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Doctor insights on: Prothrombin Time Inr Calculation

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My prothrombin time INR is 1.5 is it dangerous?

My prothrombin time INR is 1.5 is it dangerous?

Why is it 1.5?: You probably mean inr of 1.5 (normal prothrombin time is about 12 seconds). It is not dangerous by itself but why is your inr prolonged? The disease process causing this prolongation may be dangerous, e.G, liver disease, malabsorption causing vitamin deficiency etc. Please consult your doctor to determine the cause and treat the underlying process. ...Read more

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Dr. Afshine Emrani
266 doctors shared insights

Inr (Definition)

Could mean interventional neuro radiology which is minimally invasive field, or international normalized ration which is a lab ...Read more


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B12 inj(500mcg) for a week, does it increase clotting time,bleeding time?does it affect prothrombin time & INR? what supplements needed on B12 therapy

B12 inj(500mcg) for a week, does it increase clotting time,bleeding time?does it affect prothrombin time & INR? what supplements needed on B12 therapy

B12: B12 itself will not influence clotting or bleeding. However, as anemia corrects, blood clotting improves. Platelet count can raise as B12 improves marrow. Take folic acid, other B vitamins, and get potassium from food. ...Read more

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My prothrombin time is 14.3 & inr is 1.32 . I am on acitrom 3 & acitrom 4 on alternate days... is it ok?

My prothrombin time is 14.3 & inr is 1.32 . I am on acitrom 3 & acitrom 4 on alternate days... is it ok?

Anticoagulation: Your INR appears subtherapeutic and you will need an adjustment in your anti vitamin K meds. Please call your prescriber and ask about recommendations regarding your doses. ...Read more

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Prothrombin time - 15.8 sec and INR - 1.2 what could be the reason for increase? and i am on B12 inj now for a week, does it affect them.hvy periods

Prothrombin time - 15.8 sec and INR - 1.2 what could be the reason for increase? and i am on B12 inj now for a week, does it affect them.hvy periods

See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, your prolonged PT is not likely to be the cause of heavy periods.There is no relation between B12 and prolonged PT either. Given the health issues you have, it is something best discussed with your doctor who has more information. ...Read more

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My prothrombin time is INR 1.3 with normal aptt and platelet counts. Do I have liver failure? Normal ast, alt, alp and bilirubin. Burns right stomach

My prothrombin time is INR 1.3 with normal aptt and platelet counts. Do I have liver failure? Normal ast, alt, alp and bilirubin. Burns right stomach

Probably not: The slight elevation in the inr with normal labs for the rest of your liver functions suggests you don't have liver disease. The burning could be coming from an ulcer, or gastritis, or esophagitis. The body doesn't do a good job of localizing pain coming from the internal organs, so where you feel the pain may not be where it is.. Follow up with your doctor to check out different causes. ...Read more

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What is the definition or description of: prothrombin time?

What is the definition or description of: prothrombin time?

PTT: Prothrombin time provides information regarding the extrinsic pathway involved in clot formation. It's commonly used to monitor warfarin therapy. ...Read more

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High prothrombin time levels affect bleeding?

High prothrombin time levels affect bleeding?

Yes.: Prothrombin times about three times higher than normal for the particular lab may be a risk for abnormal bleeding. ...Read more

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What is the prothrombin time in a blood test?

What is the prothrombin time in a blood test?

Measures clot factor: This is a test that measures clotting factor activity. All these factors are synthesized in the liver, except factor viii, so this is also a check on the capability of the liver as well. If this is high, it can be from a deficiency or incabability of the factors or a liver failure issue, like cirrhosis, or a vitamin k deficiency from fat malabsorption. This shoud be worked-up dr.'s office. ...Read more

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What does it mean if my prothrombin time blood test is high?

What does it mean if my prothrombin time blood test is high?

Blood clotting : Defective. Prolonged prothrombin time can be due to deficiency of a number of coagulation factors. A common cause it treatment with warfarin/coumdain. Liver disease is an other common reason for prolonged pt. Depending on the prolongation, the person may be at risk of bleeding. ...Read more

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Why is prothrombin time prolonged in eosinophilic gastroenteropathy?

Why is prothrombin time  prolonged in eosinophilic gastroenteropathy?

Likely vitamin K: Deficiency. An intestinal lesion is likely to be associated with malabsorption may result in deficiency of vitamin k among other nutrients and prolong prothrombin time. However, this is a long shot explanation and you should be investigated to exclude other causes. ...Read more

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Would a prothrombin time of 15.7 stop me from being able to donate my kidney?

Would a prothrombin time of 15.7 stop me from being able to donate my kidney?

Maybe: If your prothrombin time is prolonged, is it because of coumadine treatment or underlying liver disease? This question is best directed to your primary Medical Doctor. Good luck. ...Read more

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What does it mean when my prothrombin time blood test is high, compared to normal or low?

What does it mean when my prothrombin time blood test is high, compared to normal or low?

Can mean Vit K low.: If prothrombin time blood test is high, without other high levels, it can mean a vitamin k deficiency or warfarin use. Vitamin k helps in the function and viability of factors ii, vii, ix, and x and these affect prothrombin time. If there are other levels altered, it could be a factor v, or x deficiency, disseminated intravascular coagulation (dic), or liver failure. See your doctor to be sure. ...Read more

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What does a prothrombin time measurement do?

Extrinsic pathway of: Clotting. Pt is dependent on levels of multiple coagulation factors, including x, ix vii, v, and ii. ...Read more

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Decrease in prothrombin time can lead to what?

Decrease in prothrombin time can lead to what?

Repeat test.: A shortened clotting time that does not appear to reflect technical error has been associated with an increased risk of thrombosis, recurrent thrombosis, recurrent miscarriage, or bleeding, and may increase the risk of thrombosis associated with other common thrombotic risk factors (eg, factor v leiden, obesity, increased levels of d-dimer). ...Read more

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What is thrombocytopenia and how is a prothrombin time test used?

What is thrombocytopenia and how is a prothrombin time test used?

Blood clotting: Thrombocytopenia means low level of blood plateletes. Prothrombin time is a test for extrinsic coagulation pathway that is initiated with factor vii. Vitamin k deficiency or use of Coumadin (warfarin) or liver function deficiency will prolong the prothrombin time, while several blood clotting diseases that affect intrinsic coagulation such as von willibrand or hemophila will not affect prothrombin time. ...Read more

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My prothrombin time is 15.7. Will that be a problem if I have major surgery?

My prothrombin time is 15.7. Will that be a problem if I have major surgery?

Prothrombin time: An elevation in the Prothrombin time should be evaluated before you have surgery. There are many possible causes for this and it could pose a risk for you during surgery. ...Read more

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What types of drugs an foods interfere with the coagulation test of prothrombin time?

What types of drugs an foods interfere with the coagulation test of prothrombin time?

Depends on : Circumstances. In a normal person, usual drugs and foods do not affect pt measurably. In patients on warfarin, foods both prolong pt, e.g., grapefruit, or shorten it, e.g., green leafy vegetables. Many drugs affect pt, e.g., birth control pills, isoniazid, anti-fungals, antibiotics, and many other drugs metabolized through cytochrome p450 system, and barbiturates and alcohol. ...Read more

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I had an aptt of 36.5, a aptt 1:1 np of 33.3, and a prothrombin time of 13.5. All are listed under high but my doctor is not concerned? Is this ok?

Normal range?: More information is needed including the "normal range" of the tests. Why were the tests ordered? However the elevated aptt corrects with mixing with normal blood (1:1 mix) suggesting a coagulation factor deficiency. Consider repeat testing and asking for more information about cause. Your doctor may seek the opinion of a hematologist. ...Read more

Dr. Shimae Fitzgibbons
210 doctors shared insights

Prothrombin Time (Definition)

Prothrombin time provides information regarding the extrinsic pathway involved in clot formation. It's commonly used ...Read more