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Doctor insights on: Prothrombin Fragment 1 2

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2 kids with nonimmune hydrops, 1 f 2 1/2 yrs, 1 m 3 months?

2 kids with nonimmune hydrops, 1 f 2 1/2 yrs, 1 m 3 months?

Hydrops fetalis, : Excessive fluid build-up in 2 or more body parts in a fetus, can be pretty severe, as you describe. Non-immune hydrops can be from heart or lung problems, severe anemia (alpha-thalassemia or infections), genetic syndromes or problems in fetal development. I'd seek evaluations of both kids by a geneticist to look for a cause ; by your state's early intervention program to assess their development. ...Read more

Dr. Shimae Fitzgibbons
210 doctors shared insights

Prothrombin Time (Definition)

Prothrombin time provides information regarding the extrinsic pathway involved in clot formation. It's commonly used ...Read more


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Is SIRT worth doing for liver liver metastases 1x 7 cm 1x 6 cm 8 under 2 cm?

Is SIRT worth doing for liver liver metastases 

1x 7 cm
1x 6 cm
8 under 2 cm?

Yes: Multiple liver lesions can be treated by a number of approaches because what is in liver will not spread. Originally ligation of hepatic artery was used since portal vein supplies hepatocytes and hepatic artery the metastatic tumors.Can be used with SIRT which is a form of RT treatment wherein a dose of SIR-Spheres® microspheres are delivered up to 40 times higher than conventional doses. ...Read more

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7mm round firm node on chin above jawline. 2 sub centermeter nodes at lower neck. biopsy 3 mths ago on level 2 node indicates follicular hyperplasia.

7mm round firm node on chin above jawline. 2 sub centermeter nodes at lower neck. biopsy 3 mths ago on level 2 node indicates follicular hyperplasia.

Question?: Not sure what the question is here. Sounds like the diagnosis has been made already. Pretty large lymph nodes for follicular hyperplasia. Was treatment recommended or prescribed? ...Read more

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41yo F, feeling crappy 6 weeks, onset of unexplained hives, labs 8/25/16 WBC 12.5 , RBC 5.36 Hgb 15.7 Hct 49.6 MCH 29.3 MCH 31.7 RDW 13.3 RDWSD 45.0?

41yo F, feeling crappy 6 weeks, onset of unexplained hives, labs 8/25/16
WBC 12.5 , RBC 5.36 Hgb 15.7 Hct 49.6 
MCH 29.3 MCH 31.7 RDW 13.3 RDWSD 45.0?

Need medical examina: You need to see a doctor for medical check up to find the cause of Hives. It may be an allergic reaction to a medication or any chemicals in your environment. Your WBC count is also high, but we need to know the differential count, a breakdown of WBC into its component cells. You may need to see an allergist if the hives do not go away in a few days. Specialized tests(complement levels) may help ...Read more

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Wbc 13.2 RBC 4.73 hemoglobin 10.2 hematocrit 33.8 mvc 72 MCH 21.6 mchc 30.2 RDW 16.2 platelets 816, 000.Thoughts?Should i be worried with the platelets

Wbc 13.2 RBC 4.73 hemoglobin 10.2 hematocrit 33.8 mvc 72 MCH 21.6 mchc 30.2 RDW 16.2 platelets 816, 000.Thoughts?Should i be worried with the platelets

Probably reactive: You are anemic and the numbers are suspicious for iron deficiency. If you are a healthy 34 year-old who menstruates regularly, you could easily be low in iron. The plaelet count is very high, but is likely reacting to the low iron and should come down if it is replaced. The elevated white cells (WBC) is not as easy to understand. Inflamation, infection, other? Could use more info. Good luck. ...Read more

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30 yr albanian male. Joint pain, 99.8 temp, food allergies. Hemoglobin 6.7, RDW 18, mvc 74, platelets 530. Sed w rate 58. Ferr. 105, iron sat. 6.

30 yr albanian male. Joint pain, 99.8 temp, food allergies. Hemoglobin 6.7, RDW 18, mvc 74, platelets 530. Sed w rate 58. Ferr. 105, iron sat. 6.

U r seriously sick: You're a 30 year old man and no matter how dysfunctional your health care system is, you have a right to demand that your physician explain why you are apparently iron deficient. You have a bleeding ulcer or gastrointestinal cancer until proved otherwise. ...Read more

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What are the symptoms of an ear infection?

What are the symptoms of an ear infection?

Similar to teething: The symptoms of an ear infection - otitis media - can be remarkably similar to those of teething, with all of some of these symptoms: irritability; poor sleep; diarrhea; tugging at ear (placing finger in ear, or even hitting ear); low-grade fever. The only way to tell them apart is careful examination of the ears. ...Read more

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When would a baby of 1-2 months need prothrombin time testing? What are they looking for?

When would a baby of 1-2 months need prothrombin time testing? What are they looking for?

Unexplaind bruises: When a doctor orders prothrombin time and other clotting tests, he/she is probably looking for a bleeding disorder that may explain bruises in a baby that young. ...Read more

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Can i tell me if my normal prothrombin level is 2-3, what happens when it is 11 or higher?

Can i tell me if my normal prothrombin level is 2-3, what happens when it is 11 or higher?

PT or INR?: The normal prothrombin time is closer to 10 seconds. You may be confusing the INR, although an INR is normally 1.0 ; if you take certain types of blood thinners it could be 2-3. So, if you are asking what happens if your INR is >= 11: You could bleed to death. It is nothing to fool around with. ...Read more

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What happens if your normal prothrombin level is 2-3, what happens when it is 11 or higher?

What happens if your normal prothrombin level is 2-3, what happens when it is 11 or higher?

You may be confused: INR is a measure of blood clotting and is often kept at about 2 if you are on warfarin. An INR of 11 would be EXTREMELY dangerous and put you at very high risk of bleeding On the other hand, prothrombin levels measure a specific clotting factor and may have normal values (not on anticoagulants) near 11 depending on a particular lab. ...Read more

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What is prothrombin?

What is prothrombin?

Clotting factor: When activated, prothrombin becomes thrombin, which among other effects turns fibrinogen into the stick for fibrin to create a molecular meshwork that will become the basis for the scab. Protrombin time is a conventional name for one assay of the ability of the clotting factors (not platelets) to keep blood in the vessels. ...Read more

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What does a prothrombin time measurement do?

Extrinsic pathway of: Clotting. Pt is dependent on levels of multiple coagulation factors, including x, ix vii, v, and ii. ...Read more

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Decrease in prothrombin time can lead to what?

Decrease in prothrombin time can lead to what?

Repeat test.: A shortened clotting time that does not appear to reflect technical error has been associated with an increased risk of thrombosis, recurrent thrombosis, recurrent miscarriage, or bleeding, and may increase the risk of thrombosis associated with other common thrombotic risk factors (eg, factor v leiden, obesity, increased levels of d-dimer). ...Read more

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How can I get a normal range of prothrombin time?

How can I get  a normal range of prothrombin time?

12 Seconds, but INR: Normal prothrombin time varies a from lab to lab; the average value is about 12 seconds. To compensate for the variability, the ratio of each lab's normal to the patient value is reported as international normalized ratio (inr) and an inr of 1.0 is normal. ...Read more