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Doctor insights on: Prozac And Buspar

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Dr. Alan Ali Dr. Ali
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How well do Prozac and Buspar (buspirone) interact?

Dr. Alan Ali Dr. Ali
1 doctor agreed:
How well do Prozac and Buspar (buspirone) interact?

Prozac/Buspar: No major negative interactions, except some nausea if taken together. ...Read more

Dr. Heidi Fowler
1,052 Doctors shared insights

Fluoxetine (Definition)

Fluoxetine (brand prozac) is an antidepressant in the class known as serotonin selective reuptake inhibitors aka ssris. Fda approved in 1987 for the treatment of major depressive disorder. Subsequently approved for obsessive compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder. Significantly safer and much better ...Read more


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Is it possible and safe to take the following combo (40 mg Prozac daily + Buspar (buspirone) 60 mg daily) permanently as an effective treatment for me for GAD?

Is it possible and safe to take the following combo (40 mg Prozac daily + Buspar (buspirone) 60 mg daily) permanently as an effective treatment for me for GAD?

Talk to your doctor: Before using this combo. Combining Buspar (buspirone) and Prozac can increase the risk of a rare but serious condition called serotonin syndrome. Buspar (buspirone) 60 mg is a max daily dose. ...Read more

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Doctor would like to add Buspar (buspirone) to Prozac, can Buspar (buspirone) lessen & encounter jerk and jittery of Prozac? And dose this combo cause significant weight gain?

Doctor would like to add Buspar (buspirone) to Prozac, can Buspar (buspirone) lessen & encounter jerk and jittery of Prozac? And dose this combo cause significant weight gain?

Be careful: Needs close watch by Dr! Risk of rare but bad Serotonin Syndrome - confusion, hallucination, seizure, big blood pressure chgs, fast heart rate, fever, sweating, shaking, blurred vision, muscle spasm/stiffness, tremor, incoordination, stomach cramp, nausea, and diarrhea. Severe cases may result in coma and even death. ...Read more

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If we need to control GAD&SAD with fewer possibility of weight gain and drowsiness so which combo more compatible: (BUSPAR/PROZAC) or (BUSPAR/ZOLOFT)?

If we need to control GAD&SAD with fewer possibility of weight gain and drowsiness so which combo more compatible: (BUSPAR/PROZAC) or (BUSPAR/ZOLOFT)?

It depends: Everyone is different so a trial and error attempt is often required. How about buproprion (Wellbutrin) and Buspar (buspirone)? SAD also can respond to light therapy so don't leave that option out. Also some patients with a diagnosis of GAD have other issues going on. Commonly they will have aspects of Post Traumatic Stress Disorder (PTSD) which can benefit from specific therapy. ...Read more

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Does the combo of (40 mg Prozac (fluoxetine) + 30 mg Buspar) daily, safe and effective for GAD? My doctor recommended that for treatment GAD and social phobia.

Does the combo of (40 mg Prozac (fluoxetine) + 30 mg Buspar) daily, safe and effective for GAD? My doctor recommended that for treatment GAD and social phobia.

Common Tx: Your complaints are often treated w/ such medications. Side effects of many sorts may occur and you need to report them to Dr immediately for adjustments. Effectiveness varies for people but all studies support adding CBT therapy to optimize outcome and minimize or replace the drugs. Work closely w/ Dr and a therapist to learn skills for a lifetime! ...Read more

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How soon can I start Buspar (buspirone) after prozac?

How soon can I start Buspar (buspirone) after prozac?

Immediately: In fact, Buspar (buspirone) and Prozac can be taken at the same time, so there's no need to wait if you stop one and start the other. ...Read more

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How long before I can start Buspar (buspirone) after stopping prozac?

See below: That depends on your prescribing physician's guidance but both can be taken together. ...Read more

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I am taking Buspar (buspirone) and Brintellix...is this combination safe. I just read where I should not be taking Prozac with Brintellix.

Same issues: It is NOT true that you cannot take two drugs that act on the serotonin system at the same time, only that you have to be CAREFUL, and that the dose of both drugs should be on the lower side, and they should be raised more slowly by lower increments. Also, you should be on lookout for symptoms of serotonin syndrome - anxiety, agitation, tremor. Talk to your doctor/pharmacist for better advice. ...Read more

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Thinking of asking for Buspar, (buspirone) so I don't have to be on Xanax, added to my Prozac and maybe an up on my dose (20 to 30). Thoughts?

Thinking of asking for Buspar, (buspirone) so I don't have to be on Xanax, added to my Prozac and maybe an up on my dose (20 to 30). Thoughts?

Anxiety: Buspirone is approved for the treatment of generalized anxiety disorder and is sometimes used off-label for other anxiety disorders and depression. For some patients it is very effective. Higher doses of an SSRI such as fluoxetine (Prozac) are often effective for anxiety. I would ask your physician about both of these changes, but DO NOT stop the Xanax (alprazolam) on your own, this can be very dangerous. ...Read more

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I have bi polar 1, im on Buspar (buspirone) Prozac and wellbutin. I am having a moderate panick attack and its getting worse. What's the best way to handle?

Get a second opinion: Your drug regimen does not include a mood stabilizer, which is essential in treatment of true bipolar disease. There is no good reason to be on two similar antidepressants, and wellbutrin (bupropion) has a known side effect of increasing anxiety. Prozac can be destabilizing in bipolar disease. The buspr doesn't seem to be doing a lot for your anxiety, but may work better if you change up the antidepressants. ...Read more

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What is the best anti anxiety depression med that has the least side effects. I did not care for buspar, (buspirone) celexa, or Prozac. Something not 2 addicting?

What is the best anti anxiety depression med that has the least side effects. I did not care for buspar, (buspirone) celexa, or Prozac. Something not 2 addicting?

Depends on you: Every patient is different and will respond better to certain medications while others may not respond well to a particular drug. Best to talk to your own doctor about medicine for anxiety/depression but other drugs such as wellbutrin or Effexor (venlafaxine) might also be useful for you. Of course exercise and good counseling are equally if not more important than any drug. Good luck! ...Read more

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Take treatment for GAD by Prozac 40 mg, my GP wants add either Buspar (buspirone) or Wellbutrin to encounter side effects of Prozac, which the safe and ideal combo?

Buspirone: You may want to talk to your doc about a psychiatry referral since it sounds like (a)he may be in over their head. Buspirone is an anti-anxiety drug, but both Prozac and Wellbutrin (bupropion) can potentially exacerbate anxiety. There are many other potential options if Buspirone is not beneficial, but I would not abandon it before max dose of 60 mg/d. It should be taken 3-4 times dailu ...Read more

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My doc gave me Buspar (buspirone) since 2 months now and it's not working. Also proved antidepressants like zoloft, efexor, cymbalta, prozac, wellbutrin, paxil?

Antidepressants: What is your question, it is confusing. Have you been all the antidepressants you mentioned or would like to try. You should consult your psychiatrist and discuss your concern. ...Read more

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Dr. Alan Ali Dr. Ali
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Is it safe to take fluoxetine and Buspar (buspirone), and clonazepam at the same time? . Thx.

Dr. Alan Ali Dr. Ali
1 doctor agreed:

Prozac/Buspar/Klonop: If prescribed by same physician, yes. Only concern, and that is dose-dependent, is more anxiety & stomach upset, but that should ease up with time. ...Read more

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I'm taking 10 mg buspar, (buspirone) 1 mg clonazepam daily, my dosage of fluoxetine was, just increased from 30 to 40mg...I have ringing in my ears constant...Thx.

Medication side effe: I can't tell from the description you provide what the time sequence is, but the first thing to do is always rule out a medication side effect. If it is safe for you to return to 30 mg of fluoxetine that might solve the problem. ...Read more

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Dr. Alan Ali
773 Doctors shared insights

Prozac (Definition)

Prozac is a serotonin reuptake blocker which is a kind of ...Read more


Dr. Michael Gabor
263 Doctors shared insights

Busipirone (Definition)

Busipirone is an addiction reducing agent which is a ...Read more