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Doctor insights on: Proteinase 3 Antibody

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Discuss monoclonal antibody production?

Discuss monoclonal antibody production?

Monospecific Ab.: Monoclonal antibodies are those that are produced by the identical immune cells that are descended from the same parent cell. They produce anitibodies that bind to only one epitope or site on an antigen. This means that they are monospecific. This makes them useful in things like research because they can isolate a strain purely and completely. ...Read more

Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


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05/05/2016 Siemens Advia Centaur hep C antibody result positive.08/10/2016 Abbott Architect (cmia) hep C antibody result negative.Who is telling truth?

05/05/2016 Siemens Advia Centaur hep C antibody result positive.08/10/2016 Abbott Architect (cmia) hep C antibody result negative.Who is telling truth?

It's not really: a question of truth telling. No test is perfect: the proteins and reactants used in each test will respond to an individual's blood/biologic material, potentially, in a different way. Falsely positive or falsely negative results are not very unusual. You need to decide on a confirmatory strategy with your doctor. Retesting is necessary and an expert can help you weigh the evidence to decide result ...Read more

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Hi, antibody HIV test detects HIV 2 as well as HIV 1 at three months after a possible risk?

Hi, antibody HIV test detects HIV 2 as well as HIV 1 at three months after a possible risk?

HIV 2: If the test was designed to test for both type one and type two then you are 95% clear. If the test did not test for type two then you need that test. ...Read more

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Should i maintain the time gap while I am having antibiotic, if it is 3 times a day, is that mean 8 hrs exactly gap or 1 or 2 hrs before and after is ok?

Should i maintain the time gap while I am having antibiotic, if it is 3 times a day, is that mean 8 hrs exactly gap or 1 or 2 hrs before and after is ok?

Probably OK: The reason for the spacing is to maintain levels above the minimum bacteriostatic concentration for the particular organism being treated. Since Amoxicillin has a half-life of about one hour it should actually be taken every 4 hrs at minimum, but for a normally immune host it should be ok. If you are treating acute bronchitis this is probably worthless anyway since over 95% are due to a virus. ...Read more

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What is the blood test tissue transglutaminase antibody?

What is the blood test tissue transglutaminase antibody?

Coeliac Disease.: This is a test for the autoantibody to the transglutaminase protein. These are found in coeliac disease. This is a sign, that there is a reaction to transglutaminase protein and its binding with gliadin, a wheat protein, as well as cross reaction with the small intestine. Thus, patients cannot get nutrition from foods containing gliadin, and need a gluten-free diet.. ...Read more

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For 58+ F, Hb 10.8, RBC 3.66, PCV 34, MCV 94, MCHC 31, WBC 5.4, Pt 1.8, Iron 57, TIBC 255, TSI 22, RC 1.2, Ferritin 83 indicate which type of anemia ?

For 58+ F, Hb 10.8, RBC 3.66, PCV 34, MCV 94, MCHC 31, WBC 5.4, Pt 1.8, Iron 57, TIBC 255, TSI 22, RC 1.2, Ferritin 83 indicate which type of anemia ?

Mild anemia: Assuming you've had no recent bleeding episodes, these findings could be seen in mild/early anemia of chronic disease. Hgb and Hct are only boarder line low, and iron panel appears within the reference range. Even something as simple as a particularly heavy period could cause mild anemia of this type, though. If you have a chronic medical illness, it could cause this type of anemia. ...Read more

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My blood test results: total bilirubin: 1.41 h ast: 40 h alt: 100 h total alk phosphatase: 43 l serum total protein: 7.1 e.R. Said hepatitis?

My blood test results:
total bilirubin: 1.41 h
ast: 40 h
alt: 100 h
total alk phosphatase: 43 l
serum total protein: 7.1

e.R. Said hepatitis?

Let's try this...: I have only a little bit of the story you've shared. Perhaps it's time to see whether the ast and alt get back to normal after two weeks off alcohol and any not-totally-necessary meds you may be taking. If so, this is the start of a healthier life after alcohol. If not, the workup for virus infections, iron overload, wilson's, autoimmunity & need for exercise can begin. Good luck. ...Read more

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I'm hebs ag negative with a high anti hbs antibody from vaccination. This week's test was reported as hebs ag detected with anti hbs antibody of 513 miu/ml. Lft normal....Scared....Lab error?

I'm hebs ag negative with a high anti hbs antibody from vaccination.  This week's test was reported as hebs ag detected with anti hbs antibody of 513 miu/ml. Lft normal....Scared....Lab error?

Yes: That sounds like lab error. Your hbsab would provide immunity; i'm assuming yoru hbcab (core) is negative; i wouldn't worry, talk to your doctor about a retest if you are concerned, but even if you were infected, there is no reason for treatment at this time. ...Read more

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Does anyone have information on or personal experiences with antiphospholipid antibody syndrome?

Does anyone have information on or personal experiences with antiphospholipid antibody syndrome?

Miscarriage: Apa, along with lupus anti-coagulant antibody, are two antibodies that attack the areas in the cell wall of growing tissue, especially the fast-growing placental tissue of an early pregnancy. These are newly-discovered causes for recurrent miscarriage, but also place the patient at higher risk for developing a blood clot, especially with hormone use, later in life. ...Read more

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Does 3 Hiv negative test confirms your HIV negative?

Does 3 Hiv negative test confirms your HIV negative?

Need details: A single nucleic acid test after the interval during which this becomes positive is proof enough that you are not infected. You're young. I trust you'll play safe from now on, and if you continue to have obsessive thoughts that you have become infected, sit down with your physician or someone who's trained in helping you get back into control of these unwanted and unhelpful thoughts. ...Read more

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What is the purpose of monoclonal antibodies?

What is the purpose of monoclonal antibodies?

Diagnosis and Rx: Monoclonal antibodies are used in many diagnostic tests. These are also used in the treatment of some tumors. However, monoclonal immunoglobulins in a person are markers of disease, especially multiple myeloma. ...Read more

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How long before antibiotics heal cellulitis? My doctor said I should feel better in a few days. Well it’s been three days and i still feel horrible and my arm is still red and painful. Should i wait a little longer for the drugs to work or should I call m

How long before antibiotics heal cellulitis? My doctor said I should feel better in a few days. Well it’s been three days and i still feel horrible and my arm is still red and painful. Should i wait a little longer for the drugs to work or should I call m

Numerous factors: Recovery time fro m cellulitis varies widely due to many factors including how sensitive the bacteria are to the antibiotic. As long as it isn't getting worse three days is ok. Be sure too take the entire prescription even if symptoms go away in a couple of days if not improving by day 5-7 then call the office. Make note that asking how long is a good question to ask the prescribier 1st visit. ...Read more

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Been diagnosed with peripheral neuropathy blood test showed high immunoglobulin m w/polyclonal gammopathy. Kappa/lambda increase. Possible meaning?

Been diagnosed with peripheral neuropathy   blood test showed high immunoglobulin m w/polyclonal gammopathy. Kappa/lambda increase. Possible meaning?

PlasmaCellDIsorder: May have plasma cell disorder/multiple myeloma. Plasma cells are a type of white blood cells that produces immunoglobulin(antibodies). Multiple myeloma is a cancerous or excessive proliferation of these plasma cells which may lead to excessive high levels of calcium/bone pain/renal failure/anemia (low blood counts). Need to see hematologist (blood doctor specialist). ...Read more

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IDA? RBC 4.880 HGB 13.70 HCT 45.0 MCV 92.20 MCH 28.10 MCHC 30.40 RDW 14.50 PLT 368 Serum Iron, 178 Ferritin, 10.6 TIBC, 470 UIBC 292 Saturation 38%

IDA? 
RBC 4.880
HGB 13.70
HCT 45.0
MCV 92.20
MCH 28.10
MCHC 30.40
RDW 14.50
PLT 368
Serum Iron, 178
Ferritin, 10.6
TIBC, 470
UIBC  292
Saturation 38%

This looks good: I'm not sure what your question is here, but overall this information regarding your blood counts looks good. You don't look anemic, the platelets that clot your blood are in good levels, and your infection fighting WBC's are at a good level. Have a great evening! ...Read more

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Husband works in health field had testing came back as having antibodies to herpes 1 what does that mean or me he has no signs of anything ?

Husband works in health field had testing came back as having antibodies to herpes 1 what does that mean or me he has no signs of anything ?

Past exposure: The vast majority of adults have IgG antibodies to Herpes 1. The odds are strong that you do as well. This just means that years ago, probably in childhood, he (like almost everyone) was exposed to that virus. He may (or may not) have gotten a cold sore. Most people with healthy immune systems keep it in in check & never get cold sores, but some do when under stress. If no symptoms not contagious. ...Read more

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