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Doctor insights on: Prozac And Headaches

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Dr. Heidi Fowler
1,053 Doctors shared insights

Fluoxetine (Definition)

Fluoxetine (brand prozac) is an antidepressant in the class known as serotonin selective reuptake inhibitors aka ssris. Fda approved in 1987 for the treatment of major depressive disorder. Subsequently approved for obsessive compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder. Significantly safer and much better ...Read more


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Prozac (fluoxetine) 40mg for headaches, back pain. Wanted to try stepping back down to 20mg. Dr. Wants to keep me at 40mg. Odd that doctor doesn't want to reduce?

Prozac (fluoxetine) 40mg for headaches, back pain. Wanted to try stepping back down to 20mg. Dr. Wants to keep me at 40mg. Odd that doctor doesn't want to reduce?

Not really: I am not aware of any evidence that Prozac provides a benefit for pain. A class of medications called snri's is likely a better choice. Cymbalta (duloxetine) is now fda approved for musculoskeletal pain and it may be a better option. You should discuss this with your physician. ...Read more

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Help plz! Can Prozac (fluoxetine) cause chronic, constant headaches? What can I do for this?

Help plz! Can Prozac (fluoxetine) cause chronic, constant headaches? What can I do for this?

A possible effect: Prozac (fluoxetine) can cause headaches. If you have chronic/constant headaches you should call your prescribing doctor today and explain your symptoms. It may not be the Prozac (fluoxetine), but the symptoms, if you don't have a history of migraine headaches are cause for a call to the dr. ...Read more

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With Prozac (fluoxetine) for 1w. Dizziness headaches extreme fatigue, itchiness in various spots. (thought was mosquitoes, but no bites) normal side effects?

With Prozac (fluoxetine) for 1w. Dizziness headaches extreme fatigue, itchiness in various spots. (thought was mosquitoes, but no bites) normal side effects?

Some are: If symptoms get worse stop the med. Usual side effects get less as your body adjusts to the medicine. So things should get better. If they don't. Stop the meds and talk to your doctor about alternatives. ...Read more

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If your seratonin low cn it cause u 2 hv band headaches & all kinds of horrible symptoms 2 your body. I use to be on Prozac (fluoxetine) 25 mg & now off of it.

If your seratonin low cn it cause u 2 hv band headaches & all kinds of horrible symptoms 2 your body. I use to be on Prozac (fluoxetine) 25 mg & now off of it.

In roundabout way: If you were on Prozac (fluoxetine) and stopped, it's possible to have some uncomfortable discontinuation symptoms [including headaches] even though Prozac (fluoxetine) is less likely than other ssri's to cause these. Another possibility is that Prozac (fluoxetine) was helping you relax, including the muscles around your scalp & forehead, which can tighten into tension headaches. Serotonin doesn't necessarily need to be "low" for this. ...Read more

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I'm on Prozac (fluoxetine) 20 mg once a day for just a week now getting really bad headache with it thst won't go away with pain killers us it normal?

I'm on Prozac (fluoxetine) 20 mg once a day for just a week now getting really bad headache with it thst won't go away with pain killers us it normal?

Maybe: Headaches are one of the common side effects of Prozac (fluoxetine). Discuss this with your doctor who may want to adjust or change your medication. ...Read more

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Is butterbur safe for migraines? Interactions? Taking Prozac (fluoxetine) to incr. Serotonin to reduce headaches. On a lot of other meds.

Is butterbur safe for migraines? Interactions? Taking Prozac (fluoxetine) to incr. Serotonin to reduce headaches. On a lot of other meds.

Generally safe: Although butterbur is generally safe (and probably safer than most medications used to treat migraine), there have been some reports of liver toxicity in some preparations. Look for preparations that are low in pyrrolizidine alkaloids (pas), which is thought to be the ingredient that can cause toxicity. ...Read more

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Took 650 aspirin for headache along with normal regimine of baby aspirin and 40 Prozac (fluoxetine)...is this to much?

Took 650 aspirin for headache along with normal regimine of baby aspirin and 40 Prozac (fluoxetine)...is this to much?

No: If you take a regular dose of aspirin you do not need to take "baby aspirin" that day, however the two combined are still not too much. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco or alcohol in any form.
Practice safe sex. ...Read more

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Prozac (fluoxetine) 10mg/day in the morning for 2years. No sex drive and lately can't sleep at all. Plus headaches. Help?

Prozac (fluoxetine) 10mg/day in the morning for 2years. No sex drive and lately can't sleep at all. Plus headaches. Help?

A few possibilities: You didn't say why you're taking prozac (fluoxetine), (fluoxetine) but insomnia, no sex drive, & headaches could be depression (returning?). Since many people need 20 mg, perhaps your dose is low. These symptoms could also be Prozac (fluoxetine) side-effects, less likely if they arose suddenly 2 years after starting treatment. Or they may be completely unrelated to prozac (fluoxetine). It's best to ask your prescribing doctor about this. ...Read more

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Can I take pain killers for a headache if I just took my Wellbutrin (bupropion) and Prozac doses an hour ago? Or should I wait?

Can I take pain killers for a headache if I just took my Wellbutrin (bupropion) and Prozac doses an hour ago? Or should I wait?

Yes, you can: After neuroimaging and physical examination have excluded structural damage of the brain, headache management depends upon the particular type of headache that is present. Then you can take your pain killer immediately to break the headache ASAP. See your PCP for more information. ...Read more

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Why am I more talkative before I take my prozac (fluoxetine)? Does Prozac (fluoxetine) help nerve pain, osteoarthritis, torn disc? Does seem to reduce headaches.

Why am I more talkative before I take my prozac (fluoxetine)? Does Prozac (fluoxetine) help nerve pain, osteoarthritis, torn disc? Does seem to reduce headaches.

Not for pain per se.: I agree with dr rodrigues that prozac, (fluoxetine) and especially it's metabolite, has a long half-life, so being more talkative before you take the it should have very little to do with any major fluctuation in blood level. Perhaps it has to do with the time of day rather than the prozac, (fluoxetine) or it could be psychological? In terms of pain the literature suggests snri > ssris like Prozac (fluoxetine) in diminishing pain. ...Read more

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I've been on Prozac (fluoxetine) for 8 weeks. I had a bad headache that ended after a couple days. The past 3 weeks I've had a sinus headache. Could it be Prozac (fluoxetine)?

I've been on Prozac (fluoxetine) for 8 weeks. I had a bad headache that ended after a couple days. The past 3 weeks I've had a sinus headache. Could it be Prozac (fluoxetine)?

Yes, or it could be: A separate condition (s). An EENT MD can quickly figure out if you have sinus conditions and if they caused your headaches. If so, treat that first. But, SSRI's are known to cause lots of side effects, including the ones you have. If nothing else pans, go to your prescribing MD (for the Prozac) and ask if another med might do. Don't necessarily stop on your own first, unless too uncomfort ...Read more

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Switched from Prozac (fluoxetine) 2 brupropion 75mg 2xpd having dull headache and sore calfs an thighs. Is this normal and how long should I try 4?

Change: Talk to your doctor when ever switching medications there are some side effects which gradually go away headache and tachycardia is one of side effects best is to start low and go slow. ...Read more

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I take 10 mg of prozac (fluoxetine) a day. I get bad headaches from it. Am I allowed to take ibuprofen for the headaches? Are there any interactions btwn the two?

I take 10 mg of prozac (fluoxetine) a day. I get bad headaches from it. Am I allowed to take ibuprofen for the headaches? Are there any interactions btwn the two?

Ask your doctor: You should ask your doctor for the clearance to take other medications (even over the counters) while on Prozac (fluoxetine). Well, actually interesting you should ask because in fact, there are significant interactions which can cause either an increase in bleeding complications due to the ibuprofen or increased toxicity of the Prozac (fluoxetine). The combination should be closely monitored in general. Check with Doctor ...Read more

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I've been on Prozac (fluoxetine) for 2 months but have headaches. Now my doctor suggested amitriptyline. Is that an ok combo? I don't like having to take more meds

I've been on Prozac (fluoxetine) for 2 months but have headaches. Now my doctor suggested amitriptyline. Is that an ok combo? I don't like having to take more meds

Maybe: If the headache is new, then perhaps it is a side effect of the Prozac (fluoxetine). If that is the case you should talk to your doctor about changing the antidepressant before adding a new medication to address side effects. If you are prone to headaches, amitriptyline is a good option to decrease the amount of headaches. However, it is also an antidepressant and could cover both problems ...Read more

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Can Prozac (fluoxetine) effect periods. I started Prozac (fluoxetine) 6/25 and should have had a period for july. I've been having headaches and anxiety. Not sexually active.?

Can Prozac (fluoxetine) effect periods. I started Prozac (fluoxetine) 6/25 and should have had a period for july. I've been having headaches and anxiety. Not sexually active.?

Prozac (fluoxetine) and periods: Fluoxetine can affect menstruation patterns. Fluoxetine takes about 6 weeks to fully achieve positive effects. Anxiety and headaches are side effects. Talk to your doctor if you are unable to tolerate these side effects. Do not stop fluoxetine abruptly as these side effects can worsen. ...Read more

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I have ITP - never needed treatment. I'm on Prozac for anxiety. What can I take that is safe if I have a headache? Tylenol (acetaminophen)? Aleve?

I have ITP - never needed treatment. I'm on Prozac for anxiety. What can I take that is safe if I have a headache? Tylenol (acetaminophen)? Aleve?

Acetaminophen: Acetaminophen (Tylenol (acetaminophen) and many other over the counter meds) is safe because unlike Aleve (ibuprofen) it has no effect on platelet function. Aspirin and other non-steroidal anti-inflammatory drugs (NSAIDS) do affect platelet function, which increases risk of bleeding, which is already increased in ITP due a lower platelet count. ...Read more

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I just started taking Prozac and am still on Zoloft (sertraline) and I have been having neck pain and ear pain and headaches along with mucus in throaght. Normal?

I just started taking Prozac and am still on Zoloft (sertraline) and I have been having neck pain and ear pain and headaches along with mucus in throaght. Normal?

Well...: YOU SHOULD NOT BE TAKING PRAZAC AND ZOLOFT (sertraline) TOGETHER!
But your symptoms are very likely unrelated.
Contact your Dr. As soon as he or she is available ...Read more

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Is nausea headache shooting earache & shooting head pain teeth grinding dizzyness light headed all side effects of prozac (fluoxetine)?

Is nausea headache shooting earache & shooting head pain teeth grinding dizzyness light headed all side effects of prozac (fluoxetine)?

Not necessarily: Many of your symptoms appear to be related to a TMJ/TMD issue. Prozac (fluoxetine) does have some terrible side effects (bad effects,) and should be explored. But the question is if you had any of these symptoms prior to going on Prozac (fluoxetine). Get to your Dr. Or pharmacist and ask many questions. You may need more than one Dr. And/or a TMJ/TMD specialist. ...Read more

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Hi, I was given fluoxetine capsule tablets by the doctors for my headaches, they have since stopped, which is good, can you tell me why they stopped?

Serotonin, Sort of: Serotonin Reuptake Inhibitors like Fluoxetine are often effective in treating chronic headaches in part because Serotonin is depleted in most forms of chronic pain, such as headaches. A reuptake inhibitor allows the existing Serotonin to do more work. Serotonin is needed in the "ascending pain pathway" - the pain you feel from anywhere on/in your body. ...Read more

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Started taking fluoxetine 7 days ago and I've had some nasty headaches for 2 days now will they go away mainly at night before sleeping then occur?

SSRI's: SSRIs like Prozac are effective in some patients but not in general. There are other antidepressants with much greater effectiveness and fewer Headaches...ask your doctor for Brintillex or Remeron (mirtazapine) or an herbalist for an alternative. ...Read more

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I am having fluoxetine 20 mg about 5 month, still I get bed headache some time and felling dizziness at morning time, what to do for getting better? Y

Let MD know: If the headache/ dizziness occurred only after starting fluoxetine then it is likely to be the cause. Let your md know that you have side effects. Your doctor can switch you to a different medication. If the symptoms persist,
a further workup may be necessary. ...Read more

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Have headache from citalopram is this still side effects from it? But I have switched to fluoxetine now when can expect to go away?

Have headache from citalopram is this still side effects from it? But I have switched to fluoxetine now when can expect to go away?

Medicine half life: It is possible this is still a side effect of the old medicine, it is possible it is not a side effect. I would give this a week or so, it takes time for medicines to wear off. Hopefully the new medicine does not cause the same symptom. ...Read more

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What do I do if the fluoxetine causes headaches like the Citalopram? Just take Tylenol (acetaminophen) or ask Dr to see what they can do?

What do I do if the fluoxetine causes headaches like the Citalopram? Just take Tylenol (acetaminophen) or ask Dr to see what they can do?

Tylenol, (acetaminophen) other drug: You can take anything you'd like for the headache, perhaps with the exception of ultram (with caution), but talk to your doctor about a different class of drug for you depression ...Read more

Dr. Alan Ali
774 Doctors shared insights

Prozac (Definition)

Prozac is a serotonin reuptake blocker which is a kind of ...Read more