluoxetine)?

Several reasons: While 20 mg daily is the usual adult dose, here are several reasons why someone could be on less: 1. Old (>65), young (. ...Read more

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Does Prozac (fluoxetine) help anxiety?

Does Prozac (fluoxetine) help anxiety?

In addition to or: As an alternative, consider practicing the Relaxation Response, from a book by Herbert Benson. See this website http://www.relaxationresponse.org/ Peace and good health. ...Read more

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Does Prozac (fluoxetine) lower libido?

Does Prozac (fluoxetine) lower libido?

All medications: That raise serotonin can lower libido. There are some ways to treat this side effect. Talk with your doctor about this. He can help. ...Read more

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Does Prozac (fluoxetine) help tremors?

Depends on cause: If the cause of the tremors is anxiety then the answer is it may. However, the Clonazepam may as well. I would discuss with you doctor your diagnoses and if you are on the correct doses of both medications. Also, have medical causes of you symptoms been ruled out like thyroid problems, and neurologic. Have you seen a neurologist off all medications so a good baseline can be established? ...Read more

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Can Prozac (fluoxetine) cause memory loss?

Can Prozac (fluoxetine) cause memory loss?

Do not see: Memory loss listed under side effect profile. However, sometimes a person may become less focused on Prozac (fluoxetine). If that were the case, one might not lay down new memory as well. ...Read more

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Is it safe to take ashwaganda with prozac?

Ashwaganda: Ashwaganda usually well tolerated and shouldn't cause a problem with the Prozac. Examine.com recommends that it may help. Highly recommend that you try to find a naturopathic doctor OR search for a medical professional knowledgeable about "complimentary and alternative medicine" (search those specific terms) and get them to review your situation. ...Read more

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Can prozac (fluoxetine) contribute to PVCs?

Not really: You can have a Holter monitor done on you for 12 hrs up to 30 days to determine the frequency of your PVCs if any. Different PVCs are treated differently so make sure you're seen by a knowledgable cardiologist. ...Read more

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Is serzone or Prozac (fluoxetine) is better?

They r different: Serzone isn't available was associated with liver priblems. ...Read more

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Can pregnant women take Prozac (fluoxetine)?

Can pregnant women take Prozac (fluoxetine)?

Prozac (fluoxetine): It is category C pregnancy drug, hence benefits have to outweigh risks, & the patient is closely monitored throughout pregnancy. ...Read more

Dr. Alan Ali
778 doctors shared insights

Prozac (Definition)

Prozac is a serotonin reuptake blocker which is a kind of ...Read more